4,473 research outputs found

    Digging Deeper: James Connolly in America

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    This project continued research into James Connolly\u27s time in America from 1902-1910. It focused on primary sources in the hopes to unearth things not found in the secondary writing on Connolly’s activities during this influential time. The O’Brien papers are an eclectic collection of primary documents from Connolly’s life, including letters between James Connolly and his friend John Matheson, correspondence with other socialists, and some of Connolly’s own writing. The New York Call was a daily socialist newspaper that contains ads for Connolly’s lectures and his magazine, The Harp, as well as meetings of his organization, the Irish Socialist Federation. Through these primary sources and others, more of James Connolly’s activities and perspectives during his time in America come to light

    Noise Limited Computational Speed

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    In modern transistor based logic gates, the impact of noise on computation has become increasingly relevant since the voltage scaling strategy, aimed at decreasing the dissipated power, has increased the probability of error due to the reduced switching threshold voltages. In this paper we discuss the role of noise in a two state model that mimic the dynamics of standard logic gates and show that the presence of the noise sets a fundamental limit to the computing speed. An optimal idle time interval that minimizes the error probability, is derived

    On the structure of framed vertex operator algebras and their pointwise frame stabilizers

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    In this paper, we study the structure of a general framed vertex operator algebra. We show that the structure codes (C,D) of a framed VOA V satisfy certain duality conditions. As a consequence, we prove that every framed VOA is a simple current extension of the associated binary code VOA V_C. This result would give a prospect on the classification of framed vertex operator algebras. In addition, the pointwise frame stabilizer of V is studied. We completely determine all automorphisms in this pointwise stabilizer, which are of order 1, 2 or 4. The 4A-twisted sector and the 4A-twisted orbifold theory of the famous Moonshine VOA are also constructed explicitly. We verify that the top module of this twisted sector is of dimension 1 and of weight 3/4 and the VOA obtained by 4A-twisted orbifold construction of the moonshine VOA is isomorphic to the moonshine VOA itself.Comment: Version 3: 59 pages. Corrected version. 54 pages on my LaTeX system version 2: We add Theorem 5.16 in which we give a necessary and sufficient condtion for a code to be a structure code of a holomorphic framed VOA. "hyperref" style is also introduce

    Alien Registration- Buckingham, Hattie M. (Easton, Aroostook County)

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    https://digitalmaine.com/alien_docs/26598/thumbnail.jp

    Quantum Fluctuations of a Coulomb Potential as a Source of Flicker Noise

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    The power spectrum of quantum fluctuations of the electromagnetic field produced by an elementary particle is determined. It is found that in a wide range of practically important frequencies the power spectrum of fluctuations exhibits an inverse frequency dependence. The magnitude of fluctuations produced by a conducting sample is shown to have a Gaussian distribution around its mean value, and its dependence on the sample geometry is determined. In particular, it is demonstrated that for geometrically similar samples the power spectrum is inversely proportional to the sample volume. It is argued also that the magnitude of fluctuations induced by external electric field is proportional to the field strength squared. A comparison with experimental data on flicker noise measurements in continuous metal films is made.Comment: 11 pages, substantially corrected and extende

    Actions of Agonists, Fipronil and Ivermectin on the Predominant In Vivo Splice and Edit Variant (RDLbd, I/V) of the Drosophila GABA Receptor Expressed in Xenopus laevis Oocytes

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    Ionotropic GABA receptors are the targets for several classes of insecticides. One of the most widely-studied insect GABA receptors is RDL (resistance to dieldrin), originally isolated from Drosophila melanogaster. RDL undergoes alternative splicing and RNA editing, which influence the potency of GABA. Most work has focussed on minority isoforms. Here, we report the first characterisation of the predominant native splice variant and RNA edit, combining functional characterisation with molecular modelling of the agonist-binding region. The relative order of agonist potency is GABA> muscimol> TACA> β-alanine. The I/V edit does not alter the potency of GABA compared to RDLbd. Docking calculations suggest that these agonists bind and activate RDLbdI/V through a similar binding mode. TACA and β-alanine are predicted to bind with lower affinity than GABA, potentially explaining their lower potency, whereas the lower potency of muscimol and isoguvacine cannot be explained structurally from the docking calculations. The A301S (resistance to dieldrin) mutation reduced the potency of antagonists picrotoxin, fipronil and pyrafluprole but the I/V edit had no measurable effect. Ivermectin suppressed responses to GABA of RDLbdI/V, RDLbd and RDLbdI/VA301S. The dieldrin resistant variant also showed reduced sensitivity to Ivermectin. This study of a highly abundant insect GABA receptor isoform will help the design of new insecticides

    Flow field prediction and analysis, project fire final report

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    Flow field, and convective and radiative heating predictions for NASA Fire project reentry package trajectorie

    Influence of damping on the vanishing of the electro-optic effect in chiral isotropic media

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    Using first principles, it is demonstrated that radiative damping alone cannot lead to a nonvanishing electro-optic effect in a chiral isotropic medium. This conclusion is in contrast with that obtained by a calculation in which damping effects are included using the standard phenomenological model. We show that these predictions differ because the phenomenological damping equations are valid only in regions where the frequencies of the applied electromagnetic fields are nearly resonant with the atomic transitions. We also show that collisional damping can lead to a nonvanishing electrooptic effect, but with a strength sufficiently weak that it is unlikely to be observable under realistic laboratory conditions

    Hypotheses, evidence and relationships: The HypER approach for representing scientific knowledge claims

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    Biological knowledge is increasingly represented as a collection of (entity-relationship-entity) triplets. These are queried, mined, appended to papers, and published. However, this representation ignores the argumentation contained within a paper and the relationships between hypotheses, claims and evidence put forth in the article. In this paper, we propose an alternate view of the research article as a network of 'hypotheses and evidence'. Our knowledge representation focuses on scientific discourse as a rhetorical activity, which leads to a different direction in the development of tools and processes for modeling this discourse. We propose to extract knowledge from the article to allow the construction of a system where a specific scientific claim is connected, through trails of meaningful relationships, to experimental evidence. We discuss some current efforts and future plans in this area
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