Contributo alla conoscenza della flora vascolare della Riserva Naturale Regionale Sentina (Italia Centrale, Marche)

In this work new floristic records for 12 taxa are reported for Natural Regional Reserve Sentina. Particularly 3 are new to Marche region (Cortaderia selloana, Eclipta prostrata, and Potamogeton berchtoldii). The survey was carried out from 2014 to 2015 through field research and collections. Some recorded species are particularly interesting from phytogeographical or conservational point of views as they are very rare in central Italy along the Adriatic coasts

Colorectal Cancer Stage at Diagnosis Before vs During the COVID-19 Pandemic in Italy

IMPORTANCE Delays in screening programs and the reluctance of patients to seek medical attention because of the outbreak of SARS-CoV-2 could be associated with the risk of more advanced colorectal cancers at diagnosis. OBJECTIVE To evaluate whether the SARS-CoV-2 pandemic was associated with more advanced oncologic stage and change in clinical presentation for patients with colorectal cancer. DESIGN, SETTING, AND PARTICIPANTS This retrospective, multicenter cohort study included all 17 938 adult patients who underwent surgery for colorectal cancer from March 1, 2020, to December 31, 2021 (pandemic period), and from January 1, 2018, to February 29, 2020 (prepandemic period), in 81 participating centers in Italy, including tertiary centers and community hospitals. Follow-up was 30 days from surgery. EXPOSURES Any type of surgical procedure for colorectal cancer, including explorative surgery, palliative procedures, and atypical or segmental resections. MAIN OUTCOMES AND MEASURES The primary outcome was advanced stage of colorectal cancer at diagnosis. Secondary outcomes were distant metastasis, T4 stage, aggressive biology (defined as cancer with at least 1 of the following characteristics: signet ring cells, mucinous tumor, budding, lymphovascular invasion, perineural invasion, and lymphangitis), stenotic lesion, emergency surgery, and palliative surgery. The independent association between the pandemic period and the outcomes was assessed using multivariate random-effects logistic regression, with hospital as the cluster variable. RESULTS A total of 17 938 patients (10 007 men [55.8%]; mean [SD] age, 70.6 [12.2] years) underwent surgery for colorectal cancer: 7796 (43.5%) during the pandemic period and 10 142 (56.5%) during the prepandemic period. Logistic regression indicated that the pandemic period was significantly associated with an increased rate of advanced-stage colorectal cancer (odds ratio [OR], 1.07; 95%CI, 1.01-1.13; P = .03), aggressive biology (OR, 1.32; 95%CI, 1.15-1.53; P < .001), and stenotic lesions (OR, 1.15; 95%CI, 1.01-1.31; P = .03). CONCLUSIONS AND RELEVANCE This cohort study suggests a significant association between the SARS-CoV-2 pandemic and the risk of a more advanced oncologic stage at diagnosis among patients undergoing surgery for colorectal cancer and might indicate a potential reduction of survival for these patients

How future surgery will benefit from SARS-COV-2-related measures: a SPIGC survey conveying the perspective of Italian surgeons

COVID-19 negatively affected surgical activity, but the potential benefits resulting from adopted measures remain unclear. The aim of this study was to evaluate the change in surgical activity and potential benefit from COVID-19 measures in perspective of Italian surgeons on behalf of SPIGC. A nationwide online survey on surgical practice before, during, and after COVID-19 pandemic was conducted in March-April 2022 (NCT:05323851). Effects of COVID-19 hospital-related measures on surgical patients' management and personal professional development across surgical specialties were explored. Data on demographics, pre-operative/peri-operative/post-operative management, and professional development were collected. Outcomes were matched with the corresponding volume. Four hundred and seventy-three respondents were included in final analysis across 14 surgical specialties. Since SARS-CoV-2 pandemic, application of telematic consultations (4.1% vs. 21.6%; p < 0.0001) and diagnostic evaluations (16.4% vs. 42.2%; p < 0.0001) increased. Elective surgical activities significantly reduced and surgeons opted more frequently for conservative management with a possible indication for elective (26.3% vs. 35.7%; p < 0.0001) or urgent (20.4% vs. 38.5%; p < 0.0001) surgery. All new COVID-related measures are perceived to be maintained in the future. Surgeons' personal education online increased from 12.6% (pre-COVID) to 86.6% (post-COVID; p < 0.0001). Online educational activities are considered a beneficial effect from COVID pandemic (56.4%). COVID-19 had a great impact on surgical specialties, with significant reduction of operation volume. However, some forced changes turned out to be benefits. Isolation measures pushed the use of telemedicine and telemetric devices for outpatient practice and favored communication for educational purposes and surgeon-patient/family communication. From the Italian surgeons' perspective, COVID-related measures will continue to influence future surgical clinical practice

