The U.S. household furniture industry: Adapting to changing times.

The U.S. wood household furniture industry has adapted to change in many ways in recent years. The industry has grown steadily since the 1982 recession, and has been shifting to the U.S . South and Southeast. Although California has also become prominent in furniture production, many recent factors indicate geographic shifts away from the state, particularly in wood furniture production. The household furniture industry has also adapted and continues to adapt to factors which have increased the globalization of trade in all products. Foreign competition has resulted in mergers and consolidation in the U.S. household furniture industry, and has also forced production to become more oriented toward non ready-to-assemble and upholstered furniture

The Mississippi furniture industry and its use of wood-based materials

Furniture manufacturing is one of the most important industries in Mississippi; the industry\u27s phenomenal growth and current high levels of production and employment have recently been widely recognized and publicized. The Mississippi Economic Council (1988), for example, recently labeled the state The New Furniture Capital of America;\u27 and Northeast Mississippi was recently described as a booming region\u27\u27 that wants to be the Furniture Capital of America\u27\u27 (Evans 1987). The present report characterizes important aspects of Mississippi\u27s furniture industry, including its development and relative importance within the state and within the U.S., and assesses current information on the availability and use of wood-based raw materials. The report has major sections on The Mississippi Furniture Industry and Use of Wood-Based Materials, with a Discussion section summarizing the current outlook for furniture production and demand

Regions important for the adhesin activity of Moraxella catarrhalis Hag

© 2007 Bullard et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

NASA Light-Emitting Diodes for the Prevention of Oral Mucositis in Pediatric Bone Marrow Transplant Patients

Objective: The purpose of this study was to determine the effects of prophylactic near-infrared light therapy from light-emitting diodes (LEDs) in pediatric bone marrow transplant (BMT) recipients. Background Data: Oral mucositis (OM) is a frequent side effect of chemotherapy that leads to increased morbidity. Near-infrared light has been shown to produce biostimulatory effects in tissues, and previous results using nearinfrared lasers have shown improvement in OM indices. However, LEDs may hold greater potential for clinical applications. Materials and Methods: We recruited 32 consecutive pediatric patients undergoing myeloablative therapy in preparation for BMT. Patients were examined by two of three pediatric dentists trained in assessing the Schubert oral mucositis index (OMI) for left and right buccal and lateral tongue mucosal surfaces, while the patients were asked to rate their current left and right mouth pain, left and right xerostomia, and throat pain. LED therapy consisted of daily treatment at a fluence of 4 J/cm2 using a 670-nm LED array held to the left extraoral epithelium starting on the day of transplant, with a concurrent sham treatment on the right. Patients were assessed before BMT and every 2–3 days through posttransplant day 14. Outcomes included the percentage of patients with ulcerative oral mucositis (UOM) compared to historical epidemiological controls, the comparison of left and right buccal pain to throat pain, and the comparison between sides of the buccal and lateral tongue OMI and buccal pain. Results: The incidence of UOM was 53%, compared to an expected rate of 70–90%. There was also a 48% and 39% reduction of treated left and right buccal pain, respectively, compared to untreated throat pain at about posttransplant day 7 (p \u3c 0.05). There were no significant differences between sides in OMI or pain. Conclusion: Although more studies are needed, LED therapy appears useful in the prevention of OM in pediatric BMT patients

Design and testing of a 96-channel neural interface module for the Networked Neuroprosthesis system

