3,144 research outputs found
Preparation of a Resorbable Osteoinductive Tricalcium Phosphate Ceramic
Over the past decade we have demonstrated numerous times that calcium phosphates can be rendered with osteoinductive properties by introducing specific surface microstructures1. Since most of these calcium phosphates contained hydroxyapatite, they are either slowly or not resorbable2. Resorbability is an often sought after characteristic of calcium phosphates so that they can be gradually replaced by newly formed bone. The objective of this study was to prepare a resorbable surface microstructured tricalcium phosphate (TCP) ceramic and evaluate its osteoinductive property and resorption rate after intramuscular implantation in dogs. This material was then compared to the established and slowly resorbable osteoinductive biphasic calcium phosphate ceramic (BCP)
Photonic quasicrystals for general purpose nonlinear optical frequency conversion
We present a general method for the design of 2-dimensional nonlinear
photonic quasicrystals that can be utilized for the simultaneous phase-matching
of arbitrary optical frequency-conversion processes. The proposed scheme--based
on the generalized dual-grid method that is used for constructing tiling models
of quasicrystals--gives complete design flexibility, removing any constraints
imposed by previous approaches. As an example we demonstrate the design of a
color fan--a nonlinear photonic quasicrystal whose input is a single wave at
frequency and whose output consists of the second, third, and fourth
harmonics of , each in a different spatial direction
Theory of high harmonic generation in relativistic laser interaction with overdense plasma
High harmonic generation due to the interaction of a short ultra relativistic
laser pulse with overdense plasma is studied analytically and numerically. On
the basis of the ultra relativistic similarity theory we show that the high
harmonic spectrum is universal, i.e. it does not depend on the interaction
details. The spectrum includes the power law part for
, followed by exponential decay. Here
is the largest relativistic -factor of the plasma
surface and is the second derivative of the surface velocity at this
moment. The high harmonic cutoff at is parametrically
larger than the predicted by the ``oscillating mirror''
model based on the Doppler effect. The cornerstone of our theory is the new
physical phenomenon: spikes in the relativistic -factor of the plasma
surface. These spikes define the high harmonic spectrum and lead to attosecond
pulses in the reflected radiation.Comment: 12 pages, 9 figure
In Vitro Bone Formation Associated with Apatite Coated Polylactide
Bone formation onto poly(L-lactide), which was plasma-spray coated with various quantities of hydroxyapatite (0%, 15%, 36% and 100% coverage), was investigated in an in vitro assay. Rat bone marrow cells were grown on the different coatings and the cellular response and elaborated extracellular matrix was examined at the light and electron microscopical level after 1, 2 , 4 and 8 weeks of culture. Proliferation of cells into multilayers was seen on the 0% , 36% and 100% , but not on the 15 % coatings. Coinciding with this was the sparse formation of extracellular matrix on the latter, and its abundant appearance on the former three coatings. Scanning and transmission electron microscopy revealed a mineralized extracellular matrix on the 100% and 36% coatings after 2 and 4 weeks , respectively, and on the 15 % coating after 8 weeks. Mineralization was not observed on uncoated poly(L-lactide). At the interface between hydroxyapatite and the mineralized extracellular matrix, one or more electron dense layers were frequently observed , which showed morphological similarities with structures between these two entities in vivo. The results of this in vitro study show that, in the model used, hydroxyapatite is required to obtain the elaboration of mineralized extracellular matrix on poly(L-lactide)
Univalent Foundations and the UniMath Library
We give a concise presentation of the Univalent Foundations of mathematics outlining the main ideas, followed by a discussion of the UniMath library of formalized mathematics implementing the ideas of the Univalent Foundations (section 1), and the challenges one faces in attempting to design a large-scale library of formalized mathematics (section 2). This leads us to a general discussion about the links between architecture and mathematics where a meeting of minds is revealed between architects and mathematicians (section 3). On the way our odyssey from the foundations to the "horizon" of mathematics will lead us to meet the mathematicians David Hilbert and Nicolas Bourbaki as well as the architect Christopher Alexander
Probability distributions for quantum stress tensors in four dimensions
We treat the probability distributions for quadratic quantum fields, averaged
with a Lorentzian test function, in four-dimensional Minkowski vacuum. These
distributions share some properties with previous results in two-dimensional
spacetime. Specifically, there is a lower bound at a finite negative value, but
no upper bound. Thus arbitrarily large positive energy density fluctuations are
possible. We are not able to give closed form expressions for the probability
distribution, but rather use calculations of a finite number of moments to
estimate the lower bounds, the asymptotic forms for large positive argument,
and possible fits to the intermediate region. The first 65 moments are used for
these purposes. All of our results are subject to the caveat that these
distributions are not uniquely determined by the moments. However, we also give
bounds on the cumulative distribution function that are valid for any
distribution fitting these moments.We apply the asymptotic form of the
electromagnetic energy density distribution to estimate the nucleation rates of
black holes and of Boltzmann brains.Comment: 26 pages, 2 figure
Diffusive limits on the Penrose tiling
In this paper random walks on the Penrose lattice are investigated. Heat
kernel estimates and the invariance principle are shown
Web Service Discovery in a Semantically Extended UDDI Registry: the Case of FUSION
Service-oriented computing is being adopted at an unprecedented rate, making the effectiveness of automated service discovery an increasingly important challenge. UDDI has emerged as a de facto industry standard and fundamental building block within SOA infrastructures. Nevertheless, conventional UDDI registries lack means to provide unambiguous, semantically rich representations of Web service capabilities, and the logic inference power required for facilitating automated service discovery. To overcome this important limitation, a number of approaches have been proposed towards augmenting Web service discovery with semantics. This paper discusses the benefits of semantically extending Web service descriptions and UDDI registries, and presents an overview of the approach put forward in project FUSION, towards semantically-enhanced publication and discovery of services based on SAWSDL
On the Entropy and the Density Matrix of Cosmological Perturbations
We look at the transition to the semiclassical behaviour and the decoherence
process for the inhomogeneous perturbations in the inflationary universe. Two
different decoherence mechanisms appear: one dynamical, accompanied with a
negligible, if at all, entropy gain, and the other, effectively irreversible
dephasing, due to a rapid variation in time of the off-diagonal density matrix
elements in the post-inflationary epoch. We thus settle the discrepancies in
the entropy content of perturbations evaluated by different authors.Comment: LaTeX2e with the epsf packag
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