247 research outputs found
The Rocketdyne Multifunction Tester. Part 2: Operation of a Radial Magnetic Bearing as an Excitation Source
The operation of the magnetic bearing used as an excitation source in the Rocketdyne Multifunction Tester is described. The tester is scheduled for operation during the summer of 1990. The magnetic bearing can be used in two control modes: (1) open loop mode, in which the magnetic bearing operates as a force actuator; and (2) closed loop mode, in which the magnetic bearing provides shaft support. Either control mode can be used to excite the shaft; however, response of the shaft in the two control modes is different due to the alteration of the eigenvalues by closed loop mode operation. A rotordynamic model is developed to predict the frequency response of the tester due to excitation in either control mode. Closed loop mode excitation is shown to be similar to the excitation produced by a rotating eccentricity in a conventional bearing. Predicted frequency response of the tester in the two control modes is compared, and the maximum response is shown to be the same for the two control modes when synchronous unbalance loading is not considered. The analysis shows that the response of this tester is adequate for the extraction of rotordynamic stiffness, damping, and inertia coefficients over a wide range of test article stiffnesses
Suppression of Subsynchronous Vibration in the SSME HPFTP
Space Shuttle Main Engine (SSME) High Pressure Fuel Turbopump (HPFTP) hot-fire dynamic data evaluation and rotordynamic analysis both confirm that two of the most significant turbopump attributes in determining susceptibility to subsynchronous vibration are impeller interstage seal configuration and rotor sideload resulting from turbine turnaround duct configuration and hot gas manifold. Recent hot-fire testing has provided promising indications that the incorporation of roughened damping seals at the impeller interstages may further increase the stability margin of this machine. A summary of the analysis which led to the conclusion that roughened seals would enhance the stability margin is presented along with a correlation of the analysis with recent test data
Cryogenic Fluid Film Bearing Tester Development Study
Conceptual designs were developed for the determination of rotordynamic coefficients of cryogenic fluid film bearings. The designs encompassed the use of magnetic and conventional excitation sources as well as the use of magnetic bearings as support bearings. Test article configurations reviewed included overhung, floating housing, and fixed housing. Uncertainty and forced response analyses were performed to assess quality of data and suitability of each for testing a variety of fluid film bearing designs. Development cost and schedule estimates were developed for each design. Facility requirements were reviewed and compared with existing MSFC capability. The recommended configuration consisted of a fixed test article housing centrally located between two magnetic bearings. The magnetic bearings would also serve as the excitation source
Non-biological methods for phosphorus and nitrogen removal from wastewater: A gap analysis of reinvented-toilet technologies with respect to ISO 30500 [version 1; peer review: 2 approved, 1 not approved]
The aims of the Reinvent the Toilet Challenge (RTTC) include creation of an off-the-grid sanitation system with operating costs of less than US$0.05 per user per day. Because of the small scale at which many reinvented toilets (RT) are intended to operate, non-biological treatment has been generally favored. The RTTC has already instigated notable technological advances in non-sewered sanitation systems (NSSS). However, increasingly stringent effluent standards for N and P could limit the deployment of current RT in real-world scenarios, despite the urgent need for these systems. The newly adopted ISO 30500 standards for water reuse in NSSS dictate minimal use of chemical/biological additives, while at the same time requiring a 70% and 80% reduction in total nitrogen and phosphorus, respectively. This document provides a brief overview of the mature and emerging technologies for N and P removal from wastewater. At present, the dearth of nutrient removal methods proven to be effective at small scales is a significant barrier to meeting ISO 30500 standards. Closing the gap between RTs and ISO 30500 will require significant investments in basic R&D of emerging technologies for non-biological N and P remediation and/or increased reliance on biological processes. Adaptation of existing nutrient-removal technologies to small-scale NSSS is a viable option that merits additional investigation
Improving energy efficiency of electrochemical blackwater disinfection through sequential reduction of suspended solids and chemical oxygen demand [version 2; referees: 2 approved]
