15 research outputs found
Ăvolution de la rĂ©partition de mise en charge au cours de la rĂ©adaptation chez les personnes prĂ©sentant une hĂ©miparĂ©sie consĂ©cutive Ă un accident vasculaire cĂ©rĂ©bral
Il est connu que les personnes ayant une hĂ©miparĂ©sie Ă la suite dâun accident vasculaire cĂ©rĂ©bral (AVC) prĂ©sentent une mise en charge (MEC) asymĂ©trique lors de la station debout et lors du passage assis Ă debout (PAD). Par contre, peu dâĂ©tudes ont quantifiĂ© lâĂ©volution de la MEC avec la rĂ©adaptation ou la prĂ©cision avec laquelle ces personnes sont capables de la juger. Lâobjectif principal de ce projet Ă©tait dâĂ©tudier lâĂ©volution de la rĂ©partition et la perception de MEC en position debout et lors du PAD chez des personnes hĂ©miparĂ©tiques en rĂ©adaptation fonctionnelle intensive (RFI). Un objectif secondaire Ă©tait dâidentifier les facteurs qui caractĂ©risent les personnes hĂ©miparĂ©tiques les plus asymĂ©triques et les plus atteintes dans leur perception. Cette Ă©tude a Ă©tĂ© menĂ©e auprĂšs de seize participants. Les rĂ©sultats ont dĂ©montrĂ© quâune asymĂ©trie de rĂ©partition de lâappui en faveur du cĂŽtĂ© non parĂ©tique est prĂ©sente dĂšs les premiers mois aprĂšs lâAVC et quâelle persiste malgrĂ© la RFI. Chez les personnes avec une atteinte sĂ©vĂšre de la
fonction motrice, la MEC Ă©tait plus symĂ©trique pour le PAD que la station debout. En termes de perception, les personnes hĂ©miparĂ©tiques Ă©taient capables dâidentifier le cĂŽtĂ© sur lequel ils mettaient plus dâappui mais ils avaient tendance Ă surestimer lâappui sur le cĂŽtĂ© parĂ©tique et donc Ă se juger moins asymĂ©triques quâils ne lâĂ©taient en rĂ©alitĂ©. TrĂšs peu de changements ont Ă©tĂ© observĂ©s lorsque les donnĂ©es au congĂ© Ă©taient comparĂ©es aux donnĂ©es Ă lâentrĂ©e dans lâĂ©tude. En rĂ©ponse Ă lâobjectif secondaire, la fonction motrice du membre infĂ©rieur parĂ©tique Ă©valuĂ©e par le Chedoke et la diffĂ©rence de force des extenseurs entre les genoux Ă©taient les facteurs les plus dĂ©terminants de lâasymĂ©trie et de la perception de MEC. Les rĂ©sultats obtenus constituent donc une Ă©tape supplĂ©mentaire vers la comprĂ©hension de la rĂ©partition asymĂ©trique et les troubles de perception de MEC lors de la station debout et le PAD chez les personnes hĂ©miparĂ©tiques. Il serait intĂ©ressant dans le futur dâexplorer davantage les facteurs susceptibles dâinfluencer lâasymĂ©trie et la perception de MEC et dâobjectiver la relation de cause Ă effet entre ces deux variables en plus de prĂ©ciser lâeffet rĂ©el de lâasymĂ©trie sur la stabilitĂ© posturale.It is well known that people with hemiparesis after stroke have asymmetric weight bearing (WB) when standing and during sit-to-stand (STS). However, few studies have quantified the evolution of WB with rehabilitation or focused on the accuracy with which hemiparetic individuals are able to perceive their WB. The main purpose of this project was to assess the changes, with rehabilitation, in WB distribution and perception of WB during standing position and STS in hemiparetic individuals. A secondary objective was to identify the factors that characterize the most asymmetric hemiparetic individuals and the most affected in their perception. The study was conducted with sixteen participants. The results showed that asymmetric WB is present in the first months after stroke and persists despite rehabilitation. For individuals who had had severe impairment of motor function, WB was more symmetrical during STS than standing. In terms of WB perception, hemiparetic individuals were able to identify the side on which the loading was higher and they generally overestimated the weight under the paretic side. Overall, data at admission and discharge from the study were not different. Furthermore, the motor function of paretic lower limb evaluated by Chedoke and the strength of knee extensors were the most determinant factors of WB and perception. These results can thus be considered as a further step in order to understand the asymmetrical distribution and the impaired perception of WB. It would be interesting in the future to further explore the factors that may influence the perception and asymmetry of WB in order to identify the relationship between these two variables with a specific focus on the impact of WB asymmetry on the patientâs stability in both tasks
Determinants of sit-to-stand tasks in individuals with hemiparesis post stroke: A review
AbstractBackground and purposeThe ability to rise from a chair to reach a standing position is impaired after stroke. This paper aims to review for the first time the factors that impact the ability to rise from a chair and identify recommendations for post-stroke rehabilitation.MethodsIn order to analyse relevant scientific publications (French and English), the search terms âstrokeâ, ârehabilitationâ and âsit-to-standâ (STS and its variations) were used. The initial literature search identified 122 titles and abstracts for full review and 46 were retained because both the junior and senior researchers agreed that they were aligned with the objectives of this review.Results and conclusionDuring STS, most individuals with hemiparesis able to stand independently presented several changes such as lateral deviation of the trunk towards the unaffected side (ipsilesional side), asymmetrical weight bearing (WB) and asymmetry of knee moment forces. Interestingly, the WB asymmetry was observed even before seat-off, when subjects with hemiparesis still had their thighs in contact with the chair suggesting a planned strategy. Among other interesting results, the time to execute the STS was longer than in controls and influenced by the sensorimotor deficits. A greater risk of falling was observed with a need for more time to stabilize the body during STS and especially during the extension phase. Some rehabilitation interventions may be effective in improving STS duration, WB symmetry and the ability to stand independently with repeated practice (mentally or physically) of STS tasks. However, more research is essential to further investigate effects of specific training protocols and pursue better understanding of this complex and demanding task, particularly for stroke patients who need assistance during this transfer
Choice of the functional monomer of molecularly imprinted polymers: Does it rely on strong acid-base or hydrogen bonding interactions?
