1,674 research outputs found

    “Do We Owe More to Fellow Nationals? The Particular and Universal Ethics in Bosanquet’s General Will and Miller’s Public Culture”

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    There are significant similarities between Bosanquet’s ethical function of the state and Miller’s defence of nations as communities that generate duties. Bosanquet’s references to the state are predominantly to the nation state (1917a: p. 295), and Miller argues that there are good reasons for states and nations to coincide. More to the point, there are essential similarities in the reasons why these two thinkers believe in the ethical significance of the nation state. Many of their arguments in defence of the state or the nation, respectively, are based on the particularist nature of communities in principle and the nation state in particular. The state, for Bosanquet, has ethical significance because it embodies the general will and the latter can exist only in specific communities with shared experiences and established traditions. The general will is anchored in specific communities, institutions and practices and the state is ‘the largest body which possesses the unity of experience necessary for constituting a general will’ (Bosanquet, 1917a: p. 272). Miller’s commitment to particularist ethics is explicit. Particularism, for him, works on the assumption ‘that memberships and attachments in general have ethical significance’ (Miller, 1995: p. 65). National membership, however, supersedes in ethical significance other memberships for two reasons: existence of public culture and national self-determination

    The DiSC assay - A cost-effective guide to treatment for chronic lymphocytic leukemia?

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    The differential staining cytotoxicity (DISC) assay involves in vitro drug panel testing against patient tumor cells to identify optimal therapy. This observational study investigated whether DISC assay guided treatment could improve outcome in patients with chronic lymphocytic leukemia. A cohort of 178 patients were categorized either as sensitive to drugs in vitro and receiving a sensitive drug in vivo, sensitive in vitro but not treated with a sensitive drug, or having disease resistant to all drugs tested in vitro. Response and survival for these patient categories were compared using multivariate regression techniques. Patients receiving a sensitive drug, compared with those who though having sensitivity did not, had a higher remission rate (odds ratio, 6.5; 95% CI, 2.91-14.53) and reduced death rate (hazard ratio, 0.29; 95% CI, 0.16-0.53). Having adjusted for all known confounding factors, the results suggest that in vitro drug sensitivity is an important independent prognostic variable to include in future trials, and that the DiSC assay may be a cost-effective use of health resources: the estimated incremental cost-effectiveness was $1,470 per life-year gained. A randomized controlled trial is required to confirm the benefit and estimate reliably the potential impact of assay-guided choice of therapy

    Brave New Worlds, Capabilities and the Graduates of Tomorrow

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    In 'What is Enlightenment?' Foucault poses the question: 'How can the growth of capabilities be disconnected from the intensification of power relations?' This article revisits that question by raising critical questions about graduate capabilities. Its aim is to reflect, and to prompt reflection, on the complexities of the definition, implementation and evaluation of capabilities-based curriculum in the discipline of cultural studies and in the higher education sector more broadly. It asks what types of graduates are being ‘produced' by universities and for what purposes? Does cultural studies construct the student subject differently from institutional graduate capability frameworks? What is the role, if any, of higher education in the development of capabilities such as ethical practice or moral standards? What of the principles that are demonstrated in institutional graduate capabilities (sustainability etc)? Are these universal values? What relations of power and processes of normalisation underpin the ‘education revolution’ of capabilities-based curriculum

    COMPARISON—IN PSYCHOLOGY AND IN LOGIC

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    Watchwords: The Names of Christ

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    Watchwords: The Names of Christ Almighty Babe Bread Bride Groom Branch Captain Consolation Christ Cornerstone Covert Counsellor Creditor Dew Desire of all the Nations Door Eternal Life Express Image of His Father Emmanuel Ensign Eagle Foundation Feeder Faithful Witness Fountain Flesh Friend of Sinners Gift Guide Glorious God Manifested in the Flesh Head Holy Child Husband Horn Highest Habitation Help Jesus Jah Judge King Leader Life Lion Ladder of Jacob Lovely Long Suffering Love Lamb Merciful Messenger Messiah Melchisedec Nazarene Ointment Prophet Purifier Propitiation Priest Passover Prince of Life Physician Rose of Sharon Rock Refuge Sun Shepherd Tree of Life Vine Christ the Wisdom of Go

    Congenital Epulis: A Case Report and Estimation of Incidence

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    Congenital Epulis, also known as Neumann's tumour, is a rare congenital growth affecting the gingival mucosa of neonates. It is benign condition, seen more frequently in females, with multiple Epuli occurring in only 10% of cases. The cause and origin of Congenital Epulis remains unclear. In this article we present a case report of an otherwise healthy female neonate with two Congenital Epuli arising from the upper and lower gingival margin, which were successfully treated with surgical excision. We also present a review of the literature and an estimation of the incidence of Congenital Epulis based on our institutions figures, of 0.0006% (upper 95% confidence interval: 0.0035%)
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