Valutazione delle performance di un algoritmo per la quantificazione della pressione portale epatica da ecografia con mezzo di contrasto

La misurazione del gradiente pressorio venoso (HVPG) viene utilizzata per diagnosticare la gravità della malattia del fegato ma si tratta di una pratica invasiva e che non può essere effettuata in tutti i pazienti. Per questo motivo sono state studiate nuove metodiche per riuscire ad analizzare la cirrosi, una tra le quali l’indagine ecografica. Un progetto in fase di svolgimento (progetto CLEVER) è stato avviato per riuscire a sviluppare, validare e trasferire nella pratica clinica un nuovo sistema basato sull'analisi di immagini ecografiche con mezzo di contrasto al fine di valutare la gravità della degenerazione della rete vascolare causata dalla cirrosi. L'obiettivo principale della ricerca è quello di sviluppare uno strumento completamente automatico per l'analisi in tempo reale della rete vascolare del fegato in grado di valutare la connettività vascolare e quantificare il grado di squilibrio della rete

Sviluppo di un coating edibile arricchito con estratti di caffè

Il settore del food packaging sta attualmente affrontando diverse sfide, tra cui la riduzione degli sprechi alimentari e dell’impatto ambientale. L'impiego di imballaggi edibili rappresenta una promettente strategia per prolungare la durata di conservazione degli alimenti e ridurre gli sprechi. Inoltre, l'utilizzo di scarti e sottoprodotti dell'industria alimentare per valorizzare gli imballaggi edibili è in linea con i principi dell'economia circolare. Nella lavorazione del caffè, dove solo il 10% delle bacche viene utilizzato per la preparazione della bevanda, si generano molti scarti lungo le varie fasi della produzione che possono essere valorizzati in diversi modi. L'obiettivo di questa tesi è stato quello di valorizzare fondi di caffè esausto (SCG) per ottenere estratti con cui attivare coating edibili destinati alla conservazione di frutta di IV gamma. Sono stati ottenuti estratti SCG liofilizzati utilizzando due metodi di estrazione: solido-liquido in acqua calda ed estrazione in acqua assistita con ultrasuoni (US). Gli estratti liofilizzati sono stati caratterizzati per il loro contenuto in polifenoli e per l’attività antiossidante (FRAP, DPPH, ABTS). Gli estratti SCG ottenuti con US hanno mostrato una resa di estrazione superiore ma complessivamente una minore attività antiossidante rispetto agli estratti ottenuti senza US. È stata inoltre messa a punto una formulazione di coating a base di alginato di sodio e soluzione di cross-linking con ascorbato di calcio da attivare con gli estratti SCG liofilizzati ottenuti. Le caratteristiche protettive della soluzione di coating sono state testate preliminarmente su spicchi di mela durante test rapidi di conservazione refrigerata

[Additions to the vascular flora of Natural Regional Reserve Sentina (central Italy, Marche)]

AIn this work new floristic records for 12 taxa are reported for Natural Regional Reserve Sentina. Particularly 3 are new to Marche region (Cortaderia selloana, Eclipta prostrata, and Potamogeton berchtoldii). The survey was carried out from 2014 to 2015 through field research and collections. Some recorded species are particularly interesting from phytogeographical or conservational point of views as they are very rare in central Italy along the Adriatic coasts

Monitoring of threatened plants in the ‘Sentina’ Natural Reserve (Marche, Italy).

Among the plants of conservation interest in the ‘Sentina’ Natural Reserve, monitoring was carried out based on the red lists, the plant rarity, and the importance of their habitat. The following taxa were chosen for the monitoring from 2007 to 2012: Ranunculus peltatus subsp. baudotii, Euphorbia terracina, Carex extensa, Rumex palustris, Elytrigia juncea subsp. juncea, Spartina versicolor, Eryngium maritimum, Artemisia caerulescens subsp. caerulescens, Medicago marina, Salicornia perennans subsp. perennans, Crypsis schoenoides, Crypsis aculeata, and Halimione portulacoides. Following this monitoring, management activities that will be useful for the conservation of the flora of the Natural Reserve are here proposed

Flora della Riserva Naturale Regionale Sentina . Atlante fotografico delle piante vascolari.

Viene presentata la Flora vascolare della Riserva Naturale Regionale Sentina (Marche