Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management

Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the catecholaminergic hypersecretion. Diagnosis involves biochemical tests that reveal elevated levels of catecholamine metabolites (metanephrine and normetanephrine). Functional imaging, such as 123I-metaiodobenzylguanidine scintigraphy (123I-MIBG), has increased specificity in identifying the catecholamine-producing tumor and its metastases. The gold-standard treatment for patients with pheochromocytoma is represented by the surgical removal of the tumor. Before surgical resection, it is important to optimize blood pressure and intravascular volume in order to avoid negative hemodynamic events

A negotiation approach to support interoperability in a collaborative manufacturing environment

Maintaining the interoperability in a dynamic competitive manufacturing environment in which different business enterprises collaborate is difficult to achieve. Our approach highlights negotiation as the best solution to solve interoperability problems by reaching the common decision suitable for all managers of various enterprises in the most optimized amount of time. In this context, this paper proposes a multi-agent negotiation model, able to coordinate several negotiations taking place in parallel among multiple participants. It is described the negotiation strategy for evaluating and generating offers and the protocol for sending the offers to the other agents. This model is being implemented in the H2020 C2NET project for supporting manufacturing.info:eu-repo/semantics/acceptedVersio

Coordinating negotiations in data-intensive collaborative working environments using an agent-based model-driven platform

This paper tackles the interoperability problems of enterprise information systems by presenting a distributive model-driven platform for parallel coordination of multiple negotiations in data-intensive collaborative working environments. The proposed model was validated and verified by an industrial application scenario within the European research project H2020 C2NET (Cloud Collaborative Manufacturing Networks). This real scenario developed data-intensive collaborative and cloud-enabled tools that allow the optimisation of the supply network of manufacturing SMEs, proposing a negotiation solution based on a model-driven interoperable decentralised architecture.info:eu-repo/semantics/acceptedVersio

Highly site-specific H2 adsorption on vicinal Si(001) surfaces

Experimental and theoretical results for the dissociative adsorption of H_2 on vicinal Si(001) surfaces are presented. Using optical second-harmonic generation, sticking probabilities at the step sites are found to exceed those on the terraces by up to six orders of magnitude. Density functional theory calculations indicate the presence of direct adsorption pathways for monohydride formation but with a dramatically lowered barrier for step adsorption due to an efficient rehybridization of dangling orbitals.Comment: 5 pages, 4 figures, submitted to Phys. Rev. Lett. (1998). Other related publications can be found at http://www.fhi-berlin.mpg.de/th/paper.htm

Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management

Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the catecholaminergic hypersecretion. Diagnosis involves biochemical tests that reveal elevated levels of catecholamine metabolites (metanephrine and normetanephrine). Functional imaging, such as 123I-metaiodobenzylguanidine scintigraphy (123I-MIBG), has increased specificity in identifying the catecholamine-producing tumor and its metastases. The gold-standard treatment for patients with pheochromocytoma is represented by the surgical removal of the tumor. Before surgical resection, it is important to optimize blood pressure and intravascular volume in order to avoid negative hemodynamic events

Density-functional study of hydrogen chemisorption on vicinal Si(001) surfaces

Relaxed atomic geometries and chemisorption energies have been calculated for the dissociative adsorption of molecular hydrogen on vicinal Si(001) surfaces. We employ density-functional theory, together with a pseudopotential for Si, and apply the generalized gradient approximation by Perdew and Wang to the exchange-correlation functional. We find the double-atomic-height rebonded D_B step, which is known to be stable on the clean surface, to remain stable on partially hydrogen-covered surfaces. The H atoms preferentially bind to the Si atoms at the rebonded step edge, with a chemisorption energy difference with respect to the terrace sites of >sim 0.1 eV. A surface with rebonded single atomic height S_A and S_B steps gives very similar results. The interaction between H-Si-Si-H mono-hydride units is shown to be unimportant for the calculation of the step-edge hydrogen-occupation. Our results confirm the interpretation and results of the recent H_2 adsorption experiments on vicinal Si surfaces by Raschke and Hoefer described in the preceding paper.Comment: 13 pages, 8 figures, submitted to Phys. Rev. B. Other related publications can be found at http://www.rz-berlin.mpg.de/th/paper.htm

Multidimensional Homeier's generalized class and its application to planar 1D Bratu problem

