Evaluation of the erosive capacity of children?s beverages on primary teeth enamel : an in vitro study

The consumption of acidified beverages, associated with lower mineralization of primary enamel, is the ideal combination for the development and progression of dental erosion. The objective of this study is to analyze the erosive capacity and the surface roughness of primary teeth enamel after exposure to three different brands of grape juices. Forty enamel blocks of primary teeth were obtained, attened and polished. They were submitted to initial surface roughness analysis (baseline), and randomly assigned into four groups (n = 10): NAT: natural grape juice (Campo Largo); IND: industrialized grape juice (Dell Vale Kapo); SOY: soy-based grape juice (Ades); and CONT (control): artificial saliva. Blocks were immersed for 2 min, 3 times per day, for 9 days. During the whole time of the experiment, the enamel blocks were stored in artificial saliva. After the 9 days, the roughness parameters were determined again. The beverages were analyzed for pH and titratable acidity. Data were statistically analyzed (? = 0.05). The surface roughness did not differ significantly among groups (p > 0.05). However, after the immersion in the different grape juices, the surface roughness values increased significantly (p< 0.05). The pH values were weakly correlated to acidity values; NAT showed the highest titratable acidity values than the other juices (p<0.05). Although the surface roughness values of the experimental groups did not differ from the control group, there was a difference in initial and final roughness in all groups. Grape juices, especially natural, may have an erosive capacity, changing the surface roughness of primary dental enamel

COMPARATIVE ANALYSIS OF THE EFFECTS OF MELOXICAM AND FLUNIXIN MEGLUMINE ON RENAL FUNCTION OF WISTAR RATS

O presente trabalho avaliou a função renal de ratos Wistar submetidos ao tratamento com meloxicam (ME) e flunixin meglumine (FM). Foram utilizados 66 ratos Wistar distribuídos em três grupos (n=22). O grupo controle recebeu solução fisiológica, enquanto os grupos tratados com ME e FM receberam duas doses de 2 e 1,1 mg/Kg, respectivamente, da medicação por via subcutânea. Todos os animais foram submetidos à coleta de 2 mL de sangue no início e ao fim do estudo para posterior detecção dos níveis de ureia. A partir destes dados foi feita a aplicação do teste ANOVA-fator duplo. O nível de significância utilizado foi ≤0,05. Foi possível concluir que o uso de ambos os medicamentos nas dosagens terapêuticas provocaram alterações na função renal dos animais indicando que o uso destes medicamentos deve ser feito com cautela quando utilizados em roedores

Oral rehabilitation with removable dental prosthesis in a six-year-old patient with hypohidrotic ectodermal dysplasia

Introduction: Ectodermal dysplasia is an abnormality of the ectoderm and its derivatives, phenotypically expressed in males and genetically inherited from mothers. Objective: To report the efficacy of the prosthetics treatment of severe ectodermal dysplasia in a 6-year-old boy with hypohidrotic ectodermal dysplasia (HED). Case report: The boy had difficulty in speaking and eating and the condition also affected his self-esteem. Prosthetic treatments included the construction of acrylic custom trays, determination of the vertical dimension of occlusion (VDO), construction of upper and lower dentures, and palatal expansion procedure. Conclusion: Significant improvements in the patient’s stomatognathic functionand self-esteem were evident.Introduction: Ectodermal dysplasia is an abnormality of the ectoderm and its derivatives, phenotypically expressed in males and genetically inherited from mothers. Objective: To report the efficacy of the prosthetics treatment of severe ectodermal dysplasia in a 6-year-old boy with hypohidrotic ectodermal dysplasia (HED). Case report: The boy had difficulty in speaking and eating and the condition also affected his self-esteem. Prosthetic treatments included the construction of acrylic custom trays, determination of the vertical dimension of occlusion (VDO), construction of upper and lower dentures, and palatal expansion procedure. Conclusion: Significant improvements in the patient’s stomatognathic functionand self-esteem were evident

Free gingival graft to increase gingival dimensions in Down syndrome patients: clinical case report

Introduction: Down Syndrome (DS) patients have increased susceptibility to the development of periodontal diseases by the occurrence of several factors, such as inadequate hygiene, mouth breathing, dental morphology, leukocyte reduction and increased inflammatory mediators. Objective: This study aimed to review the literature on the main aspects of DS and present a clinical case of a DS patient treated with basic periodontal therapy and free gingival graft surgery. Case report: DS patient, leucoderma, aged 26 years showed gingival recession and little amount of keratinized tissue in the area of teeth #31 and #41. After surgery, there was an increase in the keratinized tissue band. Conclusion: The free gingival graft surgery performed in DS patients was effective, as the increase of keratinized tissue band occurred