Onsite reuse of blackwater requires removal of considerable amounts of suspended solids and organic material in addition to inactivation of pathogens. Previously, we showed that electrochemical treatment could be used for effective pathogen inactivation in blackwater, but was inadequate to remove solids and organics to emerging industry standards. Further, we found that as solids and organics accumulate with repeated recycling, electrochemical treatment becomes less energetically sustainable. Here, we describe a pilot study in which concentrated blackwater is pretreated with ultrafiltration and granular activated carbon prior to electrochemical disinfection, and show that this combination of treatments removes 75-99% of chemical oxygen demand, 92-100% of total suspended solids, and improves the energy efficiency of electrochemical blackwater treatment by an order of magnitude
Improving energy efficiency of electrochemical blackwater disinfection through sequential reduction of suspended solids and chemical oxygen demand [version 1; referees: 2 approved]
Onsite reuse of blackwater requires removal of considerable amounts of suspended solids and organic material in addition to inactivation of pathogens. Previously, we showed that electrochemical treatment could be used for effective pathogen inactivation in blackwater, but was inadequate to remove solids and organics to emerging industry standards. Further, we found that as solids and organics accumulate with repeated recycling, electrochemical treatment becomes less energetically sustainable. Here, we describe a pilot study in which concentrated blackwater is pretreated with ultrafiltration and granular activated carbon prior to electrochemical disinfection, and show that this combination of treatments removes 75-99% of chemical oxygen demand, 92-100% of total suspended solids, and improves the energy efficiency of electrochemical blackwater treatment by an order of magnitude
The Assessment of Fecal Volatile Organic Compounds in Healthy Infants: Electronic Nose Device Predicts Patient Demographics and Microbial Enterotype
Background: The assessment of fecal volatile organic compounds (VOCs) has emerged as a noninvasive biomarker in many different pathologies. Before assessing whether VOCs can be used to diagnose intestinal diseases, including necrotizing enterocolitis (NEC), it is necessary to measure the impact of variable infant demographic factors on VOC signals.
Materials and methods: Stool samples were collected from term infants at four hospitals in a large metropolitan area. Samples were heated, and fecal VOCs assessed by the Cyranose 320 Electronic Nose. Twenty-eight sensors were combined into an overall smellprint and were also assessed individually. 16s rRNA gene sequencing was used to categorize infant microbiomes. Smellprints were correlated to feeding type (formula versus breastmilk), sex, hospital of birth, and microbial enterotype. Overall smellprints were assessed by PERMANOVA with Euclidean distances, and individual sensors from each smellprint were assessed by Mann-Whitney U-tests. P < 0.05 was significant.
Results: Overall smellprints were significantly different according to diet. Individual sensors were significantly different according to sex and hospital of birth, but overall smellprints were not significantly different. Using a decision tree model, two individual sensors could reliably predict microbial enterotype.
Conclusions: Assessment of fecal VOCs with an electronic nose is impacted by several demographic characteristics of infants and can be used to predict microbiome composition. Further studies are needed to design appropriate algorithms that are able to predict NEC based on fecal VOC profiles
The Ensemble Photometric Variability of ~25000 Quasars in the Sloan Digital Sky Survey
Using a sample of over 25000 spectroscopically confirmed quasars from the
Sloan Digital Sky Survey, we show how quasar variability in the rest frame
optical/UV regime depends upon rest frame time lag, luminosity, rest
wavelength, redshift, the presence of radio and X-ray emission, and the
presence of broad absorption line systems. The time dependence of variability
(the structure function) is well-fit by a single power law on timescales from
days to years. There is an anti-correlation of variability amplitude with rest
wavelength, and quasars are systematically bluer when brighter at all
redshifts. There is a strong anti-correlation of variability with quasar
luminosity. There is also a significant positive correlation of variability
amplitude with redshift, indicating evolution of the quasar population or the
variability mechanism. We parameterize all of these relationships. Quasars with
RASS X-ray detections are significantly more variable (at optical/UV
wavelengths) than those without, and radio loud quasars are marginally more
variable than their radio weak counterparts. We find no significant difference
in the variability of quasars with and without broad absorption line troughs.
