Dynamic behavior and microstructural properties of cancellous bone

The aim of the presented study is to identify some properties of the dynamic behavior of the cancellous bone and to identify the link between this mechanical behavior and the microstructural properties. 7 cylinders of bovine cancellous bone (diameter 41 mm, thickness 14 mm) were tested in quasi static loading (0.001 s-1), 8 in dynamic loading (1000 s-1) and 10 in dynamic loading (1500 s-1) with a confinement system. All the specimens were submitted to imaging before the tests (pQCT) in order to indentify two microstructural properties: Bone Volume / Total Volume ? BV/TV ? and Trabeculae Thickness ? Tb.Th. The behavior of bovine cancellous bone under compression exhibits a foam-type behavior over the whole range of strain rates explored in this study. The results show that for the quasi-static tests only the stresses are correlated with BV/TV. For the unconfined dynamic tests, the yield stress is correlated to BV/TV and the plateau stress to BV/TV and Tb.Th. For the confined tests, only the plateau stress is correlated to BV/TV and Tb.Th. The effect of strain rate is an increase of the yield stress and the plateau stress. The confinement has an effect on the measured values of compression stresses that confirms the importance of marrow flow in the overall behavior

Links between microstructural properties of cancellous bone and its mechanical response to different strain rates.

Not applicabl

Correlations between cancellous bone architecture and its dynamic behaviour

Previous studies showed that in vivo evaluation of the fracture risk of cancellous bone can be assessed by identifying the relationships between its microarchitecture description extracted from clinical imaging and its mechanical properties. The mechanical properties under dynamic loadings (with and without confinement) were obtained and compared to quasi-static ones. The architectural parameters of each specimen were extracted from pQCT images and split into four groups: geometry, topology, connectivity and anisotropy. Results show that architectural parameters are strong determinants of mechanical behaviour for the different applied boundary conditions.http://icills2014.org/wp-content/uploads/2014/01/Marrianne-Prot.pd

Links between mechanical behavior of cancellous bone and its microstructural properties under dynamic loading

Previous studies show that in vivo assessment of fracture risk can be achieved by identifying the relationships between microarchitecture description from clinical imaging and mechanical properties. This study demonstrates that results obtained at low strain rates can be extrapolated to loadings with an order of magnitude similar to trauma such as car crashes. Cancellous bovine bone specimens were compressed under dynamic loadings (with and without confinement) and the mechanical response properties were identified, such as Young's modulus, ultimate stress, ultimate strain, and ultimate strain energy. Specimens were previously scanned with pQCT, and architectural and structural microstructure properties were identified, such as parameters of geometry, topology, connectivity and anisotropy. The usefulness of micro-architecture description studied was in agreement with statistics laws. Finally, the differences between dynamic confined and non-confined tests were assessed by the bone marrow influence and the cancellous bone response to different boundary conditions. Results indicate that architectural parameters, such as the bone volume fraction (BV/TV), are as strong determinants of mechanical response parameters as ultimate stress at high strain rates (p-valueo0.001). This study reveals that cancellous bone response at high strain rates, under different boundary conditions, can be predicted from the architectural parameters, and that these relations with mechanical properties can be used to make fracture risk prediction at a determined magnitude

High power proton linacs

<p>Part 1 of the lecture focuses on</p><ul><li>«Definition» of a high power proton linac (HPPL) and range of applications</li><li>HPPL for neutron source</li><li>HPPL for radioactive Ion beams production</li><li>HPPL for nuclear waste treatment</li></ul><p>Part 2 of the lecture focuses on</p><ul><li>Superconducting cavities for HPPL : basics, advantages, performances overview and technological challenges</li></ul&gt

Dynamic behavior and microstructural properties of cancellous bone

International audienceThe aim of the presented study is to identify some properties of the dynamic behavior of the cancellous bone and to identify the link between this mechanical behavior and the microstructural properties. 7 cylinders of bovine cancellous bone (diameter 41 mm, thickness 14 mm) were tested in quasi static loading (0.001 s-1), 8 in dynamic loading (1000 s-1) and 10 in dynamic loading (1500 s-1) with a confinement system. All the specimens were submitted to imaging before the tests (pQCT) in order to indentify two microstructural properties: Bone Volume / Total Volume – BV/TV – and Trabeculae Thickness – Tb.Th. The behavior of bovine cancellous bone under compression exhibits a foam-type behavior over the whole range of strain rates explored in this study. The results show that for the quasi-static tests only the stresses are correlated with BV/TV. For the unconfined dynamic tests, the yield stress is correlated to BV/TV and the plateau stress to BV/TV and Tb.Th. For the confined tests, only the plateau stress is correlated to BV/TV and Tb.Th. The effect of strain rate is an increase of the yield stress and the plateau stress. The confinement has an effect on the measured values of compression stresses that confirms the importance of marrow flow in the overall behavior

Correlations between cancellous bone architecture and its dynamic behavior

International audienc

ESS Spoke Cryomodule and Test Valve Box

International audienceESS project aims being the world’s most powerful neutron source feeding multidisplinary researches. The superconducting part of the ESS linear accelerator includes 28 b=0.5 352.2 MHz SRF niobium double Spoke cavities. Paired in 13 cryomodules and held at 2K in a saturated helium bath those cavities will generate of an accelerating field of 9MV/m. The prototype Spoke cryomodule holds two cavities and their RF power couplers and integrates all the interfaces necessary to be operational within the linac machine. It is now being fabricated and its assembly will be performed with dedicated tooling and procedures in and out of the clean room. This prototype will be tested by the end of 2015 at IPNO site and then at full power at FREIA (Uppsala university) test stand. A valve box has thus been designed to take into account the specific features of this prototype cryomodule and of the cryogenic environments of both test sites. This valve box is also considered as a prototype of the cryogenic distribution of the linac Spoke section. This element will then be used for the tests of the series cryomodules. We propose to present this prototype Spoke cryomodule for ESS and the test valve box

Distribution of calcifications within the meniscal segments.

<p>Distribution of calcifications within the menisci. Each medial or lateral meniscus was divided into anterior, middle and posterior segments for analysis.</p

Distribution of calcifications in the hyaline cartilage of the femoral condyles.

<p>Each condyle was divided into inner, middle and outer thirds for analysis.</p