11,606 research outputs found
Time Dependent Clustering Analysis of the Second BATSE Gamma-Ray Burst Catalog
A time dependent two-point correlation-function analysis of the BATSE 2B
catalog finds no evidence of burst repetition. As part of this analysis, we
discuss the effects of sky exposure on the observability of burst repetition
and present the equation describing the signature of burst repetition in the
data. For a model of all burst repetition from a source occurring in less than
five days we derive upper limits on the number of bursts in the catalog from
repeaters and model-dependent upper limits on the fraction of burst sources
that produce multiple outbursts.Comment: To appear in the Astrophysical Journal Letters, uuencoded compressed
PostScript, 11 pages with 4 embedded figure
Simple versus optimal rules as guides to policy
This paper contributes to the policy evaluation literature by developing new strategies to study alternative policy rules. We compare optimal rules to simple rules within canonical monetary policy models. In our context, an optimal rule represents the solution to an intertemporal optimization problem in which a loss function for the policymaker and an explicit model of the macroeconomy are specified. We define a simple rule to be a summary of the intuition policymakers and economists have about how a central bank should react to aggregate disturbances. The policy rules are evaluated under minimax and minimax regret criteria. These criteria force the policymaker to guard against a worst-case scenario, but in different ways. Minimax makes the worst possible model the benchmark for the policymaker, while minimax regret confronts the policymaker with uncertainty about the true model. Our results indicate that the case for a model-specific optimal rule can break down when uncertainty exists about which of several models is true. Further, we show that the assumption that the policymaker’s loss function is known can obscure policy trade-offs that exist in the short, medium, and long run. Thus, policy evaluation is more difficult once it is recognized that model and preference uncertainty can interact.
Warped Supersymmetric Unification with Non-Unified Superparticle Spectrum
We present a new supersymmetric extension of the standard model. The model is
constructed in warped space, with a unified bulk symmetry broken by boundary
conditions on both the Planck and TeV branes. In the supersymmetric limit, the
massless spectrum contains exotic colored particles along with the particle
content of the minimal supersymmetric standard model (MSSM). Nevertheless, the
model still reproduces the MSSM prediction for gauge coupling unification and
does not suffer from a proton decay problem. The exotic states acquire masses
from supersymmetry breaking, making the model completely viable, but there is
still the possibility that these states will be detected at the LHC. The
lightest of these states is most likely A_5^XY, the fifth component of the
gauge field associated with the broken unified symmetry. Because supersymmetry
is broken on the SU(5)-violating TeV brane, the gaugino masses generated at the
TeV scale are completely independent of one another. We explore some of the
unusual features that the superparticle spectrum might have as a consequence.Comment: 21 pages, Latex, version to appear in Phys. Rev.
UHB demonstrator interior noise control flight tests and analysis
The measurement and analysis of MD-UHB (McDonnell Douglas Ultra High Bypass) Demonstrator noise and vibration flight test data are described as they relate to passenger cabin noise. The analyses were done to investigate the interior noise characteristics of advanced turboprop aircraft with aft-mounted engines, and to study the effectiveness of selected noise control treatments in reducing passenger cabin noise. The UHB Demonstrator is an MD-80 test aircraft with the left JT8D engine replaced with a prototype UHB engine. For these tests, the UHB engine was a General Electric Unducted Fan, with either 8x8 or 10x8 counter-rotating propeller configurations. Interior noise level characteristics were studied for several altitudes and speeds, with emphasis on high altitude (35,000 ft), high speed (0.75 Mach) cruise conditions. The effectiveness of several noise control treatments was evaluated based on cabin noise measurements. The important airborne and structureborne transmission paths were identified for both tonal and broadband sources using the results of a sound intensity survey, exterior and interior noise and vibration data, and partial coherence analysis techniques. Estimates of the turbulent boundary layer pressure wavenumber-frequency spectrum were made, based on measured fuselage noise levels
Elevated levels of interleukin-12/23p40 may serve as a potential indicator of dysfunctional heart rate variability in type 2 diabetes
BACKGROUND: Systemic inflammatory processes plausibly contribute to the development of cardiovascular complications, causing increased morbidity and mortality in type 2 diabetes. Circulating inflammatory markers, i.e., interleukin (IL)-6 and tumour necrosis factor-α, are associated with neurocardiac measures. We examined a broad panel of various inflammatory and inflammation-related serum markers to obtain more detailed insight into the possible neuro-immune interaction between cardiovascular regulation and systemic level of inflammation. METHODS: Serum samples from 100 participants with type 2 diabetes were analysed. Heart rate variability, cardiovascular autonomic reflex tests, and cardiac vagal tone tests were performed based on electrocardiographic readings. Data regarding covariates (demographic-, diabetes-, and cardiovascular risk factors) were registered. RESULTS: Increased serum levels of IL-12/IL-23p40 (p < 0.01) and intercellular adhesion molecule (ICAM)-1 (p < 0.007) were associated with diminished heart rate variability measures. After all adjustments, the associations between IL-12/23p40, SDANN and VLF persisted (p = 0.001). Additionally, serum levels of vascular endothelial growth factor (VEGF)-C were associated with response to standing (p = 0.005). DISCUSSION: The few but robust associations between neurocardiac regulation and serum markers found in this study suggest systemic changes in proinflammatory, endothelial, and lymphatic function, which collectively impacts the systemic cardiovascular function. Our results warrant further exploration of IL-12/IL-23p40, ICAM-1, and VEGF-C as possible cardiovascular biomarkers in T2D that may support future decisions regarding treatment strategies for improved patient care. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12933-021-01437-w
X-ray scattering from surfaces: discrete and continuous components of roughness
Incoherent surface scattering yields a statistical description of the
surface, due to the ensemble averaging over many independently sampled volumes.
