6,070 research outputs found

    Homology stability for outer automorphism groups of free groups

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    We prove that the quotient map from Aut(F_n) to Out(F_n) induces an isomorphism on homology in dimension i for n at least 2i+4. This corrects an earlier proof by the first author and significantly improves the stability range. In the course of the proof, we also prove homology stability for a sequence of groups which are natural analogs of mapping class groups of surfaces with punctures. In particular, this leads to a slight improvement on the known stability range for Aut(F_n), showing that its i-th homology is independent of n for n at least 2i+2.Comment: Published by Algebraic and Geometric Topology at http://www.maths.warwick.ac.uk/agt/AGTVol4/agt-4-54.abs.htm

    The convergent validity of two sensory processing scales used with school - age children : comparing the sensory profile and the sensory processing measure

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    Abstract: Aim: To investigate the convergent validity between the Sensory Profile, the Sensory Profile School Companion, and the Home and Main Classroom Forms of the Sensory Processing Measure. Method: Thirty mothers completed the Sensory Profile and the Sensory Processing Measure - Home Form on one child each. Nineteen teachers of the same children completed the Sensory Profile School Companion and the Sensory Processing Measure - Main Classroom Form. Results: The Sensory Profile and the Sensory Processing Measure - Home Form were significantly correlated (rho=0.86, p less-than .01). The Sensory Profile School Companion and Sensory Processing Measure - Main Classroom Form were also significantly correlated (rho=.74, p less-than .01). Conclusion: The two sets of sensory processing scales had moderate levels of convergent validity.<br /

    Designing authentication with seniors in mind

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    Developers typically adopt perceived best practice, and in the case of authentication this means password security. However, given the wide range of technical solutions available and the diverse needs and limitations of older users, we suggest that the default adoption of electronic “username and password” authentication may not be 'best practice' or even good practice. This paper highlights some challenges faced by three seniors, each of whom has multiple age- related disabilities and concomitant life challenges. The result is that they cannot authenticate themselves when they need to access their devices and accounts. We conclude by suggesting a number of research directions calculated to address some of these challenges and promote inclusive design and allow for diverse user authentication

    Stepmothering: A Changing Role

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    The University Archives has determined that this item is of continuing value to OSU's history.Presenter: Karen Brown, Ph.D., Director, Institute of Social Work, Southwest Texas State University - "Stepmothering: A Changing Role".The Ohio State University College of Social Wor

    A Brighter Future: The Impact of Charter School Attendance on Student Achievement in Little Rock

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    This thesis analyzes what affects charter school attendance has on standardized test scores of public and charters in Little Rock, Arkansas. Policy implications and avenues for further research are also discussed

    Activity of species-specific antibiotics against Crohnʼs disease–associated adherent-invasive Escherichia coli

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    Background: Crohn's disease (CD) is associated with bacterial dysbiosis that frequently includes colonization by adherent-invasive Escherichia coli (AIEC). AIEC are adept at forming biofilms and are able to invade host cells and stimulate the production of proinflammatory cytokines. The use of traditional antibiotics for the treatment of CD shows limited efficacy. In this study, we investigate the use of species-specific antibiotics termed colicins for treatment of CD-associated AIEC. Methods: Colicin activity was tested against a range of AIEC isolates growing in the planktonic and biofilm mode of growth. Colicins were also tested against AIEC bacteria associated with T84 intestinal epithelial cells and surviving inside RAW264.7 macrophages using adhesion assays and gentamicin protection assay, respectively. Uptake of colicins into eukaryotic cells was visualized using confocal microscopy. The effect of colicin treatment on the production of proinflammatory cytokine tumor necrosis factor alpha by macrophages was assessed by an enzyme-linked immunosorbent assay. Results: Colicins show potent activity against AIEC bacteria growing as biofilms when delivered either as a purified protein or through a colicin-producing bacterial strain. In addition, colicins E1 and E9 are able to kill cell-associated and intracellular AIEC, but do not show toxicity toward macrophage cells or stimulate the production of proinflammatory cytokines. Colicin killing of intracellular bacteria occurs after entry of colicin protein into AIEC-infected macrophage compartments by actin-mediated endocytosis. Conclusions: Our results demonstrate the potential of colicins as highly selective probiotic therapeutics for the eradication of E. coli from the gastrointestinal tract of patients with CD

    Freshwater (aquatic) plants

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    pp. 107-10

    Lance and Nina : a story of addiction and redemption

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    PodcastKaren Brown is the 2015 winner of the Miller Audio Prize Contest in the Audio Documentary category for her entry titled, "Lance and Nina: a story of addiction and redemption.
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