Music and Physical Activity for Children with Impaired Communication in Preschoolers

Diplomová práce se zabývala významem hudebně pohybových aktivit u dětí s narušenou komunikační schopností v předškolním věku. Jejím cílem bylo zjistit, jaký vliv mají hudebně pohybové aktivity na osobnost těchto dětí. Práci tvořily dvě stěžejní oblasti. Jednalo se o část teoretickou, která objasňovala základní pojmosloví z oblasti narušené komunikační schopnosti a z oblasti hudby a hudebně pohybových činností. Empirická část zjišťovala, zda hudebně pohybové aktivity pozitivně ovlivňují narušenou komunikační schopnost dětí předškolního věku. Výsledky ukázaly, že vlivem hudebně pohybových aktivit postupně dochází ke zlepšení komunikačních schopností dětí, jejichž komunikační schopnost je narušena. Testováním bylo dále zjištěno, že děti s narušenou komunikační schopností mají deficity v oblasti rytmického cítění. Tato zjištění vyústila v navrhovaná opatření týkající se hudebně pohybových činností a terapie narušené komunikační schopnosti.This dissertation deals with importance of musical kinetic activities for preschool children with disrupted communication skills. Its aim is to detect the effects of musical kinetic activities on personalities of these children. The dissertation consists of two main parts - a theoretical part and an empirical part. The theoretical part clarifies basic terms from the sphere of disrupted communication skills and from the sphere of music and musical kinetic activities. The empirical part tries to find out whether the musical kinetic activities positively affect disrupted communication skills of preschool children. The results indicates that musical kinetic activities improve disrupted communication skills of preschool children gradually. Testing has proved that children with disrupted communication skills have difficulties with rhythmical feeling. These findings have resulted in suggested arrangements regarding musical kinetic activities and disrupted communication skills treatmen

The graduates research of the Department of Social Work FF UK

Souhrn diplomové práce Název práce: Výzkum absolventů Katedry sociální práce FF UK Vypracovala: Bc. Jana Bradáčová Obor: Sociální práce Vedoucí práce: Doc. PhDr. Oldřich Matoušek Oponent: PhDr. Milan Sedláček Summary Social work is a profession that in light of the growing number of social problem is going to be indispensable. It is important to be focused not just on the profession itself but also on the educational institutions that are providing the training and education to on-coming social workers. Principal aim of this thesis is to find out what kinds of exercise have students of the Department of Social work of FF UK that graduated in years 2005 to 2008. Further aim was to provide general information about the current position of the Social worker profession and also to provide complex summary about the selected education programs of Social work at Czech Universities. This thesis is dissertating about the profession of the Social worker in general. It is focused on professionalization of Social work in Czech Republic, on its conception as a human science branch and also about the role of the vocational association in this case. It is also providing compact summary about the possibilities of university education in Social work. In total are in Czech Republic 17 Faculties on 11 Universities, where is..

Prevention of School Failure in Kindergartens

Tématem předložené bakalářské práce je prevence školní neúspěšnosti v mateřských školách. Jejím cílem bylo zjistit, jaké metody prevence školní neúspěšnosti dětí jsou nejčastěji v mateřských školách používány.Bakalářská práce byla rozdělena na dvě stěžejní oblasti, na  část teoretickou a na část praktickou. Teoretická část bakalářské práce seznamovala čtenáře s vývojem předškolního dítěte, s oblastmi rizikových faktorů, které ohrožují školní úspěšnost a s metodami prevence a reedukace, které jsou v mateřských školách používány. Praktická část zjišťovala formou 40 dotazníků, jaké metody prevence školní neúspěšnosti jsou v mateřských školách nejčastěji používány. Výsledky ukázaly, že pedagogové mateřských škol pracují s dětmi převážně skupinovou formou, ve smíšených třídách. Většina pedagogů absolvovala kurzy nebo semináře zaměřené na prevenci školní neúspěšnosti. Bylo také zjištěno, že Metoda dobrého startu a program Maxík jsou nejčastěji používané stimulační programy.In this bachelor thesis I deal with prevention of underachievement at nursery schools. Its aim is to detect the most common methods of prevention of underachievement at nursery schools. The bachelor theses consists of two main parts - a theoretical part and a practical part.The theoretical part concentrates on the development of preschool children, including high-risk factors that affect success of children at schools and prevention and reeducation methods that are applied at nursery schools. The practical part has used 40 questionnaires to identify which prevention methods of school underachievement are applied at nursery schools most frequently. The results indicates that nursery school teachers work with children primarily in groups, in mixed classes. Most teachers have successfully completed courses focused on prevention of school underachievement. It also has been found that A good start method and Maxík method are the most frequently used stimulating programmes

