257 research outputs found
An analysis of the effectiveness and cost of project security management
This research analyzes the idea of managing information security risk on projects, as well as the effectiveness and costs associated with this kind of management. Organizations today face a myriad of security risks given their increased use of information technology. New solutions to improve information security within organizations large and small need to be researched and analyzed. Review of relevant literature has determined that although organizations are managing security from the top down, there is a lack of security management at the project level and that most project managers and their teams rely on the organizational security measures to keep information secure. The concept of managing security risks at the project level is not well defined and there exists no concrete and widely accepted framework for it. This research examines if managing security at the project level within a multi-tiered defensive strategy can be effective and at what cost. It also seeks to determine if budgeting for security in projects will lead to more secure project assets and products. This qualitative study uses three sources of data to deduce conclusions and recommendations. One, literary sources, two, subject interviews of security and project management professionals, and three, a computerized model built to simulate a defense in depth strategy. The primary finding of this research is that the concept of managing information security in projects is valid, and that doing so will lead to more secure project assets and products. This type of management will increase the security posture of the project itself and the organization as a whole. Recommendations are made by the researcher as to what steps a project manager and the organization above it must take to leverage the management of information security risks on projects
IP Bouncer: An End-User Network Privacy Enhancing Tool
IP Bouncer is a novel IT artifact that exposes unexpected and unwanted network communication initiated by trusted “insider” applications. It closely follows design science guidelines illustrated in the five design principles of the artifact. One of the novel aspects of the design is the key-pair approach used for assessing appropriate or inappropriate network communications. By coupling the context-awareness of the user with online aggregators of blacklists, IP Bouncer offers greater individual and organizational security protection and earlier detection of network anomalies
Electron Beam Treatment for the Removal of 1,4-Dioxane in Water and Wastewater
Electron beam (e-beam) treatment uses accelerated electrons to form oxidizing and reducing radicals when applied to water without the use of external chemicals. In this study, electron beam treatment was used to degrade 1,4-dioxane in several water matrices. Removal improved in the progressively cleaner water matrices and removals as high as 94% to 99% were observed at a dose of 2.3 kGy in secondary effluent. 1,4-dioxane removal was confirmed to be primarily through hydroxyl radical oxidation. The calculated electrical energy per order was found to be 0.53, 0.26, and 0.08 kWh/m3/order for secondary effluent (Avg. total organic carbon (TOC) 9.25 mg/L), granular activated carbon effluent (TOC 3.46 mg/L), and ultrapure water, respectively, with a 70% generation and transfer efficiency applied
Investigation of the Mechanical Performance of Compliant Thermal Barriers
Compliant thermal barriers play a pivotal role in the thermal protection systems of advanced aerospace vehicles. Both the thermal properties and mechanical performance of these barriers are critical in determining their successful implementation. Due to the custom nature of many thermal barriers, designers of advanced spacecraft have little guidance as to the design, selection, and implementation of these elements. As part of an effort to develop a more fundamental understanding of the interrelationship between thermal barrier design and performance, mechanical testing of thermal barriers was conducted. Two different types of thermal barriers with several core insulation density levels ranging from 62 to 141 kg/cu m were investigated. Room-temperature compression tests were conducted on samples to determine load performance and assess thermal barrier resiliency. Results showed that the loading behavior of these thermal barriers was similar to other porous, low-density, compliant materials, such as elastomeric foams. Additionally, the insulation density level had a significant non-linear impact on the stiffness and peak loads of the thermal barriers. In contrast, neither the thermal barrier type nor the level of insulation density significantly influenced the room-temperature resiliency of the samples
Clinical Characteristics of Patients with Malignant Pleural Mesothelioma Harboring Somatic BAP1 Mutations
