Mid-Infrared Instrumentation for the European Extremely Large Telescope

MIDIR is the proposed thermal/mid-IR imager and spectrograph for the European Extremely Large Telescope (E-ELT). It will cover the wavelength range of 3 to at least 20 microns. Designed for diffraction-limited performance over the entire wavelength range, MIDIR will require an adaptive optics system; a cryogenically cooled system could offer optimal performance in the IR, and this is a critical aspect of the instrument design. We present here an overview of the project, including a discussion of MIDIR's science goals and a comparison with other infrared (IR) facilities planned in the next decade; top level requirements derived from these goals are outlined. We describe the optical and mechanical design work carried out in the context of a conceptual design study, and discuss some important issues to emerge from this work, related to the design, operation and calibration of the instrument. The impact of telescope optical design choices on the requirements for the MIDIR instrument is demonstrated.Comment: for publication in SPIE Proceedings vol. 6692, Cryogenic Optical Systems and Instrumentation XII, eds. J.B. Heaney and L.G. Burriesci, San Diego, Aug 200

Mid-Infrared Spectra of Classical AGN Observed with the Spitzer Space Telescope

Full low resolution (65<R<130) and high resolution (R~600) spectra between 5 microns and 37 microns obtained with the Infrared Spectrograph (IRS) on the Spitzer Space Telescope are presented for eight classical active galactic nuclei (AGN) which have been extensively studied previously. Spectra of these AGN are presented as comparison standards for the many objects, including sources at high redshift, which are being observed spectroscopically in the mid-infrared for the first time using the IRS. The AGN are NGC4151, Markarian 3, I Zwicky 1, NGC 1275, Centaurus A, NGC 7469, Markarian 231, and NGC 3079. These sources are used to demonstrate the range of infrared spectra encountered in objects which have widely different classification criteria at other wavelengths but which unquestionably contain AGN. Overall spectral characteristics - including continuum shape, nebular emission lines, silicate absorption and emission features, and PAH emission features - are considered to understand how spectral classifications based on mid-infrared spectra relate to those previously derived from optical spectra. The AGN are also compared to the same parameters for starburst galaxies such as NGC 7714 and the compact, low metallicity starburst SBS 0335-052 previously observed with the IRS. Results confirm the much lower strengths of PAH emission features in AGN, but there are no spectral parameters in this sample which unambiguously distinguish AGN and starbursts based only on the slopes of the continuous spectra.Comment: Accepted by Ap

First mid-infrared spectrum of a faint high-z galaxy: Observations of CFRS 14.1157 with the Infrared Spectrograph on the Spitzer Space Telescope

The unprecedented sensitivity of the Infrared Spectrograph on the Spitzer Space Telescope allows for the first time the measurement of mid-infrared spectra from 14 to 38 microns of faint high-z galaxies. This unique capability is demonstrated with observations of sources having 16 micron fluxes of 3.6 mJy (CFRS 14.1157) and 0.35 mJy (CFRS 14.9025). A spectral-fitting technique is illustrated which determines the redshift by fitting emission and absorption features characteristic of nearby galaxies to the spectrum of an unknown source. For CFRS 14.1157, the measured redshift is z = 1.00+/-0.20 in agreement with the published result of z = 1.15. The spectrum is dominated by emission from an AGN, similar to the nucleus of NGC 1068, rather than a typical starburst with strong PAH emission like M82. Such spectra will be crucial in characterizing the nature of newly discovered distant galaxies, which are too faint for optical follow-up.Comment: Accepted in ApJ Sup. Spitzer Special Issue, 4 pages, 5 figure

Isolation and characterization of feline dental pulp stem cells

Objectives The aim of this study was to isolate feline dental pulp stem cells (fDPSCs) and characterize their clonogenic and proliferative abilities, as well as their multipotency, immunophenotype and cytogenetic stability. Methods Dental pulp was isolated by explant culture from two cats &lt;1 year old at post mortem. Their clonogenicity was characterized using a colony-forming unit fibroblast assay, and their proliferative ability was quantified with a doubling time assay in passages 2, 4 and 6 (P2, P4 and P6, respectively). Multipotency was characterized with an in vitro trilineage differentiation assay in P2, and cells were immunophenotyped in P4 by flow cytometry. Chromosomic stability was evaluated by cytogenetic analysis in P2, P4 and P6. Results The fDPSCs displayed spindle and epithelial-like morphologies. Isolated cells showed a marked clonogenic capacity and doubling time was maintained from P2 to P6. Trilineage differentiation was obtained in one sample, while the other showed osteogenic and chondrogenic differentiation. Immunophenotypic analysis showed fDPSCs were CD45−, CD90+ and CD44+. Structural and numerical cytogenetic aberrations were observed in P2–P4. Conclusions and relevance In this study, fDPSCs from two cats were isolated by explant culture and immunophenotyped. Cells displayed clonogenic and proliferative ability, and multipotency in vitro, and signs of chromosomic instability were observed. Although a larger study is needed to confirm these results, this is the first report of fDPSC isolation and in vitro characterization

Spectroscopic Redshifts to z > 2 for Optically Obscured Sources Discovered with the Spitzer Space Telescope

We have surveyed a field covering 9.0 degrees^2 within the NOAO Deep Wide-Field Survey region in Bootes with the Multiband Imaging Photometer on the Spitzer Space Telescope (SST) to a limiting 24 um flux density of 0.3 mJy. Thirty one sources from this survey with F(24um) > 0.75 mJy which are optically very faint (R > 24.5 mag) have been observed with the low-resolution modules of the Infrared Spectrograph on SST. Redshifts derived primarily from strong silicate absorption features are reported here for 17 of these sources; 10 of these are optically invisible (R > 26 mag), with no counterpart in B_W, R, or I. The observed redshifts for 16 sources are 1.7 < z < 2.8. These represent a newly discovered population of highly obscured sources at high redshift with extreme infrared to optical ratios. Using IRS spectra of local galaxies as templates, we find that a majority of the sources have mid-infrared spectral shapes most similar to ultraluminous infrared galaxies powered primarily by AGN. Assuming the same templates also apply at longer wavelengths, bolometric luminosities exceed 10^13 L(solar).Comment: Accepted for publication on 7 Feb 2005 in ApJL. 7 pages 2 figure