Depending on the state of the surface and direction of the scattering vector
relative to the surface normal, the height distribution is discrete,
continuous, or a combination of the two. We present a treatment for the
influence of multimodal surface height distributions on Crystal Truncation Rod
scattering. The effects of a multimodal height distribution are especially
evident during in situ monitoring of layer-by-layer thin-film growth via Pulsed
Laser Deposition. We model the total height distribution as a convolution of
discrete and continuous components, resulting in a broadly applicable
parameterization of surface roughness which can be applied to other scattering
probes, such as electrons and neutrons. Convolution of such distributions could
potentially be applied to interface or chemical scattering. Here we find that
this analysis describes accurately our experimental studies of SrTiO3
annealing and homoepitaxial growth.Comment: 15 pages, 7 figure
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Social and endocrine correlates of immune function in meerkats: implications for the immunocompetence handicap hypothesis.
Social status can mediate effects on the immune system, with profound consequences for individual health; nevertheless, most investigators of status-related disparities in free-ranging animals have used faecal parasite burdens to proxy immune function in the males of male-dominant species. We instead use direct measures of innate immune function (complement and natural antibodies) to examine status-related immunocompetence in both sexes of a female-dominant species. The meerkat is a unique model for such a study because it is a cooperatively breeding species in which status-related differences are extreme, evident in reproductive skew, morphology, behaviour, communication and physiology, including that dominant females naturally express the greatest total androgen (androstenedione plus testosterone) concentrations. We found that, relative to subordinates, dominant animals had reduced serum bacteria-killing abilities; also, relative to subordinate females, dominant females had reduced haemolytic complement activities. Irrespective of an individual's sex or social status, androstenedione concentrations (but not body condition, age or reproductive activity) negatively predicted concurrent immunocompetence. Thus, dominant meerkats of both sexes are immunocompromised. Moreover, in female meerkats, androstenedione perhaps acting directly or via local conversion, may exert a double-edged effect of promoting dominance and reproductive success at the cost of increased parasitism and reduced immune function. Given the prominent signalling of dominance in female meerkats, these findings may relate to the immunocompetence handicap hypothesis (ICHH); however, our data would suggest that the endocrine mechanism underlying the ICHH need not be mediated solely by testosterone and might explain trade-offs in females, as well as in males
Necessary Optimality Conditions for Higher-Order Infinite Horizon Variational Problems on Time Scales
We obtain Euler-Lagrange and transversality optimality conditions for
higher-order infinite horizon variational problems on a time scale. The new
necessary optimality conditions improve the classical results both in the
continuous and discrete settings: our results seem new and interesting even in
the particular cases when the time scale is the set of real numbers or the set
of integers.Comment: This is a preprint of a paper whose final and definite form will
appear in Journal of Optimization Theory and Applications (JOTA). Paper
submitted 17-Nov-2011; revised 24-March-2012 and 10-April-2012; accepted for
publication 15-April-201
Estimating the functional form for the density dependence from life history data
Two contrasting approaches to the analysis of population dynamics are currently popular: demographic approaches where the associations between demographic rates and statistics summarizing the population dynamics are identified; and time series approaches where the associations between population dynamics, population density, and environmental covariates are investigated. In this paper, we develop an approach to combine these methods and apply it to detailed data from Soay sheep (Ovis aries). We examine how density dependence and climate contribute to fluctuations in population size via age- and sex-specific demographic rates, and how fluctuations in demographic structure influence population dynamics. Density dependence contributes most, followed by climatic variation, age structure fluctuations and interactions between density and climate. We then simplify the density-dependent, stochastic, age-structured demographic model and derive a new phenomenological time series which captures the dynamics better than previously selected functions. The simple method we develop has potential to provide substantial insight into the relative contributions of population and individual-level processes to the dynamics of populations in stochastic environments
Drinking and Flying: Does Alcohol Consumption Affect the Flight and Echolocation Performance of Phyllostomid Bats?
In the wild, frugivorous and nectarivorous bats often eat fermenting fruits and nectar, and thus may consume levels of ethanol that could induce inebriation. To understand if consumption of ethanol by bats alters their access to food and general survival requires examination of behavioural responses to its ingestion, as well as assessment of interspecific variation in those responses. We predicted that bats fed ethanol would show impaired flight and echolocation behaviour compared to bats fed control sugar water, and that there would be behavioural differences among species. (Chiroptera, Phyllostomidae) sugar water (44 g of table sugar in 500 ml of water) or sugar water with ethanol before challenging them to fly through an obstacle course while we simultaneously recorded their echolocation calls. We used bat saliva, a non-invasive proxy, to measure blood ethanol concentrations ranging from 0 to >0.3% immediately before flight trials. Flight performance and echolocation behaviour were not significantly affected by consumption of ethanol, but species differed in their blood alcohol concentrations after consuming it.The bats we studied display a tolerance for ethanol that could have ramifications for the adaptive radiation of frugivorous and nectarivorous bats by allowing them to use ephemeral food resources over a wide span of time. By sampling across phyllostomid genera, we show that patterns of apparent ethanol tolerance in New World bats are broad, and thus may have been an important early step in the evolution of frugivory and nectarivory in these animals
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