Abstract Background The loss of motor functions resulting from spinal cord injury can have devastating implications on the quality of one’s life. Functional electrical stimulation has been used to help restore mobility, however, current functional electrical stimulation (FES) systems require residual movements to control stimulation patterns, which may be unintuitive and not useful for individuals with higher level cervical injuries. Brain machine interfaces (BMI) offer a promising approach for controlling such systems; however, they currently still require transcutaneous leads connecting indwelling electrodes to external recording devices. While several wireless BMI systems have been designed, high signal bandwidth requirements limit clinical translation. Case Western Reserve University has developed an implantable, modular FES system, the Networked Neuroprosthesis (NNP), to perform combinations of myoelectric recording and neural stimulation for controlling motor functions. However, currently the existing module capabilities are not sufficient for intracortical recordings. Methods Here we designed and tested a 1 × 4 cm, 96-channel neural recording module prototype to fit within the specifications to mate with the NNP. The neural recording module extracts power between 0.3–1 kHz, instead of transmitting the raw, high bandwidth neural data to decrease power requirements. Results The module consumed 33.6 mW while sampling 96 channels at approximately 2 kSps. We also investigated the relationship between average spiking band power and neural spike rate, which produced a maximum correlation of R = 0.8656 (Monkey N) and R = 0.8023 (Monkey W). Conclusion Our experimental results show that we can record and transmit 96 channels at 2ksps within the power restrictions of the NNP system and successfully communicate over the NNP network. We believe this device can be used as an extension to the NNP to produce a clinically viable, fully implantable, intracortically-controlled FES system and advance the field of bioelectronic medicine.https://deepblue.lib.umich.edu/bitstream/2027.42/147921/1/42234_2019_Article_19.pd

Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin\u27s I-band: the cardiomyopathy-linked mutation T2580I

Missense single-nucleotide polymorphisms (mSNPs) in titin are emerging as a main causative factor of heart failure. However, distinguishing between benign and disease-causing mSNPs is a substantial challenge. Here, we research the question of whether a single mSNP in a generic domain of titin can affect heart function as a whole and, if so, how. For this, we studied the mSNP T2850I, seemingly linked to arrhythmogenic right ventricular cardiomyopathy (ARVC). We used structural biology, computational simulations and transgenic muscle in vivo methods to track the effect of the mutation from the molecular to the organismal level. The data show that the T2850I exchange is compatible with the domain three-dimensional fold, but that it strongly destabilizes it. Further, it induces a change in the conformational dynamics of the titin chain that alters its reactivity, causing the formation of aberrant interactions in the sarcomere. Echocardiography of knock-in mice indicated a mild diastolic dysfunction arising from increased myocardial stiffness. In conclusion, our data provide evidence that single mSNPs in titin\u27s I-band can alter overall muscle behaviour. Our suggested mechanisms of disease are the development of non-native sarcomeric interactions and titin instability leading to a reduced I-band compliance. However, understanding the T2850I-induced ARVC pathology mechanistically remains a complex problem and will require a deeper understanding of the sarcomeric context of the titin region affected

Complementary and alternative medicine for mental disorders among African Americans, black Caribbeans, and whites.

OBJECTIVES: This study examined racial and ethnic differences in the use of complementary and alternative medicine (CAM) for the treatment of mental and substance use disorders. METHODS: Data were from the National Survey of American Life (NSAL) and the National Comorbidity Survey-Replication (NCS-R). The analytic sample included 631 African Americans and 245 black Caribbeans from the NSAL and 1,393 non-Hispanic whites from the NCS-R who met criteria for a mood, anxiety, or substance use disorder in the past 12 months. Logistic regression was used to examine racial and ethnic differences in the use of any CAM and in the use of CAM only versus the use of CAM plus services in another treatment sector. RESULTS: Thirty-four percent of respondents used some form of CAM. Whites were more likely than blacks to use any CAM, although there was no racial or ethnic difference in CAM use only versus CAM use plus traditional services. A higher proportion of blacks than whites used prayer and other spiritual practices. Among those with a mood disorder, black Caribbeans were less likely than African Americans to use any CAM. CONCLUSIONS: Findings of this study were similar to those of previous studies that examined physical illness in relation to CAM use in terms of its overall prevalence, the predominant use of CAM in conjunction with traditional service providers, and racial and ethnic differences in the use of CAM. The use of prayer was a major factor in differences between blacks and whites in CAM use; however, there were also differences among black Americans that warrant further research.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/78173/1/1342.pd