Facial anthropometry in an adult male with Sotos syndrome

Introduction: Sotos Syndrome is a dominant autossomic disease caused by a mutation in NSD1 gene localized in chromosome 5. The craniofacial phenotype of Sotos Syndrome is quite distinctive, especially in the young child, and includes macrocephaly, widelyspaced eyes, prominent chin and mandible, high and curved forehead, palpebral slits oblique and downward, long and narrowface. This phenotype plays an important role in the identification of this syndrome. Objective: The aim of this study was to analyze the craniofacial anthropometric landmarks of a young adult male with medical diagnosis of Sotos Syndrome. Material and methods: Using noninvasive method of craniofacial anthropometry, twenty five anthropometric measurements were taken of the individual and compared with the facial pattern of non-syndromic individuals,matched in gender and age. The findings were standards and converted to Z-scores. Results: the data analysis showed that the majority of variables were in supernormal range (greater than +2 standard deviation (SD). None none of them was in the subnormal range (less than –2SD). Conclusion: Anthropometric analysis of Sotos Syndrome demonstrated the usefulness of craniofacial analysisin defining abnormal craniofacial dimensions.Introduction: Sotos Syndrome is a dominant autossomic disease caused by a mutation in NSD1 gene localized in chromosome 5. The craniofacial phenotype of Sotos Syndrome is quite distinctive, especially in the young child, and includes macrocephaly, widelyspaced eyes, prominent chin and mandible, high and curved forehead, palpebral slits oblique and downward, long and narrowface. This phenotype plays an important role in the identification of this syndrome. Objective: The aim of this study was to analyze the craniofacial anthropometric landmarks of a young adult male with medical diagnosis of Sotos Syndrome. Material and methods: Using noninvasive method of craniofacial anthropometry, twenty five anthropometric measurements were taken of the individual and compared with the facial pattern of non-syndromic individuals,matched in gender and age. The findings were standards and converted to Z-scores. Results: the data analysis showed that the majority of variables were in supernormal range (greater than +2 standard deviation (SD). None none of them was in the subnormal range (less than –2SD). Conclusion: Anthropometric analysis of Sotos Syndrome demonstrated the usefulness of craniofacial analysisin defining abnormal craniofacial dimensions

EVALUATION OF CANINE ROOT CANAL THERAPY USING PROTAPER® SYSTEM

Industry data for pet products has revealed that most Brazilian families have pets in their homes and that that humans give a large amount of attention to their pets. Oral diseases are among the most quickly perceived and treated of pet pathologies; and the most common of these is periodontal disease, which can affect the pulp and requires endodontic treatment. Recently, the evelopment of superelastic nickel-titanium alloys has revolutionized endodontic therapy, as the alloys have been used to develop novel rotary instruments. The goal of this study was to evaluate the efficiency of such rotary instruments in the ex vivo shaping of canine dental root canal therapy. The sample consisted of 40 canine incisors that had been extracted due to periodontal disease. The endodontic access procedure was performed, and the root canal was prepared using ProTaper® rotary instruments. Before and after shaping the canals, teeth were examined radiographically. The cervical, middle, and apical thirds were analyzed using the Image Lab® program. Results showed that the ProTaper® rotary instruments removed significant amounts of dentine (cervical third: T=-13.225, p<0.0001; middle third: W=410, p<0.000 1; apical third: W=410, p<0.0001). Regarding shaping of the canal, the apical third had expanded significantly, and there was a positive correlation between measurements in all analyzed thirds (cervical third: r=0.924; middle third: r=0.980; apical third: r=0.993.) This demonstrates an increase in the surface area of the channels in all three thirds. In this study, we conclude that the rotary instruments used were efficient in shaping root canals.Keywords: Endodontics, rotary instruments, root cana

Analysis of Polymorphisms in the Lactotransferrin Gene Promoter and Dental Caries

Regarding host aspects, there has been strong evidence for a genetic component in the etiology of caries. The salivary protein lactotransferrin (LTF) exhibits antibacterial activity, but there is no study investigating the association of polymorphisms in the promoter region of LTF gene with caries. The objective of this study was firstly to search the promoter region of the human LTF gene for variations and, if existent, to investigate the association of the identified polymorphisms with dental caries in 12-year-old students. From 687 unrelated, 12-year-old, both sex students, 50 individuals were selected and divided into two groups of extreme phenotypes according to caries experience: 25 students without (DMFT = 0) and 25 with caries experience (DMFT ≥ 4). The selection of individuals with extreme phenotypes augments the chances to find gene variations which could be associated with such phenotypes. LTF gene-putative promoter region (+39 to −1143) of the selected 50 individuals was analyzed by high-resolution melting technique. Fifteen students, 8 without (DMFT = 0) and 7 with caries experience (mean DMFT = 6.28), presented deviations of the pattern curve suggestive of gene variations and were sequenced. However, no polymorphisms were identified in the putative promoter region of the LTF gene

Evaluation of anthropometric facial landmarks in woman with Blepharophimosis, Ptosis, and Epicanthus Inversus Syndrome (BPES)

