1,903 research outputs found
A variational approach to moment-closure approximations for the kinetics of biomolecular reaction networks
Approximate solutions of the chemical master equation and the chemical
Fokker-Planck equation are an important tool in the analysis of biomolecular
reaction networks. Previous studies have highlighted a number of problems with
the moment-closure approach used to obtain such approximations, calling it an
ad-hoc method. In this article, we give a new variational derivation of
moment-closure equations which provides us with an intuitive understanding of
their properties and failure modes and allows us to correct some of these
problems. We use mixtures of product-Poisson distributions to obtain a flexible
parametric family which solves the commonly observed problem of divergences at
low system sizes. We also extend the recently introduced entropic matching
approach to arbitrary ansatz distributions and Markov processes, demonstrating
that it is a special case of variational moment closure. This provides us with
a particularly principled approximation method. Finally, we extend the above
approaches to cover the approximation of multi-time joint distributions,
resulting in a viable alternative to process-level approximations which are
often intractable.Comment: Minor changes and clarifications; corrected some typo
Interference effects in the counting statistics of electron transfers through a double quantum dot
We investigate the effect of quantum interferences and Coulomb interaction on
the counting statistics of electrons crossing a double quantum dot in a
parallel geometry using a generating function technique based on a quantum
master equation approach. The skewness and the average residence time of
electrons in the dots are shown to be the quantities most sensitive to
interferences and Coulomb coupling. The joint probabilities of consecutive
electron transfer processes show characteristic temporal oscillations due to
interference. The steady-state fluctuation theorem which predicts a universal
connection between the number of forward and backward transfer events is shown
to hold even in the presence of Coulomb coupling and interference.Comment: 11 pages, 12 figure
Learning SO(3) Equivariant Representations with Spherical CNNs
We address the problem of 3D rotation equivariance in convolutional neural
networks. 3D rotations have been a challenging nuisance in 3D classification
tasks requiring higher capacity and extended data augmentation in order to
tackle it. We model 3D data with multi-valued spherical functions and we
propose a novel spherical convolutional network that implements exact
convolutions on the sphere by realizing them in the spherical harmonic domain.
Resulting filters have local symmetry and are localized by enforcing smooth
spectra. We apply a novel pooling on the spectral domain and our operations are
independent of the underlying spherical resolution throughout the network. We
show that networks with much lower capacity and without requiring data
augmentation can exhibit performance comparable to the state of the art in
standard retrieval and classification benchmarks.Comment: Camera-ready. Accepted to ECCV'18 as oral presentatio
Evolution of cosmological constant in effective gravity
In contrast to the phenomenon of nullification of the cosmological constant
in the equilibrium vacuum, which is the general property of any quantum vacuum,
there are many options in modifying the Einstein equation to allow the
cosmological constant to evolve in a non-equilibrium vacuum. An attempt is made
to extend the Einstein equation in the direction suggested by the
condensed-matter analogy of the quantum vacuum. Different scenarios are found
depending on the behavior of and the relation between the relaxation parameters
involved, some of these scenarios having been discussed in the literature. One
of them reproduces the scenario in which the effective cosmological constant
emerges as a constant of integration. The second one describes the situation,
when after the cosmological phase transition the cosmological constant drops
from zero to the negative value; this scenario describes the relaxation from
this big negative value back to zero and then to a small positive value. In the
third example the relaxation time is not a constant but depends on matter; this
scenario demonstrates that the vacuum energy (or its fraction) can play the
role of the cold dark matter.Comment: LaTeX file, 5 pages, no figures, version submitted to JETP Letter
The 30/20 GHz flight experiment system, phase 2. Volume 2: Experiment system description
A detailed technical description of the 30/20 GHz flight experiment system is presented. The overall communication system is described with performance analyses, communication operations, and experiment plans. Hardware descriptions of the payload are given with the tradeoff studies that led to the final design. The spacecraft bus which carries the payload is discussed and its interface with the launch vehicle system is described. Finally, the hardwares and the operations of the terrestrial segment are presented
The 30/20 GHz flight experiment system, phase 2. Volume 1: Executive summary
Summary information on the final communication system design, communication payload, space vehicle, and development plan for the 30/20 GHz flight experiment will be installed on the LEASAT spacecraft which will be placed into orbit from the space shuttle cargo bay. The communication concept has two parts: a truck service and a customer premise service (CPS). The trucking system serves four spot beams which are interconnected in a satellite switched time division multiple access mode by an IF switch matrix. The CPS covers two large areas of the eastern United States with a pair of scanning beams
The 30/20 GHz flight experiment system, phase 2. Volume 3: Experiment system requirement document
An approach to the requirements document to be used to procure the system by NASA is presented. The basic approach is similar to the requirements document used in the commercial communication satellite. Enough detail requirements are given to define the system without tight constraints
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