K−/K+K^-/K^+ ratios in relativistic heavy-ion collisions

We study $K^-/K^+$ ratios as a function of centrality (participant nucleon number), transverse mass ($m_t$), and rapidity, in heavy-ion collisions at beam energies between 1A and 2A GeV. We use the relativistic transport model that includes expicitly the strangeness degrees of freedom and consider two scenarios for kaon properties in dense matter, one with and one without medium modifications of their properties. In both scenarios, The $K^-/K^+$ ratio does not change very much with the centrality, while the $K/\pi$ and ${\bar K}/\pi$ ratios increase with increasing centrality. Significant differences are predicted, both in magnitudes and shapes, for the $m_t$ spectra and rapidity distributions of $K^-/K^+$ ratio. Experimental measurement of these ratios, currently under investigation by the FOPI, KaoS, E866, and E895 collaborations, will be useful in revealing the kaon in-medium properties.Comment: RevTex, 10 pages, including 17 postscript figures, submitted to Phys. Rev.

Difficulties in probing density dependent symmetry potential with the HBT interferometry

Based on the updated UrQMD transport model, the effect of the symmetry potential energy on the two-nucleon HBT correlation is investigated with the help of the coalescence program for constructing clusters, and the CRAB analyzing program of the two-particle HBT correlation. An obvious non-linear dependence of the neutron-proton (or neutron-neutron) HBT correlation function ($C_{np,nn}$) at small relative momenta on the stiffness factor $\gamma$ of the symmetry potential energy is found: when $\gamma \lesssim 0.8$, the $C_{np,nn}$ increases rapidly with increasing $\gamma$, while it starts to saturate if $\gamma \gtrsim 0.8$. It is also found that both the symmetry potential energy at low densities and the conditions of constructing clusters at the late stage of the whole process influence the two-nucleon HBT correlation with the same power.Comment: 11 pages, 4 figure

Enhancement of low-mass dileptons in SPS heavy-ion collisions: possible evidence for dropping rho meson mass in medium

Dilepton production in proton- and nucleus-induced reactions at SPS energies is studied in the relativistic transport model using initial conditions determined by the string dynamics from RQMD. It is found that both the CERES and HELIOS-3 data for dilepton spectra in proton-nucleus reactions can be well described by the conventional mechanism of Dalitz decay and direct vector meson decay. However, to provide a quantitative explanation of the observed dilepton spectra in central S+Au and S+W collisions requires contributions other than these direct decays. Introducing a decrease of vector meson masses in hot dense medium, we find that these heavy-ion data can also be satisfactorily explained. We also give predictions for Pb+Au collisions at 160 GeV/nucleon using current CERES mass resolution and acceptance.Comment: 8 pages, LaTeX, figures available from [email protected], contribution to QM'96, to appear in the proceeding

Mechanism of cellular uptake of genotoxic silica nanoparticles.

Mechanisms for cellular uptake of nanoparticles have important implications for nanoparticulate drug delivery and toxicity. We have explored the mechanism of uptake of amorphous silica nanoparticles of 14 nm diameter, which agglomerate in culture medium to hydrodynamic diameters around 500 nm. In HT29, HaCat and A549 cells, cytotoxicity was observed at nanoparticle concentrations ≥ 1 μg/ml, but DNA damage was evident at 0.1 μg/ml and above. Transmission electron microscopy (TEM) combined with energy-dispersive X-ray spectroscopy confirmed entry of the silica particles into A549 cells exposed to 10 μg/ml of nanoparticles. The particles were observed in the cytoplasm but not within membrane bound vesicles or in the nucleus. TEM of cells exposed to nanoparticles at 4°C for 30 minutes showed particles enter cells when activity is low, suggesting a passive mode of entry. Plasma lipid membrane models identified physical interactions between the membrane and the silica NPs. Quartz crystal microbalance experiments on tethered bilayer lipid membrane systems show that the nanoparticles strongly bind to lipid membranes, forming an adherent monolayer on the membrane. Leakage assays on large unilamellar vesicles (400 nm diameter) indicate that binding of the silica NPs transiently disrupts the vesicles which rapidly self-seal. We suggest that an adhesive interaction between silica nanoparticles and lipid membranes could cause passive cellular uptake of the particles

Medium Dependence of the Vector-Meson Mass: Dynamical and/or Brown-Rho Scaling?

We discuss the similarities and differences for the theories of Rapp, Wambach and collaborators (called R/W in short) and those based on Brown-Rho scaling (called B/R), as applied to reproduce the dileptons measured by the CERES collaboration in the CERN experiments. In both theories the large number of dileptons at invariant masses $\sim$~$m_\rho/2$ are shown to be chiefly produced by a density-dependent $\rho$-meson mass. In R/W the medium dependence is dynamically calculated using hadronic variables defined in the matter-free vacuum. In B/R scaling it follows from movement towards chiral symmetry restoration due to medium-induced vacuum change, and is described in terms of constituent (or quasiparticle) quarks. We argue that the R/W description should be reliable up to densities somewhat beyond nuclear density, where hadrons are the effective variables. At higher density there should be a crossover to constituent quarks as effective variables scaling according to B/R. In the crossover region, the two descriptions must be ``dual''.Comment: 13 pages LaTeX, incl. 5 eps-figures and appb.sty; Talk given at the Workshop on 'The Structure of Mesons, Baryons and Nuclei', Cracow, May 1998, in honor of J. Speth's 60th birthday, to be published in Acta Physica Polonica

A model comparison of resonance lifetime modifications, a soft equation of state and non-Gaussian effects on π−π\pi-\pi correlations at FAIR/AGS energies

HBT correlations of $\pi^--\pi^-$ pairs at FAIR/AGS energies are investigated by using the UrQMD transport model and the CRAB analyzing program. Three different possible sources (treatment of resonance lifetimes, a soft equation of state and non-Gaussian effects) to understand the HBT $R_O/R_S$ puzzle are investigated. Firstly, we find that different treatments of the resonance decay time can not resolve the HBT time-related puzzle, however it can modify the HBT radii at low transverse momenta to some extent to explain the data slightly. Secondly, with a soft equation of state with momentum dependence, the measured transverse momentum dependent HBT radii and $R_O/R_S$ ratio can be described fairly well. Thirdly, non-Gaussian effects are visible in the calculated correlation function. Using the Edgeworth expansion, one finds that the non-Gaussian effect is strongest in the longitudinal direction and weakest in the sideward direction.Comment: 18 pages, 6 figures. To be published in J.Phys.