Why do public responses to CCUS matter if CO₂ is stored offshore?

Social decision makin

D6.1.1: Informed public opinion about industrial CCS in the UK and the Netherlands (ALIGN-CCUS)

Horizon 2020(H2020)691712Social decision makin

D6.2.2: Community compensation and engagement: report on best practices and closing of knowledge gaps (ALIGN-CCUS)

Horizon 2020(H2020)691712Social decision makin

The city as laboratory. Academics, students, and policy makers address urban environmental challenges together

Health and self-regulatio

The city as laboratory. Academics, students, and policy makers address urban environmental challenges together

Health and self-regulatio

D6.3.2: Developing and testing new core messages (ALIGN-CCUS)

Horizon 2020(H2020)691712Social decision makin

Novel loci associated with usual sleep duration: The CHARGE Consortium Genome-Wide Association Study

Contains fulltext : 160002.pdf (publisher's version ) (Closed access)Usual sleep duration is a heritable trait correlated with psychiatric morbidity, cardiometabolic disease and mortality, although little is known about the genetic variants influencing this trait. A genome-wide association study (GWAS) of usual sleep duration was conducted using 18 population-based cohorts totaling 47[thinsp]180 individuals of European ancestry. Genome-wide significant association was identified at two loci. The strongest is located on chromosome 2, in an intergenic region 35- to 80-kb upstream from the thyroid-specific transcription factor PAX8 (lowest P=1.1 [times] 10-9). This finding was replicated in an African-American sample of 4771 individuals (lowest P=9.3 [times] 10-4). The strongest combined association was at rs1823125 (P=1.5 [times] 10-10, minor allele frequency 0.26 in the discovery sample, 0.12 in the replication sample), with each copy of the minor allele associated with a sleep duration 3.1[thinsp]min longer per night. The alleles associated with longer sleep duration were associated in previous GWAS with a more favorable metabolic profile and a lower risk of attention deficit hyperactivity disorder. Understanding the mechanisms underlying these associations may help elucidate biological mechanisms influencing sleep duration and its association with psychiatric, metabolic and cardiovascular disease.8 p