A PTSD symptoms trajectory mediates between exposure levels and emotional support in police responders to 9/11: A growth curve analysis

Exposure to the terrorist attack on the World Trade Center (WTC) on 9/11/2001 resulted in continuing stress experience manifested as Posttraumatic Stress Disorder (PTSD) Symptoms in a minority of the police responders. The WTC Health Registry has followed up a large number of individuals, including police officers, at three waves of data collection from 2003 to 2011. This analysis examines the relationship between initial exposure levels, long-term PTSD symptoms, and subsequent emotional support among police responders

Delayed self-recognition in children with autism spectrum disorder.

This study aimed to investigate temporally extended self-awareness (awareness of one’s place in and continued existence through time) in autism spectrum disorder (ASD), using the delayed self-recognition (DSR) paradigm (Povinelli et al., Child Development 67:1540–1554, 1996). Relative to age and verbal ability matched comparison children, children with ASD showed unattenuated performance on the DSR task, despite showing significant impairments in theory-of-mind task performance, and a reduced propensity to use personal pronouns to refer to themselves. The results may indicate intact temporally extended self-awareness in ASD. However, it may be that the DSR task is not an unambiguous measure of temporally extended self-awareness and it can be passed through strategies which do not require the possession of a temporally extended self-concept

Barium Ions for Quantum Computation

Individually trapped 137Ba+ in an RF Paul trap is proposed as a qubit ca ndidate, and its various benefits are compared to other ionic qubits. We report the current experimental status of using this ion for quantum computation. Fut ure plans and prospects are discussed

Lattice QCD calculation of Bˉ→Dlνˉ\bar{B}\to Dl\bar{\nu} decay form factors at zero recoil

A lattice QCD calculation of the $\bar{B}\to Dl\bar{\nu}$ decay form factors is presented. We obtain the value of the form factor $h_+(w)$ at the zero-recoil limit $w=1$ with high precision by considering a ratio of correlation functions in which the bulk of the uncertainties cancels. The other form factor $h_-(w)$ is calculated, for small recoil momenta, from a similar ratio. In both cases, the heavy quark mass dependence is observed through direct calculations with several combinations of initial and final heavy quark masses. Our results are $h_+(1) = 1.007(6)(2)(3)$ and $h_-(1)=-0.107(28)(04)(^{10}_{30})$. For both the first error is statistical, the second stems from the uncertainty in adjusting the heavy quark masses, and the last from omitted radiative corrections. Combining these results, we obtain a precise determination of the physical combination $F_{B\to D}(1)=1.058(^{20}_{17})$, where the mentioned systematic errors are added in quadrature. The dependence on lattice spacing and the effect of quenching are not yet included, but with our method they should be a fraction of $F_{B\to D}-1$.Comment: 32 pp, 10 figs; final, published versio

The Semileptonic Decays B→πlνB\to\pi l\nu and D→πlνD\to\pi l\nu from Lattice QCD

We present a lattice QCD calculation of the form factors and differential decay rates for semileptonic decays of the heavy-light mesons $B$ and $D$ to the final state $\pi l\nu$. The results are obtained with three methodological improvements over previous lattice calculations: a matching procedure that reduces heavy-quark lattice artifacts, the first study of lattice-spacing dependence, and the introduction of kinematic cuts to reduce model dependence. We show that the main systematics are controllable (within the quenched approximation) and outline how the calculations could be improved to aid current experiments in the determination of~$|V_{ub}|$ and~$|V_{cd}|$.Comment: 35 pp, 12 fig

The Science Advantage of a Redder Filter for WFIRST

WFIRST will be capable of providing Hubble-quality imaging performance over several thousand square degrees of the sky. The wide-area, high spatial resolution survey data from WFIRST will be unsurpassed for many decades into the future. With the current baseline design, the WFIRST filter complement will extend from the bluest wavelength allowed by the optical design to a reddest filter (F184W) that has a red cutoff at 2.0 microns. In this white paper, we outline some of the science advantages for adding a K_s filter with a 2.15 micron central wavelength in order to extend the wavelength coverage for WFIRST as far to the red as the possible given the thermal performance of the observatory and the sensitivity of the detectors

LASSO: Large Adaptive optics Survey for Substellar Objects using the new SAPHIRA detector on Robo-AO

We report on initial results from the largest infrared AO direct imaging survey searching for wide orbit (>100 AU) massive exoplanets and brown dwarfs as companions around young nearby stars using Robo-AO at the 2.1-m telescope on Kitt Peak, Arizona. The occurrence rates of these rare substellar companions are critical to furthering our understanding of the origin of planetary-mass companions on wide orbits. The observing efficiency of Robo-AO allows us to conduct a survey an order of magnitude larger than previously possible. We commissioned a low-noise high-speed SAPHIRA near-infrared camera to conduct this survey and report on its sensitivity, performance, and data reduction process.Comment: 10 pages, 7 figures, SPIE conference proceeding

Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis.

ObjectiveBronchodilator responsiveness (BDR) is prevalent in COPD, but its clinical implications remain unclear. We explored the significance of BDR, defined by post-bronchodilator change in FEV1 (BDRFEV1) as a measure reflecting the change in flow and in FVC (BDRFVC) reflecting the change in volume.MethodsWe analyzed 2974 participants from a multicenter observational study designed to identify varying COPD phenotypes (SPIROMICS). We evaluated the association of BDR with baseline clinical characteristics, rate of prospective exacerbations and mortality using negative binomial regression and Cox proportional hazards models.ResultsA majority of COPD participants exhibited BDR (52.7%). BDRFEV1 occurred more often in earlier stages of COPD, while BDRFVC occurred more frequently in more advanced disease. When defined by increases in either FEV1 or FVC, BDR was associated with a self-reported history of asthma, but not with blood eosinophil counts. BDRFVC was more prevalent in subjects with greater emphysema and small airway disease on CT. In a univariate analysis, BDRFVC was associated with increased exacerbations and mortality, although no significance was found in a model adjusted for post-bronchodilator FEV1.ConclusionWith advanced airflow obstruction in COPD, BDRFVC is more prevalent in comparison to BDRFEV1 and correlates with the extent of emphysema and degree of small airway disease. Since these associations appear to be related to the impairment of FEV1, BDRFVC itself does not define a distinct phenotype nor can it be more predictive of outcomes, but it can offer additional insights into the pathophysiologic mechanism in advanced COPD.Clinical trials registrationClinicalTrials.gov: NCT01969344T4

When prototypes are not best: Judgments made by children with autism

The current study used a factorial comparison experimental design to investigate conflicting findings on prototype effects shown by children with autism (Klinger & Dawson, 2001; Molesworth, Bowler, & Hampton, 2005). The aim was to see whether children with high –functioning autism could demonstrate prototype effects via categorization responses and whether failure to do so was related to difficulty understanding ambiguous task demands. Two thirds of the autism group did show an effect. The remainder, a sub-group defined by performance on a control task, did not. The discussion focuses on the influence of heterogeneity within the autism group and the ability to resolve ambiguity on task performance. Finally, an alternative experimental design is recommended for further research into these issues