83 research outputs found
GWAS-based association between RWDD3 and TECTA variants and paclitaxel induced neuropathy could not be confirmed in Scandinavian ovarian cancer patients
Topiramate-associated acute glaucoma in a migraine patient receiving concomitant citalopram therapy: a case-report
We describe the case of a 34 year-old man with diagnosis of migraine with and without aura that developed myopia and acute glaucoma after 7 days of treatment with topiramate. The patient had also been taking citalopram daily for two months. Both topiramate and citalopram have been related to the increase of intraocular pressure and the development of glaucoma. We can't exclude that in this patient citalopram caused an increase of the ocular pressure in dose-dependent manner, facilitating topiramate-induced glaucoma. We recommend to pay particular attention in prescribing of topiramate in migraine patients who are already under treatment with citalopram or other antidepressants with a similar mechanisms of action
The B-VITAGE trial: A randomized trial of homocysteine lowering treatment of depression in later life
Influences on the pharmacokinetics of oxycodone: a multicentre cross-sectional study in 439 adult cancer patients
Pharmacogenomics and migraine: possible implications
Pharmacogenomics is the science about how inherited factors influence the effects of drugs. Drug response is always a result of mutually interacting genes with important modifications from environmental and constitutional factors. Based on the genetic variability of pharmacokinetic and in some cases pharmacodynamic variability we mention possible implications for the acute and preventive treatment of migraine. Pharmacogenomics will most likely in the future be one part of our therapeutic armamentarium and will provide a stronger scientific basis for optimizing drug therapy on the basis of each patient’s genetic constitution
Clinical pharmacology 2001 - important events. The Danish Society of Clinical Pharmacology
Duplication of CYP2D6 predicts high clearance of desipramine but high clearance does not predict duplication of CYP2D6
The oxidative metabolism of metoprolol in human liver microsomes: inhibition by the selective serotonin reuptake inhibitors.
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