135 research outputs found
Synthesis, characterization and thermal studies on solid state 3-methoxybenzoate of lighter trivalent lanthanides
Development and characterization of microsatellite loci in the Centricnemus leucogrammus weevil
Ethiopian indigenous goats offer insights into past and recent demographic dynamics and localadaptation in sub-Saharan African goats
Abstract Knowledge on how adaptive evolution and human socioâcultural and economic interests shaped livestock genomes particularly in subâSaharan Africa remains limited. Ethiopia is in a geographic region that has been critical in the history of African agriculture with ancient and diverse human ethnicity and bioâclimatic conditions. Using 52K genomeâwide data analysed in 646 individuals from 13 Ethiopian indigenous goat populations, we observed high levels of genetic variation. Although runs of homozygosity (ROH) were ubiquitous genomeâwide, there were clear differences in patterns of ROH length and abundance and in effective population sizes illustrating differences in genome homozygosity, evolutionary history, and management. Phylogenetic analysis incorporating patterns of genetic differentiation and gene flow with ancestry modelling highlighted past and recent intermixing and possible two deep ancient genetic ancestries that could have been brought by humans with the first introduction of goats in Africa. We observed four strong selection signatures that were specific to ArsiâBale and Nubian goats. These signatures overlapped genomic regions with genes associated with morphological, adaptation, reproduction and production traits due possibly to selection under environmental constraints and/or human preferences. The regions also overlapped uncharacterized genes, calling for a comprehensive annotation of the goat genome. Our results provide insights into mechanisms leading to genome variation and differentiation in subâSaharan Africa indigenous goats
Ancestral population genomics
Borrowing both from population genetics and phylogenetics, the field of population genomics emerged as full genomes of several closely related species were available. Providing we can properly model sequence evolution within populations undergoing speciation events, this resource enables us to estimate key population genetics parameters such as ancestral population sizes and split times. Furthermore we can enhance our understanding of the recombination process and investigate various selective forces. With the advent of resequencing technologies, genome-wide patterns of diversity in extant populations have now come to complement this picture, offering an increasing power to study more recent genetic history
Population genomics of speciation and admixture
The application of population genomics to the understanding of speciation has led to the emerging field of speciation genomics. This has brought new insight into how divergence builds up within the genome during speciation and is also revealing the extent to which species can continue to exchange genetic material despite reproductive barriers. It is also providing powerful new approaches for linking genotype to phenotype in admixed populations. In this chapter, we give an overview of some of the methods that have been used and some of the novel insights gained. We also outline some of the pitfalls of the most commonly used methods and possible problems with interpretation of the results
Synthesis, spectroscopic and thermal studies of 2,3-naphthalenedicarboxylates of rare earth elements
The Synthesis of Zinc(II) and Cadmium(II) 2,4-Dichlorophenoxyacetates in WaterâMethanol Environment. Structure and Properties of Polymeric [Zn(2,4-D)2(MeOH)2] n and [Cd(2,4-D)2(H2O)2] n
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