7,757 research outputs found

    Types of American Grasses

    Get PDF
    n/

    Differential expression of microRNAs in bovine papillomavirus type 1 transformed equine cells

    Get PDF
    Bovine papillomavirus (BPV) types 1 and 2 play an important role in the pathogenesis of equine sarcoids (ES), the most common cutaneous tumour affecting horses. MicroRNAs (miRNAs), small non-coding RNAs that regulate essential biological and cellular processes, have been found dysregulated in a wide range of tumours. The aim of this study was to identify miRNAs associated with ES. Differential expression of miRNAs was assessed in control equine fibroblasts (EqPalFs) and EqPalFs transformed with the BPV-1 genome (S6-2 cells). Using a commercially available miRNA microarray, 492 mature miRNAs were interrogated. In total, 206 mature miRNAs were differentially expressed in EqPalFs compared with S6-2 cells. Aberrant expression of these miRNAs in S6-2 cells can be attributed to the presence of BPV-1 genomes. Furthermore, we confirm the presence of 124 miRNAs previously computationally predicted in the horse. Our data supports the involvement of miRNAs in the pathogenesis of ES

    Receipt from New York Botanical Gardens to Ogden Goelet

    Get PDF
    https://digitalcommons.salve.edu/goelet-personal-expenses/1038/thumbnail.jp

    Is Improving Access to University Enough? Socio-Economic Gaps in the Earnings of English Graduates

    Get PDF
    Much research and policy attention has been on socio-economic gaps in participation at university, but less attention has been paid to socio-economic gaps in graduates' earnings. This paper addresses this shortfall using tax and student loan administrative data to investigate the variation in earnings of English graduates by socio-economic background. We fi nd that graduates from higher income families (with median income of around 77,000)haveaverageearningswhichare2077,000) have average earnings which are 20% higher than those from lower income families (with median income of around 26,000). Once we condition on institution and subject choices, this premium roughly halves, to around 10%. The premium grows with age and is larger for men, in particular for men at the most selective universities. We estimate the extent to which different institutions and subjects appear to deliver good earnings for relatively less well off students, highlighting the good performance of medicine, economics, law, business, engineering, technology and computer science, as well as the prominent London-based universities.Nuffield Foundation British Academ

    Study of a Large NaI(Tl) Crystal

    Full text link
    Using a narrow band positron beam, the response of a large high-resolution NaI(Tl) crystal to an incident positron beam was measured. It was found that nuclear interactions cause the appearance of additional peaks in the low energy tail of the deposited energy spectrum

    High Purity Pion Beam at TRIUMF

    Full text link
    An extension of the TRIUMF M13 low-energy pion channel designed to suppress positrons based on an energy-loss technique is described. A source of beam channel momentum calibration from the decay pi+ --> e+ nu is also described.Comment: 5 page

    Effects of Contact Network Models on Stochastic Epidemic Simulations

    Full text link
    The importance of modeling the spread of epidemics through a population has led to the development of mathematical models for infectious disease propagation. A number of empirical studies have collected and analyzed data on contacts between individuals using a variety of sensors. Typically one uses such data to fit a probabilistic model of network contacts over which a disease may propagate. In this paper, we investigate the effects of different contact network models with varying levels of complexity on the outcomes of simulated epidemics using a stochastic Susceptible-Infectious-Recovered (SIR) model. We evaluate these network models on six datasets of contacts between people in a variety of settings. Our results demonstrate that the choice of network model can have a significant effect on how closely the outcomes of an epidemic simulation on a simulated network match the outcomes on the actual network constructed from the sensor data. In particular, preserving degrees of nodes appears to be much more important than preserving cluster structure for accurate epidemic simulations.Comment: To appear at International Conference on Social Informatics (SocInfo) 201

    Spatial and spatio-temporal patterns in a cell-haptotaxis model

    Get PDF
    We investigate a cell-haptotaxis model for the generation of spatial and spatio-temporal patterns in one dimension. We analyse the steady state problem for specific boundary conditions and show the existence of spatially hetero-geneous steady states. A linear analysis shows that stability is lost through a Hopf bifurcation. We carry out a nonlinear multi-time scale perturbation procedure to study the evolution of the resulting spatio-temporal patterns. We also analyse the model in a parameter domain wherein it exhibits a singular dispersion relation
    corecore