Thermal Conductivity and Specific Heat of the Spin-Ice Compound Dy2_2Ti2_2O7_7: Experimental Evidence for Monopole Heat Transport

Elementary excitations in the spin-ice compound Dy$_2$Ti$_2$O$_7$ can be described as magnetic monopoles propagating independently within the pyrochlore lattice formed by magnetic Dy ions. We studied the magnetic-field dependence of the thermal conductivity {\kappa}(B) for B || [001] and observe clear evidence for magnetic heat transport originating from the monopole excitations. The magnetic contribution {\kappa}_{mag} is strongly field-dependent and correlates with the magnetization M(B). The diffusion coefficient obtained from the ratio of {\kappa}_{mag} and the magnetic specific heat is strongly enhanced below 1 K indicating a high mobility of the monopole excitations in the spin-ice state.Comment: 5 pages, 4 figure

Substitution effects on the temperature vs. magnetic-field phase diagrams of the quasi-1D effective Ising spin-1/2 chain system BaCo2_2V2_2O8_8

BaCo$_2$V$_2$O$_8$ is a one-dimensional antiferromagnetic spin-1/2 chain system with pronounced Ising anisotropy of the magnetic exchange. Due to finite interchain interactions long-range antiferromagnetic order develops below $T_{\rm N} \simeq 5.5$ K, which is accompanied by a structural distortion in order to lift magnetic frustration effects. The corresponding temperature $vs.$ magnetic-field phase diagram is highly anisotropic with respect to the magnetic-field direction and various details are still under vivid discussion. Here, we report the influence of several substitutions on the magnetic properties and the phase diagrams of BaCo$_2$V$_2$O$_8$. We investigate the substitution series Ba$_{\text{1-x}}$Sr$_{\text{x}}$Co$_{\text{2}}$V$_{\text{2}}$O$_{\text{8}}$ over the full range $0\le x \le 1$ as well as the influence of a partial substitution of the magnetic Co$^{2+}$ by small amounts of other magnetic transition metals or by non-magnetic magnesium. In all cases, the phase diagrams were obtained on single crystals from magnetization data and/or high-resolution studies of the thermal expansion and magnetostriction.Comment: 10 pages, 10 figure

Low-temperature ordered phases of the spin-12\frac{1}{2} XXZ chain system Cs2_2CoCl4_4

In this study the magnetic order of the spin-1/2 XXZ chain system Cs$_2$CoCl$_4$ in a temperature range from 50 mK to 0.5 K and in applied magnetic fields up to 3.5 T is investigated by high-resolution measurements of the thermal expansion and the specific heat. Applying magnetic fields along a or c suppresses $T_\textrm{N}$ completely at about 2.1 T. In addition, we find an adjacent intermediate phase before the magnetization saturates close to 2.5 T. For magnetic fields applied along b, a surprisingly rich phase diagram arises. Two additional transitions are observed at critical fields $\mu_0 H_{SF1}\simeq 0.25$ T and $\mu_0 H_{SF2}\simeq 0.7$ T, which we propose to arise from a two-stage spin-flop transition.Comment: 10 pages, 10 figure