Evaluation of the Determination of Dabigatran, Rivaroxaban, and Apixaban in Lupus Anticoagulant-Positive Patients

Background: The effect of direct oral anticoagulants (DOAC) on laboratory tests dependent on the production of their targets, factor IIa and factor Xa, is a well-known problem and can cause both false positive and negative results. In particular, the situation in patients who develop lupus anticoagulant (LA) antibodies is highly complex. To evaluate the effectiveness of DOAC therapy in lupus-positive patients, 31 samples were enrolled in this retrospective study. All patient samples were spiked with three types of DOAC (dabigatran, DABI; rivaroxaban, RIVA; and apixaban, API) in a concentration that significantly influenced the screening test for LA and thus can mask the presence of LA. Subsequently, the DOAC was always unbound by the DOAC-Stop procedure. DOAC levels before and after binding were determined by functional assays, followed by liquid chromatography coupled with mass spectrometry (LC-MS) analysis. Methods: The determination of DOAC levels was performed by direct thrombin assay and determination of anti-Xa activity with specific calibration as functional tests for DABI and xabans (API and RIVA). To determine concentration levels of API, DABI, and RIVA, our in-house LC-MS method was used. Results: The results of LA-positive samples show significant differences between functional tests and the LC-MS method both before and after DOAC binding. Conclusions: The acute findings of the presence of LA-type antibodies fundamentally affects the determination of DOAC by functional tests, and in this case, it is necessary to use LC-MS analysis to determine the true value. If patients treated with DOAC develop LA of medium and higher titers, we do not recommend checking DOAC levels with functional tests

Determination of Thrombogenicity Levels of Various Antiphospholipid Antibodies by a Modified Thrombin Generation Assay in Patients with Suspected Antiphospholipid Syndrome

Antiphospholipid syndrome (APS) is a hypercoagulable state accompanied by the presence of heterogeneous antiphospholipid antibodies (aPL), which nonspecifically affect hemostasis by the presence of lupus anticoagulans (LA), anticardiolipin antibodies (aCL), antibodies against β2-glycoprotein-I (anti-β2GPI), but also non-criteria antibodies such as antibodies against β2-glycoprotein-I domain I (anti-DI), anti-phosphatidylserine/prothrombin (anti-PS/PT), anti-annexin V, and many others. The main target of the antibodies is the activated protein C (APC) system, the elimination of which can manifest itself as a thrombotic complication. The aim of this study was to determine the thrombogenicity of antibodies using a modified protein C-activated thrombin generation assay (TGA) on a group of 175 samples suspected of APS. TGA was measured with/without APC and the ratio of both measurements was evaluated (as for APC resistance), where a cut-off was calculated ≤4.5 (90th percentile) using 21 patients with heterozygous factor V Leiden mutation (FV Leiden heterozygous). Our study demonstrates the well-known fact that multiple positivity of different aPLs is a more severe risk for thrombosis than single positivity. Of the single antibody positivity, LA antibodies are the most serious (p value p value < 0.05). Non-criteria antibodies anti-annexin V and anti-PT/PS has a similar frequency occurrence of thrombogenicity as LA antibodies but without statistical significance or anti-β2GPI1 positivity. The modified TGA test can help us identify patients in all groups who are also at risk for recurrent thrombotic and pregnancy complications; thus, long-term prophylactic treatment is appropriate. For this reason, it is proving increasingly beneficial to include the determination antibodies in combination with modified TGA test