Multi-Spacecraft Magnetic Field Reconstructions: A Cross-Scale Comparison of Methods

Space plasma studies frequently use in situ magnetic field measurements taken from many spacecraft simultaneously. A useful data product of these measurements is the reconstructed magnetic field in a volume near the spacecraft observatory. We compare a standard method of computing the magnetic field at arbitrary spatial points, the Curlometer, to two novel approaches: a Radial Basis Function interpolation and a time-dependent 2D inverse distance weighted interpolation scheme called Timesync. These three methods, which only require in situ measurements of the magnetic fields and bulk plasma velocities at a sparse set of spatial points, are implemented on synthetic data drawn from a time-evolving numerical simulation of plasma turbulence. We compare both the topology of the reconstructed field to the ground truth of the simulation and the statistics of the fluctuations found in the reconstructed field to those from the simulated turbulence. We conclude that the Radial Basis Function and Timesync methods outperform the Curlometer in both the topological and statistical comparisons.Comment: 29 pages, 10 figures, 2 tables, 1 appendix, repositories containing cod

A kinematic analysis of a haptic handheld stylus in a virtual environment: a study in healthy subjects

<p>Abstract</p> <p>Background</p> <p>Virtual Reality provides new options for conducting motor assessment and training within computer-generated 3 dimensional environments. To date very little has been reported about normal performance in virtual environments. The objective of this study was to evaluate the test-retest reliability of a clinical procedure measuring trajectories with a haptic handheld stylus in a virtual environment and to establish normative data in healthy subjects using this haptic device.</p> <p>Methods</p> <p>Fifty-eight normal subjects; aged from 20 to 69, performed 3 dimensional hand movements in a virtual environment using a haptic device on three occasions within one week. Test-retest stability and standardized normative data were obtained for all subjects.</p> <p>Results</p> <p>No difference was found between test and retest. The limits of agreement revealed that changes in an individual's performance could not be detected. There was a training effect between the first test occasion and the third test occasion. Normative data are presented.</p> <p>Conclusion</p> <p>A new test was developed for recording the kinematics of the handheld haptic stylus in a virtual environment. The normative data will be used for purposes of comparison in future assessments, such as before and after training of persons with neurological deficits.</p

Flow Quality Surveys in the Settling Chamber of the NASA Glenn Icing Research Tunnel (2011 Tests)

In 2011, the heat exchanger and refrigeration plant for NASA Glenn Research Centers Icing Research Tunnel (IRT) were upgraded. Flow quality surveys were performed in the settling chamber of the IRT in order to understand the effect that the new heat exchanger had on the flow quality upstream of the spray bars. Measurements were made of the total pressure, static pressure, total temperature, airspeed, and flow angle (pitch and yaw). These measurements were directly compared to measurements taken in 2000, after the previous heat exchanger was installed. In general, the flow quality appears to have improved with the new heat exchanger

Depressive symptoms and clustering of risk behaviours among adolescents and young adults attending vocational education: a cross-sectional study

BACKGROUND: Depressive symptoms and risk behaviours often do not occur in isolation among adolescents and young adults. In order to improve intervention programmes, more research is needed to elucidate the clustering of risk behaviours, the association with depressive symptoms, and demographic variables. Therefore, this study examined the clustering of risk behaviours, the association with depressive symptoms, and demographic variables among adolescents and young adults in vocational education. Furthermore, the prevalence of depressive symptoms and risk behaviours was examined.METHODS: This study included 584 students (mean age 18.3 years) attending vocational education in the Netherlands. Depressive symptoms and risk behaviours (binge drinking, cannabis use, smoking, delinquency and incurring debts) were assessed with self-report questionnaires. Truancy was monitored via the school registration system. Principal Components Analysis (PCA) was conducted to assess the factor structure of the risk behaviours (i.e. clustering). Linear regression analyses with a bootstrapping method were performed to assess the associations.RESULTS: Binge drinking was reported by 50.5% and cannabis use by 14.2% of the students (both in the past 4 weeks), whereas 37.7% reported currently being a smoker. More than 10% reported having been questioned at a police station in the past year. Furthermore, 82.2% had been truanting in the first two months of education, 21.0% reported having debts and 29.2% reported clinically-relevant depressive symptoms. The PCA indicated two clusters. The 'substance use' cluster consisted of the risk behaviours: binge drinking, cannabis use and smoking. The 'problem behaviours' cluster consisted of the risk behaviours: delinquency, truancy and incurring debts. Both clusters were associated with depressive symptoms. Various demographic variables were associated with both clusters.CONCLUSIONS: Risk behaviours formed two clusters, both of which were associated with depressive symptoms. These findings underscore the importance of screening adolescents and young adults at lower educational levels for multiple risk behaviours and depressive symptoms and of focusing on multiple risk behaviours in interventions simultaneously

Longitudinal Trajectories of Gestational Thyroid Function: A New Approach to Better Understand Changes in Thyroid Function