Cross section measurements on 61Cu for proton beam monitoring above 20 MeV

Introduction All experimental studies involving charged particle induced nuclear reactions require a precise knowledge of monitor reactions. A number of well described proton induced monitor reactions exist in the lower energy range [1], which is covered by most medical cyclotrons. Concerning proton energies above 20 MeV, however, the accuracy of the monitor reactions declines as cross section data becomes scarcer. Furthermore, the growing interest in precise determination of projectile energies by comparing of ratios of monitor reaction cross sections demands new measurements and evaluations of known data for high threshold monitor radionuclides. In this work cross section measurements on the formation of 61Cu were done and energy de-pendent radionuclide ratios were calculated. Material and Methods For investigation of the natCu(p,x)61Cu reaction copper foils of natural isotopic composition (Goodfellow Ltd.) were irradiated. The targets were of 10 and 20 μm thickness, having a diameter of 15 mm. Proton bombardments up to 45 MeV incident energy were done in the stacked-foil arrangement at the accelerator JULIC of the Nuclear Physics Institute (IKP) of the Forschungszentrum Jülich. In addition to an internal irradiation possibility the cyclotron is equipped with an external target station which was used for most experiments. It can adapt standard and slanting solid target holders and is equipped with a water cooled four sector collimator and additional helium cooling of the entry foil. Several irradiations were executed. In each stack, besides copper samples, aluminium absorbers and additional nickel monitor foils were also placed, the latter for the determination of the respective beam current. The produced radioactivity of 61Cu was analysed non-destructively using HPGe γ-ray detectors (EG&G Ortec). Results and Conclusion Reaction cross sections of the natCu(p,x)61Cu process up to 45 MeV were measured and com-pared with existing data from the literature (FIG. 2). Except for the data of Williams et al. our results are in good agreement, showing a maxi-mum of about 165 mbarn at 37.5 MeV proton energy. The overall uncertainty of the new cross section data is between 8 and 10 %. In FIG. 3, the excitation functions of the relevant monitor reactions on Cu are shown. In combination with the excitation function of the natCu(p,xn)62Zn reaction, isotope ratios were calculated which can be used for determination of the proton energy within a target stack in the energy range of 22–40 MeV as described by Piel et al. [3]. FIGURE 4 shows the cross section ratio in dependence of the proton energy. Above this energy, 65Zn could be used to generate isotope ratios for energy determination, although the long half-life (T½ = 244.3 d) of that radionuclide may be a problem. Additional cross section measurements are planned in order to further strengthen the data base of this potential monitor reaction. The results of this work shall be evaluated in the framework of an ongoing Coordinated Research Project of the IAEA

The spin-12\frac{1}{2} XXZ chain system Cs2_2CoCl4_4 in a transverse magnetic field

Comparing high-resolution specific heat and thermal expansion measurements to exact finite-size diagonalization, we demonstrate that Cs$_2$CoCl$_4$ for a magnetic field along the crystallographic b axis realizes the spin-$\frac{1}{2}$ XXZ chain in a transverse field. Exploiting both thermal as well as virtual excitations of higher crystal field states, we find that the spin chain is in the XY-limit with an anisotropy $J_z/J_\perp \approx 0.12$ substantially smaller than previously believed. A spin-flop Ising quantum phase transition occurs at a critical field of $\mu_0 H_b^{\rm cr} \approx 2$ T before around 3.5 T the description in terms of an effective spin-$\frac{1}{2}$ chain becomes inapplicable.Comment: 5 pages, 3 figure

LOF: Identifying density-based local outliers

For many KDD applications, such as detecting criminal activities in E-commerce, finding the rare instances or the outliers, can be more interesting than finding the common patterns. Existing work in outlier detection regards being an outlier as a binary property. In this paper, we contend that for many scenarios, it is more meaningful to assign to each object a degree of being an outlier. This degree is called the local outlier factor (LOF) of an object. It is local in that the degree depends on how isolated the object is with respect to the surrounding neighborhood. We give a detailed formal analysis showing that LOF enjoys many desirable properties. Using realworld datasets, we demonstrate that LOF can be used to find outliers which appear to be meaningful, but can otherwise not be identified with existing approaches. Finally, a careful performance evaluation of our algorithm confirms we show that our approach of finding local outliers can be practical

LOF: Identifying density-based local outliers

For many KDD applications, such as detecting criminal activities in E-commerce, finding the rare instances or the outliers, can be more interesting than finding the common patterns. Existing work in outlier detection regards being an outlier as a binary property. In this paper, we contend that for many scenarios, it is more meaningful to assign to each object a degree of being an outlier. This degree is called the local outlier factor (LOF) of an object. It is local in that the degree depends on how isolated the object is with respect to the surrounding neighborhood. We give a detailed formal analysis showing that LOF enjoys many desirable properties. Using realworld datasets, we demonstrate that LOF can be used to find outliers which appear to be meaningful, but can otherwise not be identified with existing approaches. Finally, a careful performance evaluation of our algorithm confirms we show that our approach of finding local outliers can be practical

β-Glucuronidase triggers extracellular MMAE release from an integrin-targeted conjugate

A non-internalizing \u3b1v\u3b23 integrin ligand was conjugated to the anticancer drug MMAE through a \u3b2-glucuronidase-responsive linker. In the presence of \u3b2-glucuronidase, only the conjugate bearing a PEG4 spacer inhibited the proliferation of integrin-expressing cancer cells at low nanomolar concentrations, indicating important structural requirements for the efficacy of these therapeutics