2,839 research outputs found

    Reasoned action approach to analyze differences in athletes\u27 physical activity during COVID-19

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    The purpose of this study was to examine the reasoned action approach (RAA) in relation to the impact of COVID-19 on college athletes’ physical activity (PA). Participants were college athletes (ages 18-22 years) who were involved in university, club, and/or intramural sport. The RAA constructs were measured for the three different types of PA behaviors. Statistical analyses included ANOVA and multiple regression analyses to evaluate the RAA determinants of PA intentions. Results partially supported theoretical expectations. All RAA constructs had an impact on perceived norms indicating a dominant influence. Remote social interaction/training during isolation periods are suggested to promote sustained conditioning among college athletes

    Evaluation of a village-informant driven demographic surveillance system in Karonga, Northern Malawi

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    This paper describes and evaluates the first demographic surveillance system (DSS) in Malawi, covering a rural population of 30,000. Unlike others, the Karonga DSS relies on trained village informants using formatted registers for the primary notification of vital events and migrations. Seven project enumerators subsequently collect detailed data on events notified by the village informants, using stringent identification procedures for households and individuals. Internal movements are traced systematically to augment event registration and data quality. Continuous evaluation of data collection is built into the methods. A re-census conducted after 2 years indicated that the routine system had registered 97% of 1,588 births, 99% of 521 deaths and 92% of 13,168 movements.demographic surveillance system, evaluation, INDEPTH network, Karonga, Malawi, methods, migration, village informant, vital registration

    Broadband circularly-polarized infrared emission from multilayer metamaterials

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    Development of a 2D metamaterial that preferentially emits broadband circularly-polarized (CP) infrared radiation is hindered by the fact that orthogonal electric-field components are uncorrelated at the surface of the thermal emitter, a consequence of the fluctuation-dissipation theorem. We achieve broadband CP thermal emission by fabricating a meanderline quarter-wave retarder on a transparent thermal-isolation layer. Behind this isolation layer, in thermal contact with the emitter, is a wire-grid polarizer. Along with an unavoidable linear polarized radiation characteristic from the meanderline, we measured a degree of circular polarization (DOCP) of 28%, averaged over the 8- to 12 mu m band

    Brief of Law Professors as \u3cem\u3eAmici Curiae\u3c/em\u3e in Support of Petitioner

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    Amici curiae respectfully submit this brief in support of Petitioner, Edward Lane, encouraging the reversal of the judgment of the Eleventh Circuit, because the judgment below is inconsistent with both the Court’s general historical approach to public employee speech and the specific approach to such speech that the Court adopted in Garcetti v. Ceballos, 547 U.S. 410 (2006). Amici are law professors who teach and write about the constitutional rights of public employees and have published a number of scholarly articles on these topics. Amici have no financial stake in the outcome of this case, and in this brief do not ask the Court to reconsider Garcetti. But we are troubled by the tendency in some courts of appeals to misread this Court’s decision in Garcettito articulate ever-broadening readings of the narrow exemption from First Amendment protection the Court carved out. We file this brief to urge this Court to correct these rulings by clarifying the narrow nature of the exemption it recognized

    Exploring Model Misspecification in Statistical Finite Elements via Shallow Water Equations

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    The abundance of observed data in recent years has increased the number of statistical augmentations to complex models across science and engineering. By augmentation we mean coherent statistical methods that incorporate measurements upon arrival and adjust the model accordingly. However, in this research area methodological developments tend to be central, with important assessments of model fidelity often taking second place. Recently, the statistical finite element method (statFEM) has been posited as a potential solution to the problem of model misspecification when the data are believed to be generated from an underlying partial differential equation system. Bayes nonlinear filtering permits data driven finite element discretised solutions that are updated to give a posterior distribution which quantifies the uncertainty over model solutions. The statFEM has shown great promise in systems subject to mild misspecification but its ability to handle scenarios of severe model misspecification has not yet been presented. In this paper we fill this gap, studying statFEM in the context of shallow water equations chosen for their oceanographic relevance. By deliberately misspecifying the governing equations, via linearisation, viscosity, and bathymetry, we systematically analyse misspecification through studying how the resultant approximate posterior distribution is affected, under additional regimes of decreasing spatiotemporal observational frequency. Results show that statFEM performs well with reasonable accuracy, as measured by theoretically sound proper scoring rules.Comment: 16 pages, 9 figures, 4 tables, submitted versio

    Canine Sense and Sensibility: Tipping Points and Response Latency Variability as an Optimism Index in a Canine Judgement Bias Assessment

