41 research outputs found
Simplified Quantum Process Tomography
We propose and evaluate experimentally an approach to quantum process
tomography that completely removes the scaling problem plaguing the standard
approach. The key to this simplification is the incorporation of prior
knowledge of the class of physical interactions involved in generating the
dynamics, which reduces the problem to one of parameter estimation. This allows
part of the problem to be tackled using efficient convex methods, which, when
coupled with a constraint on some parameters allows globally optimal estimates
for the Kraus operators to be determined from experimental data. Parameterising
the maps provides further advantages: it allows the incorporation of mixed
states of the environment as well as some initial correlation between the
system and environment, both of which are common physical situations following
excitation of the system away from thermal equilibrium. Although the approach
is not universal, in cases where it is valid it returns a complete set of
positive maps for the dynamical evolution of a quantum system at all times.Comment: Added references to interesting related work by Bendersky et a
Use of tetravalent galabiose for inhibition of Streptococcus suis serotype 2 infection in a mouse model
Peer reviewe
Encoding a qubit into multilevel subspaces
We present a formalism for encoding the logical basis of a qubit into
subspaces of multiple physical levels. The need for this multilevel encoding
arises naturally in situations where the speed of quantum operations exceeds
the limits imposed by the addressability of individual energy levels of the
qubit physical system. A basic feature of the multilevel encoding formalism is
the logical equivalence of different physical states and correspondingly, of
different physical transformations. This logical equivalence is a source of a
significant flexibility in designing logical operations, while the multilevel
structure inherently accommodates fast and intense broadband controls thereby
facilitating faster quantum operations. Another important practical advantage
of multilevel encoding is the ability to maintain full quantum-computational
fidelity in the presence of mixing and decoherence within encoding subspaces.
The formalism is developed in detail for single-qubit operations and
generalized for multiple qubits. As an illustrative example, we perform a
simulation of closed-loop optimal control of single-qubit operations for a
model multilevel system, and subsequently apply these operations at finite
temperatures to investigate the effect of decoherence on operational fidelity.Comment: IOPart LaTeX, 2 figures, 31 pages; addition of a numerical simulatio
Entanglement quantification from incomplete measurements: Applications using photon-number-resolving weak homodyne detectors
The certificate of success for a number of important quantum information
processing protocols, such as entanglement distillation, is based on the
difference in the entanglement content of the quantum states before and after
the protocol. In such cases, effective bounds need to be placed on the
entanglement of non-local states consistent with statistics obtained from local
measurements. In this work, we study numerically the ability of a novel type of
homodyne detector which combines phase sensitivity and photon-number resolution
to set accurate bounds on the entanglement content of two-mode quadrature
squeezed states without the need for full state tomography. We show that it is
possible to set tight lower bounds on the entanglement of a family of two-mode
degaussified states using only a few measurements. This presents a significant
improvement over the resource requirements for the experimental demonstration
of continuous-variable entanglement distillation, which traditionally relies on
full quantum state tomography.Comment: 18 pages, 6 figure
Quantum Process Tomography of a Universal Entangling Gate Implemented with Josephson Phase Qubits
Quantum logic gates must perform properly when operating on their standard
input basis states, as well as when operating on complex superpositions of
these states. Experiments using superconducting qubits have validated the truth
table for particular implementations of e.g. the controlled-NOT gate [1,2], but
have not fully characterized gate operation for arbitrary superpositions of
input states. Here we demonstrate the use of quantum process tomography (QPT)
[3,4] to fully characterize the performance of a universal entangling gate
between two superconducting quantum bits. Process tomography permits complete
gate analysis, but requires precise preparation of arbitrary input states,
control over the subsequent qubit interaction, and simultaneous single-shot
measurement of the output states. We use QPT to measure the fidelity of the
entangling gate and to quantify the decoherence mechanisms affecting the gate
performance. In addition to demonstrating a promising fidelity, our entangling
gate has a on/off ratio of 300, a level of adjustable coupling that will become
a requirement for future high-fidelity devices. This is the first solid-state
demonstration of QPT in a two-qubit system, as solid-state process tomography
has previously only been demonstrated with single qubits [5,6]
The Short-Term Effect of Weight Loss Surgery on Volumetric Breast Density and Fibroglandular Volume
Purpose:
Obesity and breast density are both associated with an increased risk of breast cancer and are potentially modifiable. Weight loss surgery (WLS) causes a significant reduction in the amount of body fat and a decrease in breast cancer risk. The effect of WLS on breast density and its components has not been documented. Here, we analyze the impact of WLS on volumetric breast density (VBD) and on each of its components (fibroglandular volume and breast volume) by using three-dimensional methods.
Materials and Methods:
Fibroglandular volume, breast volume, and their ratio, the VBD, were calculated from mammograms before and after WLS by using Volparaâ„¢ automated software.
Results:
For the 80 women included, average body mass index decreased from 46.0 ± 7.22 to 33.7 ± 7.06 kg/m2. Mammograms were performed on average 11.6 ± 9.4 months before and 10.1 ± 7 months after WLS. There was a significant reduction in average breast volume (39.4 % decrease) and average fibroglandular volume (15.5 % decrease), and thus, the average VBD increased from 5.15 to 7.87 % (p < 1 × 10−9) after WLS. When stratified by menopausal status and diabetic status, VBD increased significantly in all groups but only perimenopausal and postmenopausal women and non-diabetics experienced a significant reduction in fibroglandular volume.
Conclusions:
Breast volume and fibroglandular volume decreased, and VBD increased following WLS, with the most significant change observed in postmenopausal women and non-diabetics. Further studies are warranted to determine how physical and biological alterations in breast density components after WLS may impact breast cancer risk.ECU Open Access Publishing Support Fun
Bridging particle and wave sensitivity in a configurable detector of positive operator-valued measures.
We report an optical detector with tunable positive operator-valued measures. The device is based on a combination of weak-field homodyne techniques and photon-number-resolving detection. The resulting positive operator-valued measures can be continuously tuned from Fock-state projectors to a variety of phase-dependent quantum-state measurements by adjusting different system parameters such as local oscillator coupling, amplitude, and phase, allowing thus not only detection but also preparation of exotic quantum states. Experimental tomographic reconstructions of classical benchmark states are presented as a demonstration of the detector capabilities
Synthesis of multivalent Streptococcus suis adhesion inhibitors by enzymatic cleavage of polygalacturonic acid and 'click' conjugation
A galabiose disaccharide building block was synthesized by an efficient pectinase cleavage of polygalacturonic acid and subsequent chemical functional group transformations. Besides the disaccharide, the corresponding trisaccharide was also obtained and modified. The compounds were subsequently conjugated to dendrimers with up to eight end groups using 'click' chemistry. The compounds were evaluated as inhibitors of adhesion of the pathogen Streptococcus suis in a hemagglutination assay and strong inhibition was observed for the tetra- and octavalent galabiose compound with MIC values in the low nanomolar range. The corresponding octavalent trisaccharide was a ca. 20-fold weaker inhibitor