Toward a dynamical systems analysis of neuromodulation

This work presents some first steps toward a more thorough understanding of the control systems employed in evolutionary robotics. In order to choose an appropriate architecture or to construct an effective novel control system we need insights into what makes control systems successful, robust, evolvable, etc. Here we present analysis intended to shed light on this type of question as it applies to a novel class of artificial neural networks that include a neuromodulatory mechanism: GasNets. We begin by instantiating a particular GasNet subcircuit responsible for tuneable pattern generation and thought to underpin the attractive property of “temporal adaptivity”. Rather than work within the GasNet formalism, we develop an extension of the well-known FitzHugh-Nagumo equations. The continuous nature of our model allows us to conduct a thorough dynamical systems analysis and to draw parallels between this subcircuit and beating/bursting phenomena reported in the neuroscience literature. We then proceed to explore the effects of different types of parameter modulation on the system dynamics. We conclude that while there are key differences between the gain modulation used in the GasNet and alternative schemes (including threshold modulation of more traditional synaptic input), both approaches are able to produce tuneable pattern generation. While it appears, at least in this study, that the GasNet’s gain modulation may not be crucial to pattern generation , we go on to suggest some possible advantages it could confer

Host-Source Country linkages as determinants of foreign acquisitions by Indian MNEs

This experimental paper explains foreign acquisitions by Indian multinational enterprises by reference to location specific factors in both the source country (India) and host countries together with variables required designed to capture the distance between India and the host country, both geographic and psychic. The paper finds that country specific advantages play an important role in explaining Indian foreign acquisitions. The general model performs well and Indian institutional and domestic capital variables add explanatory value

Optical studies of two LMC X-ray transients : RX J0544.1-7100 and RX J0520.5-6932

We report observations which confirm the identities of the optical counterpart to the transient sources RX J0544.1-7100 and RX J0520.5-6932. The counterparts are suggested to be a B-type stars. Optical data from the observations carried out at ESO and SAAO, together with results from the OGLE data base, are presented. In addition, X-ray data from the RXTE all-sky monitor are investigated for long term periodicities. A strong suggestion for a binary period of 24.4d is seen in RX J0520.5-6932 from the OGLE data.Comment: 6 pages, 7 figure

Exploring emotions and cognitions in hoarding: a Q-methodology analysis

Background: The cognitions and emotions of people prone to hoarding are key components of the dominant cognitive behavioural model of hoarding disorder. Aims: This study sought to use Q-methodology to explore the thoughts and feelings of people that are prone to hoarding, to identify whether distinct clusters of participants could be found. Method: A 49-statement Q-set was generated following thematic analysis of initial interviews (n = 2) and a review of relevant measures and literature. Forty-one participants with problematic hoarding met various study inclusion criteria and completed the Q-sort (either online or offline). A by-person factor analysis was conducted and subsequent participant clusters compared on psychometric measures of mood, anxiety, hoarding and time taken on the online task as proxy for impulsivity. Results: Four distinct participant clusters were found constituting 34/41 (82.92%) of the participants, as the Q-sorts of n = 7 participants failed to cluster. The four clusters found were ‘overwhelmed’ (n = 11 participants); ‘aware of consequences’ (n = 13 participants); ‘object complexity’ (n = 6 participants) and ‘object–affect fusion’ (n = 4 participants). The clusters did not markedly differ with regard to hoarding severity, anxiety, depression or impulsivity. Conclusions: Whilst the participant clusters reflect extant research evidence, they also reveal significant heterogeneity and so prompt the need for further research investigating emotional and cognitive differences between people prone to hoarding

Particle methods for a virtual patient

The particle systems approach is a well known technique in computer graphics for modelling fuzzy objects such as fire and clouds. The algorithm has also been applied to different biomedical applications and this paper presents two such methods: a charged particle method for soft tissue deformation with integrated haptics; and a blood flow visualization technique based on boids. The goal is real time performance with high fidelity results

Computational requirements of the virtual patient

Medical visualization in a hospital can be used to aid training, diagnosis, and pre- and intra-operative planning. In such an application, a virtual representation of a patient is needed that is interactive, can be viewed in three dimensions (3D), and simulates physiological processes that change over time. This paper highlights some of the computational challenges of implementing a real time simulation of a virtual patient, when accuracy can be traded-off against speed. Illustrations are provided using projects from our research based on Grid-based visualization, through to use of the Graphics Processing Unit (GPU)

Relic Abundance of Asymmetric Dark Matter

We investigate the relic abundance of asymmetric Dark Matter particles that were in thermal equilibrium in the early universe. The standard analytic calculation of the symmetric Dark Matter is generalized to the asymmetric case. We calculate the asymmetry required to explain the observed Dark Matter relic abundance as a function of the annihilation cross section. We show that introducing an asymmetry always reduces the indirect detection signal from WIMP annihilation, although it has a larger annihilation cross section than symmetric Dark Matter. This opens new possibilities for the construction of realistic models of MeV Dark Matter.Comment: 20 pages, 11 figures, Accepted by JCA

Outbursts of EX Hydrae Revisited

We present optical spectroscopy of EX Hya during its 1991 outburst. This outburst is characterised by strong irradiation of the front face of the secondary star by the white dwarf, an overflowing stream which is seen strongly in HeII and by a dip in the light curves, which extends from 0.1-0.6 in the binary and spin phases. Strong irradiation of the accretion curtain and that of the inner regions of the disc led to strong emission of HeII and to the suppression of the Hg and Hb emission. Disc overflow was observed in quiescence in earlier studies, where the overflow stream material was modulated at high velocities close to 1000 km/s. In outburst, the overflowing material is modulated at even higher velocities (~1500 km/s). These are streaming velocities down the field lines close to the white dwarf. Evidence for material collecting near the outer edge of the disc and corotating with the accretion curtain was observed. In decline, this material and the accretion curtain obscured almost all the emission near binary phase 0.4, causing a dip. The dip minimum nearly corresponds with spin pulse minimum. This has provided additional evidence for an extended accretion curtain, and for the corotation of material with the accretion curtain at the outer edge of the disc. From these observations we suggest that a mechanism similar to that of Spruit & Taam, where outbursts result due to the storage and release of matter outside the magnetosphere, triggers the outbursts of EX Hya. This is followed by the irradiation of the secondary star due to accretion induced radiation.Comment: 12 pages, 14 figures, 1 table. Figures 6, 7, 8 and 11 at low resolution. Paper accepted by the Monthly Notices of the Royal Astronomical Societ