Cross-language high similarity search using a conceptual thesaurus

This work addresses the issue of cross-language high similarity and near-duplicates search, where, for the given document, a highly similar one is to be identified from a large cross-language collection of documents. We propose a concept-based similarity model for the problem which is very light in computation and memory. We evaluate the model on three corpora of different nature and two language pairs English-German and English-Spanish using the Eurovoc conceptual thesaurus. Our model is compared with two state-of-the-art models and we find, though the proposed model is very generic, it produces competitive results and is significantly stable and consistent across the corpora.This work was done in the framework of the VLC/CAMPUS Microcluster on Multimodal Interaction in Intelligent Systems and it has been partially funded by the European Commission as part of the WIQ-EI IRSES project (grant no. 269180) within the FP 7 Marie Curie People Framework, and by the Text-Enterprise 2.0 research project (TIN2009-13391-C04-03). The research work of the second author is supported by the CONACyT 192021/302009 grantGupta, P.; Barrón Cedeño, LA.; Rosso, P. (2012). Cross-language high similarity search using a conceptual thesaurus. En Information Access Evaluation. Multilinguality, Multimodality, and Visual Analytics. Springer Verlag (Germany). 7488:67-75. https://doi.org/10.1007/978-3-642-33247-0_8S6775748

Steroid-sparing agents in giant cell arteritis

Background: Giant cell arteritis is the commonest form of medium-to-large vessel vasculitis, requiring long-term corticosteroid therapy. The short- and long-term side effects of corticosteroids are many, including weight gain, psychological effects, osteoporosis, cardiometabolic complications, and infections. Materials and Methods: Various agents used in place of or in combination with corticosteroids to reduce corticosteroid-related side effects were reviewed. However, considerable variation in practice was identified giving unclear guidance. This review included the most recent evidence on methotrexate, mycophenolate mofetil, azathioprine, cyclophosphamide, abatacept, and tocilizumab Results and Discussion: Also discussed are encouraging results with tocilizumab in GCA patients. Amongst the agents available for steroid-sparing effects, tocilizumab demonstrated the most robust data and is consequently recommended as the agent of choice for steroid-sparing, for remission induction, remission maintenance, and treating relapsing and refractory cases of GCA.Published versio