A Comparative Analysis of the Three Versions of A Psalm Of Life

A Psalm of Life, the representative work of the famous American poet Henry Wadsworth Longfellow, is taken as the first English poem translated into Chinese. It was in the year 1865 that Thomas Francis Wade first translated it into Chinese and after that various versions with distinctive features have been turning up. This thesis endeavors to analyze three typical versions from three aspects, namely, the “form beauty”, the “sound beauty” and the “sense beauty”, according to the “three-beauty” principle of poem translation proposed by Professor Xu Yuanchong. The basic principles and methods of poem translation are concluded on the basis of the comparative analysis and the “Dynamic Equivalence” theory proposed by Eugene A. Nida. Key Words: poem translation, spiritual resemblance, formal resemblance, “three-beauty” principle, dynamic equivalence Résumé: Le Psaume de la vie, oeuvre réputée du poète américain Henry Wadsworth Longfellow, est considéré commé le premier poème anglais traduit en chinois. Depuis que Thomas Francis Wade l’a traduit la première fois en chinois en 1865, de nouvelles versions ne cessent d’apparaître dont chacune a son originalité. L’article présent, en vertu du principe de « trois beautés » dans la traduction du poème préconisé par le professeur Xu Yuanchong, entreprent une analyse comparative de ses trois versions les plus réprésentatives sur les plans de « beauté de forme », « beauté de son» et « beauté de signification ».A partir du résultlat d’analyse, se référant à la théorie de l’ « équivalence dynamique » du théoricien de traduction très connu Eugene A. Nida, l’auteur propose les principes fondamentaux de la traduction de la poésie. Mots-Clés: traduction de la poésie, similitude d’esprit, similitude de form

Interaction Between AP-1 Proteins and Glucocorticoid Receptors in Regulation of Lymphokine Activated Killer (LAK) Cell Activity in the Equine Species.

This project was performed in order to determine whether exercise-induced increases in plasma cortisol concentrations may be responsible for enhanced lymphokine activated killer (LAK) cell activity. Secondly, this project included preliminary experments which were designed to test the hypothesis that stimulatory effects of cortisol on LAK cell activity may be due to cross-talk between signalling systems important to glucocorticoid effects and stimuli which act through nuclear activator protein-1 (AP-1). Blood samples were collected from resting horses in order to determine whether the animals had normal plasma glucocorticoid concentrations. All horses included in these experiments had 10\sp{-7} to 10\sp{-8}M cortisol concentrations and samples collected over a 24 hour period exhibited a normal diurnal rhythm. Plasma cortisol concentrations were measured before and after injection of cortisol or vehicle and the beginning of exercise stress. Radioimmunoassayable cortisol concentrations were increased (P $\u3c$ 0.05) in cortisol treated animals. Vehicle injection did not affect cortisol concentrations. Exercise-stressed horses had higher (P $\u3c$ 0.05) basal cortisol concentrations compared to vehicle or cortisol-treated horses. Exercise significantly increased plasma cortisol at all time points. Cortisol injections did not elevate plasma cortisol to concentrations measured in exercise-stressed horses. Extracts from PBMCs were analyzed to determine if they contained immunoreactive (ir) AP-1 protein and glucocorticoid receptors (GR). Cell extracts were resolved by SDS-PAGE and blotted onto nitrocellulose membranes. Primary GR antibody bound to a single band ($\sim$100KD) which was similar to that reported for GRs from other species. Dot blots were used to detect ir-Fos and Jun in extracts from equine PBMCs. Extracts containing at least 90 ng of protein contained specifically labeled Fos and Jun. The last experiment cultured PBMCs with media, IL-2, IL-2 plus phorbol ester (TPA) or IL-2 plus cortisol. As compared to the media control, LAK cell activity was stimulated by IL-2 and inhibited by TPA and high dose cortisol. Immunoreactive-Jun was increased by TPA and this effect was abolished by 10\sp{-4}M cortisol. These experiments indicate that stimulatory effects of exercise on LAK cell activity are unlikely to be due to cortisol actions or to stimuli which act through protein kinase C/AP-1 messenger systems