Introduction: Blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES) is a syndrome easily recognized by facial appearance. In this sense, the facial anthropometry is a simple and non-invasive way to evaluate the morphology of the facial surface of individuals, thus, defining the craniofacial dimensions. Objective: To evaluate the facial anthropometric measurements of a Caucasian female, aged 20 years, diagnosed with BPES and to compare these measures with the values described in the literature for non-syndromic woman.Material and methods: This research is an observational study of a Caucasian female, aged 20 years, who was diagnosed with BPES. Frontal photographs were taken, and the images analyzed by nine researchers calibrated in Image J® software. The facial measurements evaluated were head, face, orbits, nose, and labio-oral region and were compared with non-syndromic woman. Results: All vertical and horizontal face measurements were higher than that of otherfemales from Caucasian groups. BPES woman also presented bilateral ptosis and the main differences appear in the region of the orbits. Conclusion: The anthropometric facial analysis of BPES woman showed a significant change in the facial landmarks.Introduction: Blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES) is a syndrome easily recognized by facial appearance. In this sense, the facial anthropometry is a simple and non-invasive way to evaluate the morphology of the facial surface of individuals, thus, defining the craniofacial dimensions. Objective: To evaluate the facial anthropometric measurements of a Caucasian female, aged 20 years, diagnosed with BPES and to compare these measures with the values described in the literature for non-syndromic woman.Material and methods: This research is an observational study of a Caucasian female, aged 20 years, who was diagnosed with BPES. Frontal photographs were taken, and the images analyzed by nine researchers calibrated in Image J® software. The facial measurements evaluated were head, face, orbits, nose, and labio-oral region and were compared with non-syndromic woman. Results: All vertical and horizontal face measurements were higher than that of otherfemales from Caucasian groups. BPES woman also presented bilateral ptosis and the main differences appear in the region of the orbits. Conclusion: The anthropometric facial analysis of BPES woman showed a significant change in the facial landmarks

Single Nucleotides Polymorphisms in COX2 Gene and their Association with Signs and Symptoms of Teething – A Pilot Study

Objective: To investigate the association between single nucleotide polymorphisms in the COX2 gene (rs689466 and rs5275) and local and systemic signs and symptoms of teething. Material and Methods: Forty-four pairs of mothers-babies/toddlers were included. Erupted primary teeth were evaluated during clinical examination. Local and systemic signs and symptoms of teething were obtained from mothers\u27 reporting via anamnesis. Samples of buccal cells were retrieved for DNA genotyping using real-time PCR. The T-test, Chi-square test, logistic regression, and haplotype analyses were applied. Results: Almost all mothers (95.5%) reported at least one local or systemic sign and symptom of teething. The most common was increased salivation (79.5%), diarrhea (72.3%), and fever (70.5%). The mean number of signs and symptoms per child was higher in boys than girls (mean = 5.1; SD= 1.5; p=0.008). Sleep disturbance (p=0.03) and loss of appetite (p=0.05) were more reported in boys. The rs689466 and rs5275 were not associated with signs and symptoms of teething (p&gt;0.05). Conclusion: The single nucleotide polymorphisms in the COX2 gene (rs689466 and rs5275) were not associated with local and systemic signs and symptoms of teething

Tratamento de pigmentações melânicas com instrumentos rotatórios e lâmina de bisturi Treatment of melanic pigmentations with rotary instruments and scalpel blade

Introduction: Oral pigmentary lesions may have different clinical characteristics, ranging from physiological pigmentation, such as melanin spots, to something more serious, such as malignant melanoma. Due to the great variety of pigmented lesions, the treatments are varied and individualized. Objective: This clinical case reports a case of melanocytic removal through a surgical technique that associates rotary instruments and scalpel blade. Case report: A 45-year-old patient, melanoderma, sought care at the Positivo University, complaining about the dark spots visible on his gum, and the discomfort they caused him when smiling. After the clinical examination, the presence of melanocytic pigmentation was diagnosed and the proposed treatment was surgical removal of spots with a drill and scalpel blade. In the immediate postoperative period, the patient presented good healing and reported only mild burning in the first three days. After 60 days, the gingiva was healed, with no relapsing spots. Conclusion: The technique chosen was effective because it presented adequate healing and absence of relapse of the pigmentation in the postoperative follow-upIntroduction: Oral pigmentary lesions may have different clinical characteristics, ranging from physiological pigmentation, such as melanin spots, to something more serious, such as malignant melanoma. Due to the great variety of pigmented lesions, the treatments are varied and individualized. Objective: This clinical case reports a case of melanocytic removal through a surgical technique that associates rotary instruments and scalpel blade. Case report: A 45-year-old patient, melanoderma, sought care at the Positivo University, complaining about the dark spots visible on his gum, and the discomfort they caused him when smiling. After the clinical examination, the presence of melanocytic pigmentation was diagnosed and the proposed treatment was surgical removal of spots with a drill and scalpel blade. In the immediate postoperative period, the patient presented good healing and reported only mild burning in the first three days. After 60 days, the gingiva was healed, with no relapsing spots. Conclusion: The technique chosen was effective because it presented adequate healing and absence of relapse of the pigmentation in the postoperative follow-u