588 research outputs found
Advantage of four-electrode over two-electrode defibrillators
Defibrillation is the standard clinical treatment used to stop ventricular fibrillation. An electrical device delivers a controlled amount of electrical energy via a pair of electrodes in order to reestablish the normal heart rate. We propose a new technique that is a combination of biphasic shocks applied with a four-electrode system rather than the standard two-electrode system. We use a numerical model of a one-dimensional ring of cardiac tissue in order to test and evaluate the benefit of such a new technique. We compare three different shock protocols, namely, a monophasic and two types of biphasic shocks. The results obtained by using a four-electrode system are compared quantitatively with those obtained with the standard two-electrode system. We find that a huge reduction in defibrillation threshold is achieved with the four-electrode system. For the most efficient protocol (asymmetric biphasic), we obtain a reduction in excess of 80 % in the energy required for a defibrillation success rate of 90 %. The mechanisms of successful defibrillation are also analyzed. This reveals that the advantage of asymmetric biphasic shocks with four electrodes lies in the duration of the cathodal and anodal phase of the shock
Detecting unstable periodic spatio-temporal states of spatial extended chaotic systems
The method of detection of the unstable periodic spatio-temporal states of
spatial extended chaotic systems has been proposed. The application of this
method is illustrated by the consideration of two different systems: i) the
fluid model of Pierce diode being one of the fundamental system of the physics
of plasmas and microwave electronics and ii) the complex one-dimensional
Ginzburg-Landau equation demonstrating different regimes of spatio-temporal
chaos.Comment: 6 pages, 7 figure
Genetic characterization of Pepino mosaic virus isolates from Belgian greenhouse tomatoes reveals genetic recombination
Over a period of a few years, Pepino mosaic virus (PepMV) has become one of the most important viral diseases in tomato production worldwide. Infection by PepMV can cause a broad range of symptoms on tomato plants, often leading to significant financial losses. At present, five PepMV genotypes (EU, LP, CH2, US1 and US2) have been described, three of which (EU, LP and US2) have been reported in Europe. Thus far, no correlation has been found between different PepMV genotypes and the symptoms expressed in infected plants. In this paper, the genetic diversity of the PepMV population in Belgian greenhouses is studied and related to symptom development in tomato crops. A novel assay based on restriction fragment length polymorphism (RFLP) was developed to discriminate between the different PepMV genotypes. Both RFLP and sequence analysis revealed the occurrence of two genotypes, the EU genotype and the CH2 genotype, within tomato production in Belgium. Whereas no differences were observed in symptom expression between plants infected by one of the two genotypes, co-infection with both genotypes resulted in more severe PepMV symptoms. Furthermore, our study revealed that PepMV recombinants frequently occur in mixed infections under natural conditions. This may possibly result in the generation of viral variants with increased aggressivenes
Chaotic synchronization of coupled electron-wave systems with backward waves
The chaotic synchronization of two electron-wave media with interacting
backward waves and cubic phase nonlinearity is investigated in the paper. To
detect the chaotic synchronization regime we use a new approach, the so-called
time scale synchronization [Chaos, 14 (3) 603-610 (2004)]. This approach is
based on the consideration of the infinite set of chaotic signals' phases
introduced by means of continuous wavelet transform. The complex space-time
dynamics of the active media and mechanisms of the time scale synchronization
appearance are considered.Comment: 11 pages, 7 figures, published in CHAOS, 15 (2005) 01370
Planform selection in two-layer Benard-Marangoni convection
Benard-Marangoni convection in a system of two superimposed liquids is
investigated theoretically. Extending previous studies the complete
hydrodynamics of both layers is treated and buoyancy is consistently taken into
account. The planform selection problem between rolls, squares and hexagons is
investigated by explicitly calculating the coefficients of an appropriate
amplitude equation from the parameters of the fluids. The results are compared
with recent experiments on two-layer systems in which squares at onset have
been reported.Comment: 17 pages, 7 figures, oscillatory instability included, typos
corrected, references adde
Towards a quantitative phase-field model of two-phase solidification
We construct a diffuse-interface model of two-phase solidification that
quantitatively reproduces the classic free boundary problem on solid-liquid
interfaces in the thin-interface limit. Convergence tests and comparisons with
boundary integral simulations of eutectic growth show good accuracy for
steady-state lamellae, but the results for limit cycles depend on the interface
thickness through the trijunction behavior. This raises the fundamental issue
of diffuse multiple-junction dynamics.Comment: 4 pages, 2 figures. Better final discussion. 1 reference adde
Continuous intraocular pressure monitoring in patients with obstructive sleep apnea syndrome using a contact lens sensor
Purpose To analyse nocturnal intraocular pressure (IOP) fluctuations in patients with obstructive sleep apnea syndrome (OSAS) using a contact lens sensor (CLS) and to identify associations between the OSAS parameters determined by polysomnographic study (PSG) and IOP changes. Method Prospective, observational study. Twenty participants suspected of having OSAS were recruited. During PSG study, IOP was monitored using a CLS placed in the eye of the patient. The patients were classified according to the apnea-hypopnea index (AHI) in two categories, severe (>30) or mild/moderate (<30) OSAS. We evaluated several parameters determined by the IOP curves, including nocturnal elevations (acrophase) and plateau times in acrophase (PTs) defined by mathematical and visual methods. Results The IOP curves exhibited a nocturnal acrophase followed by PTs of varying extents at which the IOP remained higher than daytime measurement with small variations. We found significant differences in the length of the PTs in patients with severe OSAS compared to those with mild/moderate disease (P = 0.032/P = 0.028). We found a positive correlation between PTs and OSAS severity measured by the total number of apneic events (r = 0.681/ 0.751 P = 0.004/0.001) and AHI (r = 0.674/0.710, P = 0.004/0.002). Respiratory-related arousal and oxygen saturation also were associated significantly with the IOP PT length. Conclusions Periods of nocturnal IOP elevation lasted longer in severe OSAS patients than those with mild/moderate OSAS and correlate with the severity of the disease. The length of the nocturnal PT is also associated to respiratory parameters altered in patients with OSAS
Is it possible to improve the breaking bad news skills of residents when a relative is present? A randomised study.
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