Power System's Damping Analysis Based on RBF Neural Network1

AbstractIn this paper, to solve the problem that the uncertainty of selecting generator's damping coefficient in power system's transient simulation, RBF neural network is used to calculate damping coefficient in the transient process of generator, which uses power angle and angle acceleration as input variables and electromagnetic torque as output one. It is used the trained RBF network to carry on the analysis of damping torque, and dynamic damping coefficient can be obtained. Finally, it is analyzed by the classical model in SMIB. Simulation results show that this method can effectively calculate generator's damping coefficient

Differences in Expression of EGFR, Ki67 and p-EPK in Oral Cavity Squamous Cell Carcinoma

Purpose: To evaluate the expression of EGFR, Ki67, and p-EPK in oral cavity and oropharyngeal cancers, and to investigate their clinical significance as prognostic markers.Methods: One hundred patients who underwent curative surgery for oral cavity or oropharyngeal squamous cell carcinoma in a Chinese People’s Liberation Army General Hospital between March 1999 and October 2010 were evaluated. The level of protein expression of EGFR, Ki67 and p-EPK was assessed by immunohistochemistry. In situ hybridization was used to detect the existence of human papillomavirus (HPV).Results: Nineteen of 75 patients with oropharyngeal cancer showed HPV-positive tumors, and two of 72 patients with oral cavity cancer showed HPV-positive tumors. EGFR and Ki67 expression was significantly higher in oral cavity cancers than in oropharyngeal cancers (p = 0.005 and p = 0.001, respectively). Loss of p-EPK occurred significantly more frequently in oral cavity cancers than in oropharyngeal cancers (p = 0.004). Overexpression of EGFR and Ki67 and loss of p-EPK were observed more frequently in HPV negative tumors. Multivariate Cox regression analysis showed that Ki67 expression had a significantly unfavorable impact on relapse free survival in oropharyngeal cancer.Conclusion: The expression levels of EGFR, Ki67, and p-EPK differ between oropharyngeal and oral cavity cancer and it may be attributed to HPV-related molecular pathogenesis. The expression of Ki67 might be an unfavorable prognostic marker for relapse-free survival in oropharyngeal cancer.Keywords: EGFR; Ki67; p-EPK; Oral cavity squamous cell carcinoma, Expression differenc

Theoretical study on fatigue damage of sonic standing wave resonant drill-string

Acknowledgments This work was supported by the National Natural Science Foundation of China (Grant NO.51775523). The authors would like to thank Mr. Ali Hassanirad for his suggestions on FEA of drill pipe joint.Peer reviewedPostprin

Seismic demand for eccentric wall structures subjected to velocity pulse-like ground motions

The elastic and inelastic seismic demand of shear wall structures, with stiffness, strength and combined-stiffness-and-strength eccentricity, subjected to velocity pulse-like ground motions are investigated. Based on the axial load-bending moment interaction model and eight pulse-like ground motions, nonlinear dynamic time history analyses are conducted to single-story RC eccentric wall structures. The seismic demand is discussed in terms of the displacement, floor rotation and ductility, and the influence mechanism of different eccentricity types is revealed. The results show that the eccentric systems for pulse-like cases experience much higher elastic and inelastic seismic demand comparing to those for non-pulse-like cases. The axial compression ratio has certain effect on the inelastic seismic demand. The stiffness eccentricity is the key factor to the elastic seismic demand, while the strength eccentricity influences the inelastic seismic demand most. It is suggested that the strength eccentricity be added as a parameter in the inelastic analysis of eccentric structures, and the influence of axial load as well as velocity pulse-like effect of ground motions also be accounted in

(Amino­acetato-κ2 O,N)bis­(quinolin-8-olato-κ2 O,N)cobalt(III) methanol solvate

In the crystal structure of the title compound, [Co(C2H4NO2)(C9H6NO)2]·CH3OH, the CoIII atom is chelated by two quinolin-8-olate and one glycinate anions in a distorted octa­hedral coordination geometry. The five-membered chelating glycinate ring assumes an envelope conformation. The complex mol­ecules are assembled by inter­molecular N—H⋯O hydrogen bonding

