Variability of the origin and course of the uterine artery in clinical practice

In 2020, approximately 287,000 mothers died during pregnancy or childbirth, with one of the leading causes of maternal mortality being peripartum hemorrhage. It can be treated both pharmacologically and procedurally, for example, through uterine artery ligation, embolization, or hysterectomy. In case of procedural treatment, it is essential for the medical team to familiarize themselves with the anatomical structure of the patient's uterine arteries. Various variations in the course of this vessel are distinguished, such as the uterine artery branching as a bifurcation with the inferior gluteal artery, a common trunk of the uterine artery with another vessel, or even its duplication. Using radiological techniques such as angiography, it is possible to visualize vessels and their variations, which can allow for better patient care. Unfamiliarity with the departure and trajectory of the uterine artery may be associated with an increased risk of postoperative complications, especially after hysterectomy, where the uterine arteries close at the level of the uterus or at the beginning of their departure from the internal iliac artery. Ligating them in other place may result in ischemia of an area that should be continuously supplied with blood. Also, during surgery, special attention should be paid to possible anatomical variations of the patient's uterine artery, which, although rare, can cause intraoperative complications. A thorough analysis of the departure and trajectory of the uterine artery by physicians can prevent postoperative complications and also allow for the safe conduct of embolization procedures. The following article presents a literature review on the departure and course of the uterine artery and its variations, as well as procedural interventions related to this vessel

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Art w/ Natalia

Art w/ Natalia is a non-profit program bridging the gap for a person in need of assisted living care and their succsses. The activities included will have an educational element in them to enable mental stimulation as well as a hand-on art activity to creatively stimulate the user\u27s mind and have follow-up studio art options, ranging from clay and mixed-media sculpture to sketching and painting. Art w/ Natalia gives the user a new sense of purpose, a feeling of happiness in their work, and a place to be given praise and feel valued by being part of an art show including the collection of artwork they have created. Even if art or art history was not their lifelong interest, it is becoming a part of who they are now and with the help of a couple extra hands to guide them, it is reestablishing their sense of pride within themselves that they may have lost otherwise

The Gavel

About the Gavel (Pitch Competition): The culmination of the Enterprise Studio course is the Gavel event that takes place at the end of the academic year. Out of all the superb project ideas that were entered in this inaugural competition, 6 of the most innovative and market-focused business ideas were selected to participate in the pitch competition. The Pitch Competition winner will receive the Gavel Prize, which consists of: The Award of a prize of seed capital of up to £30,000/$40,000 One year of start-up space for your project team in New York or London Dedicated mentor support for the first year of the business launch process Industry and investment introductions tailored to the winner\u27s business proposal. Meet the Judges Panel: MICHAEL CHUNG - CEO of BrandEd ADAM DINWIDDIE - Product Team Leader at Fairchain MELANIE GERLIS - Art market columnist for the Financial Times VISHAL KUMAR - CEO and co-Founder of the Alice Camera JEREMY RHODES - Director of Business Development and Originations for Yieldstreet / Athena Art Financehttps://digitalcommons.sia.edu/speaker/1030/thumbnail.jp