Parametric pumping at finite frequency

We report on a first principles theory for analyzing the parametric electron pump at a finite frequency. The pump is controlled by two pumping parameters with phase difference $\phi$. In the zero frequency limit, our theory predicts the well known result that the pumped current is proportional to $\sin\phi$. For the more general situation of a finite frequency, our theory predicts a non-vanishing pumped current even when the two driving forces are in phase, in agreement with the recent experimental results. We present the physical mechanism behind the nonzero pumped current at $\phi=0$, which we found to be due to photon-assisted processes

The moderating effect of cognitive abilities on the association between sensory processing and emotional and behavioural problems and social participation in autistic individuals

Education and Child Studie

Serum 25-hydroxyvitamin D and parathyroid hormone in relation to plasma B-type natriuretic peptide: the Hoorn Study

OBJECTIVE: A disturbed vitamin D-parathyroid hormone (PTH)-calcium axis may play a role in the pathogenesis of heart failure. Therefore, we investigated whether lower 25-hydroxyvitamin D (25(OH)D) and higher PTH are cross sectionally and after 8 years of follow-up associated with higher B-type natriuretic peptide (BNP) levels in older men and women. DESIGN AND METHODS: We measured baseline 25(OH)D, PTH, and BNP in 502 subjects in 2000-2001 in the Hoorn Study, a population-based cohort. Follow-up BNP was available in 2007-2009 in 278 subjects. Subjects were categorized according to season- and sex-specific quartiles of 25(OH)D and PTH at baseline. We studied the association of 25(OH)D and PTH quartiles with BNP using linear regression analyses adjusting for confounders. Analyses were stratified by kidney function estimated glomerular filtration rate (eGFR; ≤60 ml/min per 1.73 m(2)) because of significant interaction. RESULTS: At baseline, subjects had a mean age of 69.9±6.6 years, mean 25(OH)D level was 52.2±19.5 nmol/l and mean PTH 6.1±2.4 pmol/l. Cross sectionally, 25(OH)D was associated with BNP in subjects with impaired kidney function (eGFR ≤60 ml/min) only. The association attenuated after adjustment for PTH. PTH was cross sectionally associated with BNP, also in subjects with impaired kidney function only: regression coefficient of highest quartile 9.9 pmol/l (95% confidence interval 2.5, 17.4) with a significant trend across quartiles. Neither 25(OH)D nor PTH was associated with BNP in longitudinal analyses. CONCLUSION: This study showed overall no strong association between 25(OH)D and BNP. However, PTH was associated with BNP in subjects with impaired kidney function and may point to a potential role in myocardial function

Fokker-Planck equations and density of states in disordered quantum wires

We propose a general scheme to construct scaling equations for the density of states in disordered quantum wires for all ten pure Cartan symmetry classes. The anomalous behavior of the density of states near the Fermi level for the three chiral and four Bogoliubov-de Gennes universality classes is analysed in detail by means of a mapping to a scaling equation for the reflection from a quantum wire in the presence of an imaginary potential.Comment: 10 pages, 5 figures, revised versio

Vitamin D in relation to myocardial structure and function after eight years of follow-up: the Hoorn study.

Background and Aims: To investigate associations between baseline serum 25-hydroxyvitamin D [25(OH)D] levels and myocardial structure and function after 8 years of follow-up in older Dutch subjects. Methods: We included 256 subjects of the Hoorn Study, a population-based cohort. They underwent a standardized 2-dimensional echocardiogram at baseline between 2000 and 2001, and again between 2007 and 2009. We studied the association of 25(OH)D quartiles with echocardiographic measures of the left ventricular mass index (LVMI), left ventricular systolic function and markers of diastolic function using linear regression analyses. Results: At baseline, subjects had a mean age of 67.4 ± 5.2 years and 41.4% had prior cardiovascular disease (CVD). Low serum 25(OH)D levels were only associated with higher LVMI at 8-year follow-up in subjects without prior CVD and in subjects with low kidney function (median estimated glomerular filtration rate ≤77.5 ml/min/1.73

Superconducting ``metals'' and ``insulators''

We propose a characterization of zero temperature phases in disordered superconductors on the basis of the nature of quasiparticle transport. In three dimensional systems, there are two distinct phases in close analogy to the distinction between normal metals and insulators: the superconducting "metal" with delocalized quasiparticle excitations and the superconducting "insulator" with localized quasiparticles. We describe experimental realizations of either phase, and study their general properties theoretically. We suggest experiments where it should be possible to tune from one superconducting phase to the other, thereby probing a novel "metal-insulator" transition inside a superconductor. We point out various implications of our results for the phase transitions where the superconductor is destroyed at zero temperature to form either a normal metal or a normal insulator.Comment: 18 page

Low-dose folic acid supplementation does not influence plasma methionine concentrations in young non-pregnant women

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