Methylation status of individual CpG sites within Alu elements in the human genome and Alu hypomethylation in gastric carcinomas

<p>Abstract</p> <p>Background</p> <p><it>Alu </it>methylation is correlated with the overall level of DNA methylation and recombination activity of the genome. However, the maintenance and methylation status of each CpG site within <it>Alu </it>elements (<it>Alu</it>) and its methylation status have not well characterized. This information is useful for understanding natural status of <it>Alu </it>in the genome and helpful for developing an optimal assay to quantify <it>Alu </it>hypomethylation.</p> <p>Methods</p> <p>Bisulfite clone sequencing was carried out in 14 human gastric samples initially. A <it>Cac</it>8I COBRA-DHPLC assay was developed to detect methylated-<it>Alu </it>proportion in cell lines and 48 paired gastric carcinomas and 55 gastritis samples. DHPLC data were statistically interpreted using SPSS version 16.0.</p> <p>Results</p> <p>From the results of 427 <it>Alu </it>bisulfite clone sequences, we found that only 27.2% of CpG sites within <it>Alu </it>elements were preserved (4.6 of 17 analyzed CpGs, A ~ Q) and that 86.6% of remaining-CpGs were methylated. Deamination was the main reason for low preservation of methylation targets. A high correlation coefficient of methylation was observed between <it>Alu </it>clones and CpG site J (0.963), A (0.950), H (0.946), D (0.945). Comethylation of the sites H and J were used as an indicator of the proportion of methylated-<it>Alu </it>in a <it>Cac</it>8I COBRA-DHPLC assay. Validation studies showed that hypermethylation or hypomethylation of <it>Alu </it>elements in human cell lines could be detected sensitively by the assay after treatment with 5-aza-dC and M.<it>Sss</it>I, respectively. The proportion of methylated-<it>Alu </it>copies in gastric carcinomas (3.01%) was significantly lower than that in the corresponding normal samples (3.19%) and gastritis biopsies (3.23%).</p> <p>Conclusions</p> <p>Most <it>Alu </it>CpG sites are deaminated in the genome. 27% of <it>Alu </it>CpG sites represented in our amplification products. 87% of the remaining CpG sites are methylated. <it>Alu </it>hypomethylation in primary gastric carcinomas could be detected with the <it>Cac</it>8I COBRA-DHPLC assay quantitatively.</p

Development of 146nm Vacuum UV Light Source

AbstractThe principle of dielectric-barrier discharge (DBD) producing 146nm vacuum ultraviolet (VUV) light is introduced in this article. MgF2 and Kr are used as the output window and the discharge gas, respectively, in the VUV light source. Fairly wide, narrow-bandwidth UV light could be generated with peak wavelength of 146nm and a full width at half maxima of 12nm. In addition, the impact of air pressure, voltage amplitude and frequency to the light source is also analyzed

A novel frame-shift mutation in FRMD7 causes X-linked idiopathic congenital nystagmus in a Chinese family

Purpose: To screen mutations in the FERM domain-containing 7 (FRMD7) gene in a Chinese family with X-linked idiopathic congenital nystagmus (ICN). Methods: It has been reported that FRMD7 mutations account for approximately 47% of X-linked nystagmus in Chinese patients. We collected 5 ml of blood samples from members of a family with X-linked ICN and 100 normal controls. Mutations in FRMD7 were determined by sequencing PCR products. Results: We identified a previously unreported 4 bp deletion in FRMD7 (c.1486-1489 del TTTT) in a Chinese family. The mutation co-segregated with the disease phenotype in patients and female carriers, while it was not detected in other relatives or in the 100 normal controls. Conclusions: Our results expand the spectrum of FRMD7 mutations causing ICN, and further confirm the role of FRMD7 in the pathogenesis of ICN. Direct sequencing of FRMD7 could be used as a diagnostic testing of idiopathic congenital nystagmus.Biochemistry &amp; Molecular BiologyOphthalmologySCI(E)PubMed4ARTICLE297-992765-27681