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    Recent advances in animal welfare science used judgement bias, a type of cognitive bias, as a means to objectively measure an animal\u27s affective state. It is postulated that animals showing heightened expectation of positive outcomes may be categorised optimistic, while those showing heightened expectations of negative outcomes may be considered pessimistic. This study pioneers the use of a portable, automated apparatus to train and test the judgement bias of dogs. Dogs were trained in a discrimination task in which they learned to touch a target after a tone associated with a lactose-free milk reward and abstain from touching the target after a tone associated with water. Their judgement bias was then probed by presenting tones between those learned in the discrimination task and measuring their latency to respond by touching the target. A Cox\u27s Proportional Hazards model was used to analyse censored response latency data. Dog and Cue both had a highly significant effect on latency and risk of touching a target. This indicates that judgement bias both exists in dogs and differs between dogs. Test number also had a significant effect, indicating that dogs were less likely to touch the target over successive tests. Detailed examination of the response latencies revealed tipping points where average latency increased by 100% or more, giving an indication of where dogs began to treat ambiguous cues as predicting more negative outcomes than positive ones. Variability scores were calculated to provide an index of optimism using average latency and standard deviation at cues after the tipping point. The use of a mathematical approach to assessing judgement bias data in animal studies offers a more detailed interpretation than traditional statistical analyses. This study provides proof of concept for the use of an automated apparatus for measuring cognitive bias in dogs

    Comparison of Bystander Cardiopulmonary Resuscitation (BCPR) Performance in the Absence and Presence of Timing Devices for Coordinating Delivery of Ventilatory Breaths and Cardiac Compressions in a Model of Adult Cardiopulmonary Arrest

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    Astronaut crew medical officers (CMO) aboard the International Space Station (ISS) receive 40 hours of medical training during the 18 months preceding each mission. Part of this training ilncludes twoperson cardiopulmonary resuscitation (CPR) per training guidelines from the American Heart Association (AHA). Recent studies concluded that the use of metronomic tones improves the coordination of CPR by trained clinicians. Similar data for bystander or "trained lay people" (e.g. CMO) performance of CPR (BCPR) have been limited. The purpose of this study was to evailuate whether use of timing devices, such as audible metronomic tones, would improve BCPR perfomance by trained bystanders. Twenty pairs of bystanders trained in two-person BCPR performled BCPR for 4 minutes on a simulated cardiopulmonary arrest patient using three interventions: 1) BCPR with no timing devices, 2) BCPR plus metronomic tones for coordinating compression rate only, 3) BCPR with a timing device and metronome for coordinating ventilation and compression rates, respectively. Bystanders were evaluated on their ability to meet international and AHA CPR guidelines. Bystanders failed to provide the recommended number of breaths and number of compressions in the absence of a timing device and in the presence of audible metronomic tones for only coordinating compression rate. Bystanders using timing devices to coordinate both components of BCPR provided the reco number of breaths and were closer to providing the recommended number of compressions compared with the other interventions. Survey results indicated that bystanders preferred to use a metronome for delivery of compressions during BCPR. BCPR performance is improved by timing devices that coordinate both compressions and breaths

    Protecting patient privacy when sharing patient-level data from clinical trials

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    Abstract Background Greater transparency and, in particular, sharing of patient-level data for further scientific research is an increasingly important topic for the pharmaceutical industry and other organisations who sponsor and conduct clinical trials as well as generally in the interests of patients participating in studies. A concern remains, however, over how to appropriately prepare and share clinical trial data with third party researchers, whilst maintaining patient confidentiality. Clinical trial datasets contain very detailed information on each participant. Risk to patient privacy can be mitigated by data reduction techniques. However, retention of data utility is important in order to allow meaningful scientific research. In addition, for clinical trial data, an excessive application of such techniques may pose a public health risk if misleading results are produced. After considering existing guidance, this article makes recommendations with the aim of promoting an approach that balances data utility and privacy risk and is applicable across clinical trial data holders. Discussion Our key recommendations are as follows: 1. Data anonymisation/de-identification: Data holders are responsible for generating de-identified datasets which are intended to offer increased protection for patient privacy through masking or generalisation of direct and some indirect identifiers. 2. Controlled access to data, including use of a data sharing agreement: A legally binding data sharing agreement should be in place, including agreements not to download or further share data and not to attempt to seek to identify patients. Appropriate levels of security should be used for transferring data or providing access; one solution is use of a secure ‘locked box’ system which provides additional safeguards. Summary This article provides recommendations on best practices to de-identify/anonymise clinical trial data for sharing with third-party researchers, as well as controlled access to data and data sharing agreements. The recommendations are applicable to all clinical trial data holders. Further work will be needed to identify and evaluate competing possibilities as regulations, attitudes to risk and technologies evolve
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