International audienceThe choice of the functional monomer is a key point in the design of molecularly imprinted polymers (MIPs) because its directional interactions with template molecules are required to form molecular imprints acting as selective recognition sites for adsorption. Methacrylic acid (MAA) has very often been employed as a functional monomer for imprinting basic template molecules. Strong acid-base interactions lead to H+ transfer and weak hydrogen bonding between the products of the acid-base reaction. The weakly acidic acrylamide (AA) has shown stronger hydrogen-bonding interactions with histamine (HA) than MAA. Interactions between HA and the functional monomers have been investigated by means of 1H NMR spectroscopy yielding the stoichiometry and complexation constants of their complex species. Adsorption isotherms of HA to both MAA- and AA-based MIPs and their modeling showed a higher selective binding of HA to the AA-based MIP
Epidemiology and clinical profile of pathogens responsible for the hospitalization of children in Sousse area, Tunisia
<div><p>This study aimed to identify a broad spectrum of respiratory pathogens from hospitalized and not-preselected children with acute respiratory tract infections in the Farhat Hached University-hospital of Sousse, Tunisia. Between September 2013 and December 2014, samples from 372 children aged between 1 month and 5 years were collected, and tested using multiplex real-time RT-PCR by a commercial assay for 21 respiratory pathogens. In addition, samples were screened for the presence of <i>Streptococcus pneumoniae</i> 16S rDNA using real-time PCR. The viral distribution and its association with clinical symptoms were statistically analyzed. Viral pathogens were detected in 342 (91.93%) of the samples of which 28.76% were single positive and 63.17% had multiple infections. The most frequent detected viruses were rhinovirus (55.64%), respiratory syncytial virus A/B (33.06%), adenovirus (25.00%), coronavirus NL63, HKU1, OC43, and 229E (21.50%), and metapneumovirus A/B (16.12%). Children in the youngest age group (1â3 months) exhibited the highest frequencies of infection. Related to their frequency of detection, RSV A/B was the most associated pathogen with patientâs demographic situation and clinical manifestations (p<0.05). Parainfluenza virus 1â4 and parechovirus were found to increase the risk of death (p<0.05). Adenovirus was statistically associated to the manifestation of gastroenteritis (p = 0.004). Rhinovirus infection increases the duration of oxygen support (p = 0.042). Coronavirus group was statistically associated with the manifestation of bronchiolitis (p = 0.009) and laryngitis (p = 0.017). <i>Streptococcus pneumoniae</i> DNA was detected in 143 (38.44%) of tested samples. However, only 53 samples had a concentration of C-reactive protein from equal to higher than 20 milligrams per liter, and 6 of them were single positive for <i>Streptocuccus pneumoniae</i>. This study confirms the high incidence of respiratory viruses in children hospitalized for acute respiratory tract infections in the Sousse area, Tunisia.</p></div
Impact of individual viral infection on patientâs clinical data and demographic information<sup>a</sup>.
<p>Impact of individual viral infection on patientâs clinical data and demographic information<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0188325#t006fn001" target="_blank"><sup>a</sup></a>.</p
Summary of the statistical comparisons between positive viral infection and patientâs medical history, demographic data and clinical manifestations.
<p>Summary of the statistical comparisons between positive viral infection and patientâs medical history, demographic data and clinical manifestations.</p
Summary of the statistical associations comparing single and multiple viral infections with patientâs data.
<p>Summary of the statistical associations comparing single and multiple viral infections with patientâs data.</p
Characteristics of <i>S</i>. <i>pneumoniae</i> infected subjects in relation to viral infection (negative, single and multiple) and CRP concentrations<sup>a</sup>.
<p>Characteristics of <i>S</i>. <i>pneumoniae</i> infected subjects in relation to viral infection (negative, single and multiple) and CRP concentrations<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0188325#t003fn001" target="_blank"><sup>a</sup></a>.</p
Epidemiology and clinical profile of pathogens responsible for the hospitalization of children in Sousse area, Tunisia
Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease
International audienc