Exposures to Air Pollutants during Pregnancy and Preterm Delivery

The association between preterm delivery (PTD) and exposure to air pollutants has recently become a major concern. We investigated this relationship in Incheon, Republic of Korea, using spatial and temporal modeling to better infer individual exposures. The birth cohort consisted of 52,113 singleton births in 2001–2002, and data included residential address, gestational age, sex, birth date and order, and parental age and education. We used a geographic information system and kriging methods to construct spatial and temporal exposure models. Associations between exposure and PTD were evaluated using univariate and multivariate log-binomial regressions. Given the gestational age, birth date, and the mother’s residential address, we estimated each mother’s potential exposure to air pollutants during critical periods of the pregnancy. The adjusted risk ratios for PTD in the highest quartiles of the first trimester exposure were 1.26 [95% confidence interval (CI), 1.11–1.44] for carbon monoxide, 1.27 (95% CI, 1.04–1.56) for particulate matter with aerodynamic diameter ≤ 10 μm, 1.24 (95% CI, 1.09–1.41) for nitrogen dioxide, and 1.21 (95% CI, 1.04–1.42) for sulfur dioxide. The relationships between PTD and exposures to CO, NO(2), and SO(2) were dose dependent (p < 0.001, p < 0.02, p < 0.02, respectively). In addition, the results of our study indicated a significant association between air pollution and PTD during the third trimester of pregnancy. In conclusion, our study showed that relatively low concentrations of air pollution under current air quality standards during pregnancy may contribute to an increased risk of PTD. A biologic mechanism through increased prostaglandin levels that are triggered by inflammatory mediators during exposure periods is discussed

Large-Scale Asset Purchases by the Federal Reserve: Did They Work?

Discusses how the Federal Reserve faced the challenge to further ease the stance of monetary policy as the economic outlook deteriorated through LSAPs

Submersible study of an oceanic megamullion in the central North Atlantic

Author Posting. © American Geophysical Union, 2001. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research 106, no. B8 (2001): 16145–16161, doi:10.1029/2001JB000373.Recently discovered megamullions on the seafloor have been interpreted to be the exhumed footwalls of long-lived detachment faults operating near the ends of spreading segments in slow spreading crust. We conducted five submersible dives on one of these features just east of the rift valley in the Mid-Atlantic Ridge at 26°35′N and obtained visual, rock sample, gravity, and heat flow data along a transect from the breakaway zone (where the fault is interpreted to have first nucleated in ∼2.0–2.2 Ma crust) westward to near the termination (∼0.7 Ma). Our observations are consistent with the detachment fault hypothesis and show the following features. In the breakaway zone, faulted and steeply backtilted basaltic blocks suggest rotation above a deeper shear zone; the youngest normal faults in this sequence are interpreted to have evolved into the long-lived detachment fault. In younger crust the interpreted detachment surface rises as monotonously flat seafloor in a pair of broad, gently sloping domes that formed simultaneously along isochrons and are now thinly covered by sediment. The detachment surface is locally littered with basaltic debris that may have been clipped from the hanging wall. The domes coincide with a gravity high that continues along isochrons within the spreading segment. Modeling of on-bottom gravity measurements and recovery of serpentinites imply that mantle rises steeply and is exposed within ∼7 km west of the breakaway but that rocks with intermediate densities prevail farther west. Within ∼5 km of the termination, small volcanic cones appear on the detachment surface, indicating melt input into the footwall. We interpret the megamullion to have developed during a phase of limited magmatism in the spreading segment, with mantle being exhumed by the detachment fault <0.5 m.y. after its initiation. Increasing magmatism may eventually have weakened the lithosphere and facilitated propagation of a rift that terminated slip on the detachment fault progressively between ∼1.3 m.y. and 0.7 m.y. Identifiable but low-amplitude magnetic anomalies over the megamullion indicate that it incorporates a magmatic component. We infer that much of the footwall is composed of variably serpentinized peridotite intruded by plutons and dikes.B. Tucholke's research was supported by NSF grant OCE-9503561 and by an award from the Andrew W. Mellon Foundation Endowed Fund for Innovative Research and the Henry Bryant Bigelow Chair in Oceanography at Woods Hole Oceanographic Institution. G. Hirth acknowledges support by NSF grant OCE-9907244