533 research outputs found
Magnetic nanoparticles as efficient bulk pinning centers in type-II superconductors
Enhancement of flux pinning by magnetic nanoparticles embedded into the bulk
of type-2 superconductor is studied both theoretically and experimentally.
Magnetic part of the pinning force associated with the interaction between a
spherical magnetic inclusion and an Abrikosov vortex was calculated in the
London approximation. Calculations are supported by the experimental results
obtained on sonochemically modified MgB2 superconductor with embedded magnetic
Fe2O3 nanoparticles and compared to MgB2 with nonmagnetic Mo2O5 pinning centers
of similar concentration and particle size distribution. It is shown that
ferromagnetic nanoparticles result in a considerable enhancement of vortex
pinning in large-kappa type-2 superconductors.Comment: PDF, 14 page
Superfluid fraction in an interacting spatially modulated Bose-Einstein condensate
At zero temperature, a Galilean-invariant Bose fluid is expected to be fully
superfluid. Here we investigate theoretically and experimentally the quenching
of the superfluid density of a dilute Bose-Einstein condensate due to the
breaking of translational (and thus Galilean) invariance by an external 1D
periodic potential. Both Leggett's bound fixed by the knowledge of the total
density and the anisotropy of the sound velocity provide a consistent
determination of the superfluid fraction. The use of a large-period lattice
emphasizes the important role of two-body interactions on superfluidity
Insight from PREFACE & AWA on Tropical Atlantic Tuna ecology and effects on western African fisheries economies
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Novel genomic island modifies DNA with 7-deazaguanine derivatives
The discovery of âŒ20-kb gene clusters containing a family of paralogs of tRNA guanosine transglycosylase genes, called tgtA5, alongside 7-cyano-7-deazaguanine (preQ[subscript 0]) synthesis and DNA metabolism genes, led to the hypothesis that 7-deazaguanine derivatives are inserted in DNA. This was established by detecting 2â-deoxy-preQ[subscript 0] and 2â-deoxy-7-amido-7-deazaguanosine in enzymatic hydrolysates of DNA extracted from the pathogenic, Gram-negative bacteria Salmonella enterica serovar Montevideo. These modifications were absent in the closely related S. enterica serovar Typhimurium LT2 and from a mutant of S. Montevideo, each lacking the gene cluster. This led us to rename the genes of the S. Montevideo cluster as dpdA-K for 7-deazapurine in DNA. Similar gene clusters were analyzed in âŒ150 phylogenetically diverse bacteria, and the modifications were detected in DNA from other organisms containing these clusters, including Kineococcus radiotolerans, Comamonas testosteroni, and Sphingopyxis alaskensis. Comparative genomic analysis shows that, in Enterobacteriaceae, the cluster is a genomic island integrated at the leuX locus, and the phylogenetic analysis of the TgtA5 family is consistent with widespread horizontal gene transfer. Comparison of transformation efficiencies of modified or unmodified plasmids into isogenic S. Montevideo strains containing or lacking the cluster strongly suggests a restrictionâmodification role for the cluster in Enterobacteriaceae. Another preQ[subscript 0] derivative, 2â-deoxy-7-formamidino-7-deazaguanosine, was found in the Escherichia coli bacteriophage 9g, as predicted from the presence of homologs of genes involved in the synthesis of the archaeosine tRNA modification. These results illustrate a deep and unexpected evolutionary connection between DNA and tRNA metabolism.Deutsche ForschungsgemeinschaftSingapore-MIT Alliance in Research and Technology (SMART
Dusty core disease (DuCD): expanding morphological spectrum of RYR1 recessive myopathies
Several morphological phenotypes have been associated to RYR1-recessive myopathies. We recharacterized the RYR1-recessive morphological spectrum by a large monocentric study performed on 54 muscle biopsies from a large cohort of 48 genetically confirmed patients, using histoenzymology, immunohistochemistry, and ultrastructural studies. We also analysed the level of RyR1 expression in patients' muscle biopsies. We defined "dusty cores" the irregular areas of myofibrillar disorganisation characterised by a reddish-purple granular material deposition with uneven oxidative stain and devoid of ATPase activity, which represent the characteristic lesion in muscle biopsy in 54% of patients. We named Dusty Core Disease (DuCD) the corresponding entity of congenital myopathy. Dusty cores had peculiar histological and ultrastructural characteristics compared to the other core diseases. DuCD muscle biopsies also showed nuclear centralization and type1 fibre predominance. Dusty cores were not observed in other core myopathies and centronuclear myopathies. The other morphological groups in our cohort of patients were: Central Core (CCD: 21%), Core-Rod (C&R:15%) and Type1 predominance "plus" (T1P+:10%). DuCD group was associated to an earlier disease onset, a more severe clinical phenotype and a lowest level of RyR1 expression in muscle, compared to the other groups. Variants located in the bridge solenoid and the pore domains were more frequent in DuCD patients. In conclusion, DuCD is the most frequent histopathological presentation of RYR1-recessive myopathies. Dusty cores represent the unifying morphological lesion among the DuCD pathology spectrum and are the morphological hallmark for the recessive form of disease
Quantum character varieties and braided module categories
We compute quantum character varieties of arbitrary closed surfaces with
boundaries and marked points. These are categorical invariants of a surface , determined by the choice of a braided tensor category
, and computed via factorization homology.
We identify the algebraic data governing marked points and boundary
components with the notion of a {\em braided module category} for ,
and we describe braided module categories with a generator in terms of certain
explicit algebra homomorphisms called {\em quantum moment maps}. We then show
that the quantum character variety of a decorated surface is obtained from that
of the corresponding punctured surface as a quantum Hamiltonian reduction.
Characters of braided -modules are objects of the torus category
. We initiate a theory of character sheaves for quantum
groups by identifying the torus integral of
with the category of equivariant quantum
-modules. When , we relate the mirabolic version of this
category to the representations of the spherical double affine Hecke algebra
(DAHA) .Comment: 33 pages, 5 figures. Final version, to appear in Sel. Math. New Se
Nanocomposites with functionalised polysaccharide nanocrystals through aqueous free radical polymerisation promoted by ozonolysis
Cellulose nanocrystals (CNC) and starch nanocrystals (SNC) were grafted by ozone-initiated free-radical polymerisation of styrene in a heterogeneous medium. Surface functionalisation was confirmed by infrared spectroscopy, contact angle measurements, and thermogravimetric and elemental analysis. X-ray diffraction and scanning electron microscopy showed that there was no significant change in the morphology or crystallinity of the nanoparticles following ozonolysis. The grafting efficiency, quantified by 13C NMR, was greater for SNC, with a styrene/anhydroglucose ratio of 1.56 compared to 0.25 for CNC. The thermal stability improved by 100 °C. The contact angles were 97° and 78° following the SNC and CNC grafting, respectively, demonstrating the efficiency of the grafting in changing the surface properties even at low levels of surface substitution. The grafting increased the compatibility with the polylactide, and produced nanocomposites with improved water vapour barrier properties. Ozone-mediated grafting is thus a promising approach for surface functionalisation of polysaccharide nanocrystals
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