Models involving multiple discrete events or gravitational microlensing are
unlikely by themselves to account for the data. So-called accretion disk
instability models are promising, but more quantitative predictions are needed.Comment: 41 pages, 21 figures, AASTeX, Accepted for publication in Ap
Analysis of changing statistical significance from .05 to .005 in foot and ankle randomized controlled trials
Background: Misinterpretation of p-values in RCTs is extremely problematic since they are the core basis for high levels of recommendation in clinical practice guidelines, especially Orthopaedics. Benjamin et al. proposed a universal protocol change, moving statistical significance from a p-value of .05 to .005 to combat the misinterpretation that is happening in medical literature. In this study, we are looking to evaluate the effect of the protocol suggested by Benjamin et al. on foot and ankle-related RCTs in the top 3 Foot and Ankle-related journals.Methods: We conducted a Pubmed search looking at studies published from January 1st, 2016 to November 10, 2021, in the following three journals; Foot and Ankle International, Journal of Foot and Ankle Surgery, and Foot & Ankle International. The inclusion criteria for the study were RCTs published in the above journals with specifically stated primary endpoints. If a study has multiple primary endpoints, all were included. Exclusion criteria were any study that was not prospective and randomized by design, also any study that did not state primary endpoints was excluded. Two authors extracted the data using a pilot-tested Google form, any disagreements or questions were resolved by published methodologic orthopaedic authors.Results: Of the 222 endpoints, 101 endpoints (45.5%; 101/222) were at or below the .05 threshold while 121 endpoints (54.5%; 121/222) were above the .05 threshold. We also found that 59 endpoints (26.6%; 59/222) were below .005.Conclusion: Our results suggest that changing the threshold for statistical significance from .05 to .005 in foot and ankle RCTs would heavily alter literature published in the field. By implementing this methodology, it is a promising measure to be able to increase RCT quality until a more substantial solution can be found. With that being said, caution must be taken when interpreting our results, also requiring further evaluation
Metabolic flexibility as a major predictor of spatial distribution in microbial communities
A better understand the ecology of microbes and their role in the global ecosystem could be achieved if traditional ecological theories can be applied to microbes. In ecology organisms are defined as specialists or generalists according to the breadth of their niche. Spatial distribution is often used as a proxy measure of niche breadth; generalists have broad niches and a wide spatial distribution and specialists a narrow niche and spatial distribution. Previous studies suggest that microbial distribution patterns are contrary to this idea; a microbial generalist genus (Desulfobulbus) has a limited spatial distribution while a specialist genus (Methanosaeta) has a cosmopolitan distribution. Therefore, we hypothesise that this counter-intuitive distribution within generalist and specialist microbial genera is a common microbial characteristic. Using molecular fingerprinting the distribution of four microbial genera, two generalists, Desulfobulbus and the methanogenic archaea Methanosarcina, and two specialists, Methanosaeta and the sulfate-reducing bacteria Desulfobacter were analysed in sediment samples from along a UK estuary. Detected genotypes of both generalist genera showed a distinct spatial distribution, significantly correlated with geographic distance between sites. Genotypes of both specialist genera showed no significant differential spatial distribution. These data support the hypothesis that the spatial distribution of specialist and generalist microbes does not match that seen with specialist and generalist large organisms. It may be that generalist microbes, while having a wider potential niche, are constrained, possibly by intrageneric competition, to exploit only a small part of that potential niche while specialists, with far fewer constraints to their niche, are more capable of filling their potential niche more effectively, perhaps by avoiding intrageneric competition. We suggest that these counter-intuitive distribution patterns may be a common feature of microbes in general and represent a distinct microbial principle in ecology, which is a real challenge if we are to develop a truly inclusive ecology
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