[EN] In this paper, a parametric family of iterative methods for solving nonlinear systems, including Homeier’s scheme is presented, proving its third-order of convergence. The numerical section is devoted to obtain an estimation of the solution of the classical Bratu problem by transforming it in a nonlinear system by using finite differences, and solving it with different elements of the iterative family.This research was supported by Ministerio de Economía y Competitividad MTM2014-52016-C02-02.Cordero Barbero, A.; Franqués García, AM.; Torregrosa Sánchez, JR. (2015). Multidimensional Homeier's generalized class and its application to planar 1D Bratu problem. Journal of the Spanish Society of Applied Mathematics. 70(1):1-10. https://doi.org/10.1007/s40324-015-0037-xS110701Abad, M. F., Cordero, A., Torregrosa, J. R.: Fourth-and fifth-order for solving nonlinear systems of equations: an application to the global positioning system, Abstr. Appl. Anal. (2013) (Article ID 586708)Andreu, C., Cambil, N., Cordero, A., Torregrosa, J.R.: Preliminary orbit determination of artificial satellites: a vectorial sixth-order approach, Abstr. Appl. Anal. (2013) (Article ID 960582)Awawdeh, F.: On new iterative method for solving systems of nonlinear equations. Numer. Algorithms 54, 395–409 (2010)Boyd, J.P.: One-point pseudospectral collocation for the one-dimensional Bratu equation. Appl. Math. Comput. 217, 5553–5565 (2011)Bratu, G.: Sur les equation integrals non-lineaires. Bull. Math. Soc. France 42, 113–142 (1914)Buckmire, R.: Applications of Mickens finite differences to several related boundary value problems. In: Mickens, R.E. (ed.) Advances in the Applications of Nonstandard Finite Difference Schemes, pp. 47–87. World Scientific Publishing, Singapore (2005)Cordero, A., Hueso, J.L., Martínez, E., Torregrosa, J.R.: A modified Newton-Jarratt’s composition. Numer. Algorithms 55, 87–99 (2010)Gelfand, I.M.: Some problems in the theory of quasi-linear equations. Trans. Am. Math. Soc. Ser. 2, 295–381 (1963)Homeier, H.H.H.: On Newton-tyoe methods with cubic convergence. J. Comput. Appl. Math. 176, 425–432 (2005)Jacobsen, J., Schmitt, K.: The Liouville-Bratu-Gelfand problem for radial operators. J. Differ. Equ. 184, 283–298 (2002)Jalilian, R.: Non-polynomial spline method for solving Bratu’s problem. Comput. Phys. Comm. 181, 1868–1872 (2010)Kanwar, V., Kumar, S., Behl, R.: Several new families of Jarratts method for solving systems of nonlinear equations. Appl. Appl. Math. 8(2), 701–716 (2013)Mohsen, A.: A simple solution of the Bratu problem. Comput. Math. with Appl. 67, 26–33 (2014)Petković, M., Neta, B., Petković, L., Džunić, J.: Multipoint Methods for Solving Nonlinear Equations. Academic Press, Amsterdam (2013)Sharma, J.R., Guna, R.K., Sharma, R.: An efficient fourth order weighted-Newton method for systems of nonlinear equations. Numer. Algorithms 62, 307–323 (2013)Sharma, J.R., Arora, H.: On efficient weighted-Newton methods for solving systems of nonlinear equations. Appl. Math. Comput. 222, 497–506 (2013)Traub, J.F.: Iterative Methods for the Solution of Equations. Chelsea Publishing Company, New York (1982)Wan, Y.Q., Guo, Q., Pan, N.: Thermo-electro-hydrodynamic model for electrospinning process. Int. J. Nonlinear Sci. Numer. Simul. 5, 5–8 (2004

Limited Vitrectomy versus Complete Vitrectomy for Epiretinal Membranes: A Comparative Multicenter Trial

Purpose. To evaluate whether limited vitrectomy is as effective as complete vitrectomy in eyes with epiretinal membrane (ERM) and to compare the surgical times and rates of complications. Methods. In this multicentre European study, data of eyes with ERM that underwent vitrectomy from January 2017 to July 2018 were analyzed retrospectively. In the limited vitrectomy group, a posterior vitreous detachment (PVD) was induced up till the equator as opposed to complete PVD induction till the vitreous base in the comparison group. Incidence of iatrogenic retinal breaks, retinal detachment, surgical time, and visual outcomes were compared between groups. Results. We included 139 eyes in the analysis with a mean age being 72.2 \ub1 6.9 years. In this, sixty-five eyes (47%) underwent limited vitrectomy and 74 eyes (53%) underwent complete vitrectomy. Iatrogenic retinal tears were seen in both groups (5% in limited vitrectomy versus 7% in complete vitrectomy, p=0.49). Retinal detachment occurred in 2 eyes in the limited vitrectomy group (3%) compared to none in the complete vitrectomy group (p=0.22). Best-corrected visual acuity (BCVA) and central macular thickness improved significantly with no intergroup differences (p=0.18). Surgical time was significantly shorter in the limited vitrectomy group with 91% surgeries taking less than 1 hour compared to 71% in the complete vitrectomy group (p<0.001). Conclusion. A limited vitrectomy is a time-efficient and effective surgical procedure for removal of epiretinal membrane with no additional complications