7,266 research outputs found

    Superconformal mechanics, black holes, and non-linear realizations

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    The OSp(2|2)-invariant planar dynamics of a D=4 superparticle near the horizon of a large mass extreme black hole is described by an N=2 superconformal mechanics, with the SO(2) charge being the superparticle's angular momentum. The {\it non-manifest} superconformal invariance of the superpotential term is shown to lead to a shift in the SO(2) charge by the value of its coefficient, which we identify as the orbital angular momentum. The full SU(1,1|2)-invariant dynamics is found from an extension to N=4 superconformal mechanics.Comment: 19 pages, plain latex file. Slightly shortened version, two references adde

    Interação de locais e capacidades combinatórias de linhagens de milho em cruzamento dialélicos.

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    Neste trabalho foram utilizados 45 hibridos simples provenientes de cruzamentos dialelicos entre 10 linhagens de milho considerados de elite pelo Centro Nacional de Pesquisa de Milho e Sorgo. Esses hibridos foram estudados em ensaios em blocos casualizados, com quatro repeticoes, e instalados em dois municipios (locais) do estado de Minas Gerais (Sete Lagoas e Capinopolis), no ano agricola de 1976/77. Foi analisado apenas a producao de graos por parcela. Esses ensaios foram analisados individualmente e de forma conjunta. Com a finalidade de verificar a influencia dos locais sobre os parametros geneticos, testou-se a interacao das capacidades combinatorias com locais. Esse estudo indicou maior inconsistencia da capacidade geral de combinacao em ambientes diferentes, quando comparados com a capacidade especifica de combinacao

    Metallochaperones Are Needed for Mycobacterium tuberculosis and Escherichia coli Nicotinamidase-Pyrazinamidase Activity.

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    Mycobacterium tuberculosis nicotinamidase-pyrazinamidase (PZAse) is a metalloenzyme that catalyzes conversion of nicotinamide-pyrazinamide to nicotinic acid-pyrazinoic acid. This study investigated whether a metallochaperone is required for optimal PZAse activity. M. tuberculosis and Escherichia coli PZAses (PZAse-MT and PZAse-EC, respectively) were inactivated by metal depletion (giving PZAse-MT-Apo and PZAse-EC-Apo). Reactivation with the E. coli metallochaperone ZnuA or Rv2059 (the M. tuberculosis analog) was measured. This was repeated following proteolytic and thermal treatment of ZnuA and Rv2059. The CDC1551 M. tuberculosis reference strain had the Rv2059 coding gene knocked out, and PZA susceptibility and the pyrazinoic acid (POA) efflux rate were measured. ZnuA (200 μM) achieved 65% PZAse-EC-Apo reactivation. Rv2059 (1 μM) and ZnuA (1 μM) achieved 69% and 34.3% PZAse-MT-Apo reactivation, respectively. Proteolytic treatment of ZnuA and Rv2059 and application of three (but not one) thermal shocks to ZnuA significantly reduced the capacity to reactivate PZAse-MT-Apo. An M. tuberculosis Rv2059 knockout strain was Wayne positive and susceptible to PZA and did not have a significantly different POA efflux rate than the reference strain, although a trend toward a lower efflux rate was observed after knockout. The metallochaperone Rv2059 restored the activity of metal-depleted PZAse in vitro Although Rv2059 is important in vitro, it seems to have a smaller effect on PZA susceptibility in vivo. It may be important to mechanisms of action and resistance to pyrazinamide in M. tuberculosis Further studies are needed for confirmation.IMPORTANCE Tuberculosis is an infectious disease caused by the bacterium Mycobacterium tuberculosis and remains one of the major causes of disease and death worldwide. Pyrazinamide is a key drug used in the treatment of tuberculosis, yet its mechanism of action is not fully understood, and testing strains of M. tuberculosis for pyrazinamide resistance is not easy with the tools that are presently available. The significance of the present research is that a metallochaperone-like protein may be crucial to pyrazinamide's mechanisms of action and of resistance. This may support the development of improved tools to detect pyrazinamide resistance, which would have significant implications for the clinical management of patients with tuberculosis: drug regimens that are appropriately tailored to the resistance profile of a patient's individual strain lead to better clinical outcomes, reduced onward transmission of infection, and reduction of the development of resistant strains that are more challenging and expensive to treat

    Relato de Rhizoctonia solani AG-4 HG I em crisântemo (Papiro Branco e Amarelo) e R. solani AG-4 HG III em gipsófila no Estado de São Paulo, Brasil, e sua patogenicidade cruzada.

