118 research outputs found
Building Health Literacy and Cultural Competency Through Video Recording Exercises
Video creation skills would allow pharmacists to create content tailored to their patients’ needs and include relevant aspects of cultural competency to achieve the goal of improved health literacy. Video recording exercises can provide students with an opportunity to build their drug knowledge and health literacy skills.
Conflict of Interest
None
Type: Commentar
Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance
Mph1 is a member of the conserved FANCM family of DNA motor proteins that play key roles in genome maintenance
processes underlying Fanconi anemia, a cancer predisposition syndrome in humans. Here, we identify Mte1
as a novel interactor of the Mph1 helicase in Saccharomyces cerevisiae. In vitro, Mte1 (Mph1-associated telomere
maintenance protein 1) binds directly to DNA with a preference for branched molecules such as D loops and fork
structures. In addition, Mte1 stimulates the helicase and fork regression activities of Mph1 while inhibiting the
ability of Mph1 to dissociate recombination intermediates. Deletion of MTE1 reduces crossover recombination and
suppresses the sensitivity of mph1Δ mutant cells to replication stress. Mph1 and Mte1 interdependently colocalize
atDNAdamage-induced foci and dysfunctional telomeres, and MTE1 deletion results in elongated telomeres. Taken
together, our data indicate that Mte1 plays a role in regulation of crossover recombination, response to replication
stress, and telomere maintenance
Improving the Tenure Committee's Review Efficiency with Embedded Dossier Functionality
Numerous manuscripts have been published addressing perceptions of the promotion and tenure process. Very little has been published on mechanism to improve the efficiency of dossier review or tools to assist the reviewer in understanding the comprehensive scope of the applicant’s experiences. An innovative dossier format was utilized to assess the hyperlinks and pop-up tool tips would enhance the reviewer efficiency when reviewing the applicant’s materials. Super scripted numbers at the end of the narrative’s sentences, in the same manner as a journal article, contained the embedded hyperlinks and pop-up tool tips. A majority of the reviewers found the embedded functionality in the dossier did enhance their efficiency in completing the review.
Type: Case Stud
INSTRUCTIONAL DESIGN AND ASSESSMENT Electronic Integration of Prerequisite Course Content
Objectives. To evaluate the effect of electronic integration of embedded prerequisite information (EPI) on student learning. Design. Specific prerequisite information presented in a Chemical Basis of Drug Action course and important to understanding new topics presented in subsequent courses was identified and embedded in online course materials using pop-ups and hyperlinks. Students were encouraged to review the EPI. Assessment. There was no significant difference (P,0.05) between student performance on examination 3, which covered embedded information, and student performance on examination 1 which did not. Employing the Likert scale, a cumulative average of 75% and 87% of the campus and distance students rated the impact of EPI slightly positive to positive, respectively. Conclusion. Although student performance did not improve with the introduction of EPI, both campus and distance students viewed the EPI positively
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