Evelopment of the model of diagnosis of the risk of bankruptcy

The article presents an overview of foreign and domestic models for the diagnosis of bankruptcy risk, and gives a brief description of them. Also considered the development of our own model of bankruptcy risk diagnostics for Russian enterprise

Cryogenic setup for trapped ion quantum computing

We report on the design of a cryogenic setup for trapped ion quantum computing containing a segmented surface electrode trap. The heat shield of our cryostat is designed to attenuate alternating magnetic field noise, resulting in 120~dB reduction of 50~Hz noise along the magnetic field axis. We combine this efficient magnetic shielding with high optical access required for single ion addressing as well as for efficient state detection by placing two lenses each with numerical aperture 0.23 inside the inner heat shield. The cryostat design incorporates vibration isolation to avoid decoherence of optical qubits due to the motion of the cryostat. We measure vibrations of the cryostat of less than $\pm$20~nm over 2~s. In addition to the cryogenic apparatus, we describe the setup required for an operation with $^{\mathrm{40}}$Ca$^{\mathrm{+}}$ and $^{\mathrm{88}}$Sr$^{\mathrm{+}}$ ions. The instability of the laser manipulating the optical qubits in $^{\mathrm{40}}$Ca$^{\mathrm{+}}$ is characterized yielding a minimum of its Allan deviation of 2.4$\cdot$10$^{\mathrm{-15}}$ at 0.33~s. To evaluate the performance of the apparatus, we trapped $^{\mathrm{40}}$Ca$^{\mathrm{+}}$ ions, obtaining a heating rate of 2.14(16)~phonons/s and a Gaussian decay of the Ramsey contrast with a 1/e-time of 18.2(8)~ms

Spitzer-IRS Spectroscopy of the Prototypical Starburst Galaxy NGC7714

We present observations of the starburst galaxy NGC 7714 with the Infrared Spectrograph IRS on board the Spitzer Space Telescope. The spectra yield a wealth of ionic and molecular features that allow a detailed characterization of its properties. NGC 7714 has an HII region-like spectrum with strong PAH emission features. We find no evidence for an obscured active galactic nucleus, and with [NeIII]/[NeII]~0.73, NGC7714 lies near the upper end of normal-metallicity starburst galaxies. With very little slicate absorption and a temperature of the hottest dust component of 340K, NGC 7714 is the perfect template for a young, unobscured starburstComment: To appear in the special ApJSS issue on early results from Spitze

PAH Emission from Ultraluminous Infrared Galaxies

We explore the relationships between the Polycyclic Aromatic Hydrocarbon (PAH) feature strengths, mid-infrared continuum luminosities, far-infrared spectral slopes, optical spectroscopic classifications, and silicate optical depths within a sample of 107 ULIRGs observed with the Infrared Spectrograph on the Spitzer Space Telescope. The detected 6.2 micron PAH equivalent widths (EQWs) in the sample span more than two orders of magnitude (0.006-0.8 micron), and ULIRGs with HII-like optical spectra or steep far-infrared spectral slopes (S_{25} / S_{60} < 0.2) typically have 6.2 micron PAH EQWs that are half that of lower-luminosity starbursts. A significant fraction (~40-60%) of HII-like, LINER-like, and cold ULIRGs have very weak PAH EQWs. Many of these ULIRGs also have large (tau_{9.7} > 2.3) silicate optical depths. The far-infrared spectral slope is strongly correlated with PAH EQW, but not with silicate optical depth. In addition, the PAH EQW decreases with increasing rest-frame 24 micron luminosity. We argue that this trend results primarily from dilution of the PAH EQW by continuum emission from dust heated by a compact central source, probably an AGN. High luminosity, high-redshift sources studied with Spitzer appear to have a much larger range in PAH EQW than seen in local ULIRGs, which is consistent with extremely luminous starburst systems being absent at low redshift, but present at early epochs.Comment: 15 pages, 9 Figures; Accepted for publication in Ap

Are men who have sex with men in Europe protected from hepatitis B?

Hepatitis B vaccination is recommended for men who have sex with men (MSM) in many countries, but information on vaccine coverage is scarce. We studied hepatitis B vaccination programmes and coverage among MSM in Europe to guide prevention. From a large (N = 174 209) pan-European MSM survey (EMIS-2010), we used data on self-reported hepatitis B vaccination, age, education, settlement size and disclosure of the same-sex sexual orientation ('outness'). We excluded participants with a history of hepatitis B. In multilevel (participants, countries) logistic regression models, we calculated adjusted odds ratios (aOR) with 95% confidence intervals (95% CI). We analysed data of 163 987 MSM in 38 European countries: 38.3% were 'out' to all or almost all, 56.4% reported vaccination against hepatitis B and 65.5% lived in countries with free recommended hepatitis B vaccination for MSM. In the final model the odds for being vaccinated increased with outness ('out to all or almost all': aOR 1.76, 95% CI 1.70-1.83 vs. 'out to no one') and with living in countries, where hepatitis B vaccination was recommended and free-of-charge for MSM (aOR 2.21, 95% CI 1.47-3.32 vs. 'no or unclear recommendation'). To increase hepatitis B vaccination coverage among MSM, implementation of MSM-specific recommendations and improvement of the societal climate for MSM is needed