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    Resumo: Atualmente, grupamento de anastomose (AG) de Rhizoctonia sp. em crisântemo e ocorrência deste fungo em gipsófila ainda não foram realizados no Brasil. Assim, realizou-se teste de patogenicidade normal e cruzada e sequenciamento da região ITS-5.8S rDNA para identificar o AG de isolado obtido de plantas de crisântemo (Papiro branco) e de gipsófila, ambas originárias de Holambra/São Paulo,Brasil. Após os testes, relata-se pela primeira vez a ocorrência de R. solani AG-4 HGI em crisântemo (Papiro Branco e Amarelo) e R. solani AG-4 HG III em gipsófila, no estado de São Paulo,Brasil, e também a sua patogenicidade cruzada. Abstract: Currently, anastomosis groups (AG) of Rhizoctonia sp. on chrysanthemum and occurrence of this fungus on gypsophila have not been reported in Brazil. However, in the present study, normal and cross pathogenicity and sequencing of ITS-5.8S rDNA regions were used to confirm the AG of isolate of Rhizoctonia sp. obtained from chrysanthemum (White Papyrus) and from gypsophila plants cultivated in Holambra / São Paulo, Brazil. After these tests, it was confirmed the report of Rhizoctonia solani AG-4 HG I on chrysanthemum (White and Yellow Papyrus) and R. solani AG-4 HG III on gypsophila in the São Paulo state, Brazil, and also their cross pathogenicity

    Anomalous response of superconducting titanium nitride resonators to terahertz radiation

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    We present an experimental study of KIDs fabricated of atomic layer deposited TiN films, and characterized at radiation frequencies of 350350~GHz. The responsivity to radiation is measured and found to increase with increasing radiation powers, opposite to what is expected from theory and observed for hybrid niobium titanium nitride / aluminium (NbTiN/Al) and all-aluminium (all-Al) KIDs. The noise is found to be independent of the level of the radiation power. The noise equivalent power (NEP) improves with higher radiation powers, also opposite to what is observed and well understood for hybrid NbTiN/Al and all-Al KIDs. We suggest that an inhomogeneous state of these disordered superconductors should be used to explain these observations

    Critical sets of nonlinear Sturm-Liouville operators of Ambrosetti-Prodi type

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    The critical set C of the operator F:H^2_D([0,pi]) -> L^2([0,pi]) defined by F(u)=-u''+f(u) is studied. Here X:=H^2_D([0,pi]) stands for the set of functions that satisfy the Dirichlet boundary conditions and whose derivatives are in L^2([0,pi]). For generic nonlinearities f, C=\cup C_k decomposes into manifolds of codimension 1 in X. If f''0, the set C_j is shown to be non-empty if, and only if, -j^2 (the j-th eigenvalue of u -> u'') is in the range of f'. The critical components C_k are (topological) hyperplanes.Comment: 6 pages, no figure

    Divergência entre acessos de arroz irrigado brasileiro utilizando o método de Ward.

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    O objetivo do trabalho foi caracterizar a parecença entre 27 acessos de linhagens e cultivares brasileiras de sistema de cultivo irrigado da coleção nuclear de arroz da Embrapa, reunindo-os em grupos por meio da técnica de agrupamento de Ward aplicada a caracteres agronômicos

    Bibliografia de fertilidade de solos e nutrição da seringueira.

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    Esta bibliografia que representa uma coletânea geral de trabalhos com fertilidade de solos e nutrição de seringueira.bitstream/item/211082/1/Bibliografia-de-fertilidade-de-solos-completo.pd
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