IntroductionGenomic studies of malignant pleural mesothelioma (MPM) have recently identified frequent mutations in the BRCA-associated protein 1(BAP1) gene. In uveal melanoma and clear cell renal cell carcinoma, BAP1 mutations are associated with poor outcomes but their clinical significance in MPM is unknown. We therefore undertook this study to define the characteristics of patients whose MPM tumors harbor somatic BAP1 mutation and to examine the relationship between BAP1 mutation and survival.MethodsWe reviewed the charts of 121 patients with MPM tumors diagnosed between 1991 and 2009 tested for BAP1 mutation, and extracted the following information: age at diagnosis, sex, histology, stage, smoking status, asbestos exposure, family or personal history of malignancy, and treatment including surgery, chemotherapy, and radiation as well as survival status.ResultsTwenty-four of the 121 tumors (20%) harbored somatic BAP1 mutations. The percentage of current or former smokers among cases with BAP1 mutations was significantly higher than in BAP1 wild-type cases, (75% versus 42%; p = 0.006). However, the types of nucleotide substitutions in BAP1 did not suggest that this association was because of a causative role of smoking in BAP1 mutations. No other clinical feature was significantly different among those with and without BAP1 mutations in their MPM. There was also no difference in survival according to somatic BAP1 mutation status.ConclusionThere is no apparent distinct clinical phenotype for MPM with somatic BAP1 mutation. The significance of the more frequent history of smoking among patients with BAP1-mutated MPM warrants further study
Sensemaking and Success in the Transition from Community Colleges to University IS/CS/CE Programs
Increasing the enrollment of women, minority, and other underrepresented populations in undergraduate information systems and computing programs is an important social issue. We explore ways of attracting and retaining community college transfer students—an important source of underrepresented students —by examining their sensemaking efforts as they transition to four-year universities. We conducted a qualitative study to test sensemaking theory and develop recommendations for retaining community college transfer students in undergraduate information systems, computer science, and computer engineering programs
Efficient micromirror confinement of sub-TeV cosmic rays in galaxy clusters
Recent observations suggest a stronger confinement of cosmic rays (CRs) in
certain astrophysical systems than predicted by current CR-transport theories.
We posit that the incorporation of microscale physics into CR-transport models
can account for this enhanced CR confinement. We develop a theoretical
description of the effect of magnetic microscale fluctuations originating from
the mirror instability on macroscopic CR diffusion. We confirm our theory with
large-dynamical-range simulations of CR transport in the intracluster medium
(ICM) of galaxy clusters and kinetic simulations of CR transport in micromirror
fields. We conclude that sub-TeV CR confinement in the ICM is far more
effective than previously anticipated on the basis of Galactic-transport
extrapolations.Comment: Utilizes PIC and MHD simulations, complemented by deep learning for
data analysis. Currently under journal review. Comments welcome
The Effect of Core Configuration on Thermal Barrier Thermal Performance
Thermal barriers and seals are integral components in the thermal protection systems (TPS) of nearly all aerospace vehicles. They are used to minimize heat transfer through interfaces and gaps and protect underlying temperature-sensitive components. The core insulation has a significant impact on both the thermal and mechanical properties of compliant thermal barriers. Proper selection of an appropriate core configuration to mitigate conductive, convective and radiative heat transfer through the thermal barrier is challenging. Additionally, optimization of the thermal barrier for thermal performance may have counteracting effects on mechanical performance. Experimental evaluations have been conducted to better understand the effect of insulation density on permeability and leakage performance, which can significantly impact the resistance to convective heat transfer. The effect of core density on mechanical performance was also previously investigated and will be reviewed. Simple thermal models were also developed to determine the impact of various core parameters on downstream temperatures. An extended understanding of these factors can improve the ability to design and implement these critical TPS components
1089-109 Correlation between angiotensin II receptor subtype 1 and vitronectin receptor in cardiac transplantation
The Need for Laboratory Measurements and Ab Initio Studies to Aid Understanding of Exoplanetary Atmospheres
We are now on a clear trajectory for improvements in exoplanet observations
that will revolutionize our ability to characterize their atmospheric
structure, composition, and circulation, from gas giants to rocky planets.
However, exoplanet atmospheric models capable of interpreting the upcoming
observations are often limited by insufficiencies in the laboratory and
theoretical data that serve as critical inputs to atmospheric physical and
chemical tools. Here we provide an up-to-date and condensed description of
areas where laboratory and/or ab initio investigations could fill critical gaps
in our ability to model exoplanet atmospheric opacities, clouds, and chemistry,
building off a larger 2016 white paper, and endorsed by the NAS Exoplanet
Science Strategy report. Now is the ideal time for progress in these areas, but
this progress requires better access to, understanding of, and training in the
production of spectroscopic data as well as a better insight into chemical
reaction kinetics both thermal and radiation-induced at a broad range of
temperatures. Given that most published efforts have emphasized relatively
Earth-like conditions, we can expect significant and enlightening discoveries
as emphasis moves to the exotic atmospheres of exoplanets.Comment: Submitted as an Astro2020 Science White Pape
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