Context Most studies of thyroid function changes during pregnancy use a cross-sectional design comparing means between groups rather than similarities within groups. Objective Latent class growth analysis (LCGA) is a novel approach to investigate longitudinal changes that provide dynamic understanding of the relationship between thyroid status and advancing pregnancy. Design Prospective observational study with repeated assessments. Setting General community. Patients Eleven hundred healthy women were included at 12 weeks’ gestation. Main Outcome Measures The existence of both free T4 (fT4) and TSH trajectories throughout pregnancy determined by LCGA. Results LCGA revealed three trajectory classes. Class 1 (n = 1019; 92.4%), a low increasing TSH reference group, had a gradual increase in TSH throughout gestation (from 1.1 to 1.3 IU/L). Class 2 (n = 30; 2.8%), a high increasing TSH group, displayed the largest increase in TSH (from 1.9 to 3.3 IU/L). Class 3 (n = 51; 4.6%), a decreasing TSH group, had the largest fall in TSH (from 3.2 to 2.4 IU/L). Subclinical hypothyroidism at 12 weeks occurred in up to 60% of class 3 women and was accompanied by elevated thyroid peroxidase antibodies (TPO-Ab) titers (50%) and a parental history of thyroid dysfunction (23%). In class 2, 70% of women were nulliparous compared with 46% in class 1 and 49% in class 3. Conclusions LCGA revealed distinct trajectories of longitudinal changes in fT4 and TSH levels during pregnancy in 7.4% of women. These trajectories were correlated with parity and TPO-Ab status and followed patterns that might reflect differences in pregnancy-specific immune tolerance between nulliparous and multiparous women

2D vs. 3D pain visualization: User preferences in a spinal cord injury cohort

This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2011 Springer VerlagResearch on pain experienced after Spinal Cord Injury (SCI) has revealed that not only are there several types of pain present in the same individual with this kind of trauma, but also that people who suffer such an injury can describe the characteristics of the same type of pain in different ways. Making it possible, therefore, to more precisely describe pain experience could prove to be vital for an increased quality of life. Accordingly, fifteen individuals with pain after SCI were asked to describe their pain experience using a 3 Dimensional (3D) model of the human body that could be used as an aid in communicating their pain. The results of this study suggest that the consensus of the participants approved the ability of the 3D model to more accurately describe their pain, an encouraging outcome towards the use of 3D technology in support of post SCI pain rehabilitation

Magnetic Field Reconstruction for a Realistic Multi-Point, Multi-Scale Spacecraft Observatory

Future in situ space plasma investigations will likely involve spatially distributed observatories comprised of multiple spacecraft, beyond the four and five spacecraft configurations currently in operation. Inferring the magnetic field structure across the observatory, and not simply at the observation points, is a necessary step towards characterizing fundamental plasma processes using these unique multi-point, multi-scale data sets. We propose improvements upon the classic first-order reconstruction method, as well as a second-order method, utilizing magnetometer measurements from a realistic nine-spacecraft observatory. The improved first-order method, which averages over select ensembles of four spacecraft, reconstructs the magnetic field associated with simple current sheets and numerical simulations of turbulence accurately over larger volumes compared to second-order methods or first-order methods using a single regular tetrahedron. Using this averaging method on data sets with fewer than nine measurement points, the volume of accurate reconstruction compared to a known magnetic vector field improves approximately linearly with the number of measurement points.Comment: 18 pages, 12 figures, 3 table

Flow Quality Surveys in the Settling Chamber of the NASA Glenn Icing Research Tunnel (2011 Tests)

In 2011, the heat exchanger and refrigeration plant for NASA Glenn Research Center's Icing Research Tunnel (IRT) were upgraded. Flow quality surveys were performed in the settling chamber of the IRT in order to understand the effect that the new heat exchanger had on the flow quality upstream of the spray bars. Measurements were made of the total pressure, static pressure, total temperature, airspeed, and ow angle (pitch and yaw). These measurements were directly compared to measurements taken in 2000, after the previous heat exchanger was installed. In general, the flow quality appears to have improved with the new heat exchanger

The effectiveness of acellular nerve allografts compared to autografts in animal models:A systematic review and meta-analysis

Background Treatment of nerve injuries proves to be a worldwide clinical challenge. Acellular nerve allografts are suggested to be a promising alternative for bridging a nerve gap to the current gold standard, an autologous nerve graft. Objective To systematically review the efficacy of the acellular nerve allograft, its difference from the gold standard (the nerve autograft) and to discuss its possible indications. Material and methods PubMed, Embase and Web of Science were systematically searched until the 4th of January 2022. Original peer reviewed paper that presented 1) distinctive data; 2) a clear comparison between not immunologically processed acellular allografts and autologous nerve transfers; 3) was performed in laboratory animals of all species and sex. Meta analyses and subgroup analyses (for graft length and species) were conducted for muscle weight, sciatic function index, ankle angle, nerve conduction velocity, axon count diameter, tetanic contraction and amplitude using a Random effects model. Subgroup analyses were conducted on graft length and species. Results Fifty articles were included in this review and all were included in the meta-analyses. An acellular allograft resulted in a significantly lower muscle weight, sciatic function index, ankle angle, nerve conduction velocity, axon count and smaller diameter, tetanic contraction compared to an autologous nerve graft. No difference was found in amplitude between acellular allografts and autologous nerve transfers. Post hoc subgroup analyses of graft length showed a significant reduced muscle weight in long grafts versus small and medium length grafts. All included studies showed a large variance in methodological design. Conclusion Our review shows that the included studies, investigating the use of acellular allografts, showed a large variance in methodological design and are as a consequence difficult to compare. Nevertheless, our results indicate that treating a nerve gap with an allograft results in an inferior nerve recovery compared to an autograft in seven out of eight outcomes assessed in experimental animals. In addition, based on our preliminary post hoc subgroup analyses we suggest that when an allograft is being used an allograft in short and medium (0-1cm, &gt; 1-2cm) nerve gaps is preferred over an allograft in long (&gt; 2cm) nerve gaps.</p