Digital phase-locked loops tracked by a relay sensor

An optimal algorithm is presented for tracking the phase of a slowly modulating signal by means of digital sampling of its sign. Error bounds and a numerical illustration are given

Short report: molecular markers associated with Plasmodium falciparum resistance to sulfadoxine-pyrimethamine in the Democratic Republic of Congo.

Sulfadoxine-pyrimethamine (SP) is the first line antimalarial treatment in the Democratic Republic of Congo. Using polymerase chain reaction, we assessed the prevalence of mutations in the dihydrofolate reductase (dhfr) (codons 108, 51, 59) and dihydropteroate synthase (dhps) (codons 437, 540) genes of Plasmodium falciparum, which have been associated with resistance to pyrimethamine and sulfadoxine, respectively. Four hundred seventy-four patients were sampled in Kilwa (N = 138), Kisangani (N = 112), Boende (N = 106), and Basankusu (N = 118). The proportion of triple mutations dhfr varied between sites but was always > 50%. The proportion of dhps double mutations was < 20%, with some sites as low as 0.9%. A quintuple mutation was present in 12.8% (16/125) samples in Kilwa; 11.9% (13/109) in Kisangani, 2.9% (3/102) in Boende, and 0.9% (1/112) in Basankusu. These results suggest high resistance to pyrimethamine alone or combined with sulfadoxine. Adding artesunate to SP does not seem a valid alternative to the current monotherapy

Hadron Properties with FLIC Fermions

The Fat-Link Irrelevant Clover (FLIC) fermion action provides a new form of nonperturbative O(a)-improvement in lattice fermion actions offering near continuum results at finite lattice spacing. It provides computationally inexpensive access to the light quark mass regime of QCD where chiral nonanalytic behaviour associated with Goldstone bosons is revealed. The motivation and formulation of FLIC fermions, its excellent scaling properties and its low-lying hadron mass phenomenology are presented.Comment: 29 pages, 13 figures, 6 tables. Contribution to lecure notes in 2nd Cairns Topical Workshop on Lattice Hadron Physics 2003 (LHP 2003), Cairns, Australia, 22-30 Jul 200

Peer victimization in Dutch school classes of four- to five-year-olds: Contributing factors at the school level

This research was designed to examine how factors within young children's environment (e.g., school factors, neighborhood) contribute to explaining peer victimization. The sample comprised 2,003 children (between 4 and 5 years of age) from 98 classrooms in 23 elementary schools in the Netherlands. Teachers were asked to complete a questionnaire on exposure to victimization for each child. Multilevel analyses revealed that gender and social climate of the school were directly related to victimization. Furthermore, results indicated that peer victimization in boys was less prevalent when they attended smaller schools. In low-SES neighborhoods victimization scores were significantly lower when schools had implemented clear antibullying policies. Finally, variation among school classes appeared to be strongly associated with victimization, even more so than variation among schools. These findings support broadening the focus beyond the individual child at risk. © 2009 by The University of Chicago. All rights reserved

Quasi-periodic oscillations in accreting magnetic white dwarfs: I. Observational constraints in X-ray and optical

International audienceQuasi-periodic oscillations (QPOs) are observed in the optical flux of some polars with typical periods of 1 to 3 s but none have been observed yet in X-rays where a significant part of the accreting energy is released. QPOs are expected and predicted from shock oscillations. Most of the polars have been observed by the XMM-Newton satellite. We made use of the homogeneous set of observations of the polars by XMM-Newton to search for the presence of QPOs in the (0.5–10 keV) energy range and to set significant upper limits for the brightest X-ray polars. We extracted high time-resolution X-ray light curves by taking advantage of the 0.07 s resolution of the EPIC-PN camera. Among the 65 polars observed with XMM-Newton from 1998 to 2012, a sample of 24 sources was selected on the basis of their counting rate in the PN instrument to secure significant limits. We searched for QPOs using Fast Fourier Transform (FFT) methods and defined limits of detection using statistical tools. Among the sample surveyed, none shows QPOs at a significant level. Upper limits to the fractional flux in QPOs range from 7% to 71%. These negative results are compared to the detailed theoretical predictions of numerical simulations based on a 2D hydrodynamical code presented in Paper II. Cooling instabilities in the accretion column are expected to produce shock quasi-oscillations with a maximum amplitude reaching ~40% in the bremsstrahlung (0.5–10 keV) X-ray emission and ~20% in the optical cyclotron emission. The absence of X-ray QPOs imposes an upper limit of ~(5–10) g cm-2 s-1 on the specific accretion rate but this condition is found inconsistent with the value required to account for the amplitudes and frequencies of the observed optical QPOs. This contradiction outlines probable shortcomings with the shock instability model

A Search for Exozodiacal Dust and Faint Companions Near Sirius, Procyon, and Altair with the NICMOS Coronagraph

We observed Sirius, Altair, and Procyon with the NICMOS Coronagraph on the Hubble Space Telescope to look for scattered light from exozodiacal dust and faint companions within 10 AU from these stars. We did not achieve enough dynamic range to surpass the upper limits set by IRAS on the amount of exo-zodiacal dust in these systems, but we did set strong upper limits on the presence of nearby late-type and sub-stellar companions.Comment: 10 pages, 4 figure

A New Shear Estimator for Weak Lensing Observations

We present a new shear estimator for weak lensing observations which properly accounts for the effects of a realistic point spread function (PSF). Images of faint galaxies are subject to gravitational shearing followed by smearing with the instrumental and/or atmospheric PSF. We construct a `finite resolution shear operator' which when applied to an observed image has the same effect as a gravitational shear applied prior to smearing. This operator allows one to calibrate essentially any shear estimator. We then specialize to the case of weighted second moment shear estimators. We compute the shear polarizability which gives the response of an individual galaxy's polarization to a gravitational shear. We then compute the response of the population of galaxies, and thereby construct an optimal weighting scheme for combining shear estimates from galaxies of various shapes, luminosities and sizes. We define a figure of merit --- an inverse shear variance per unit solid angle --- which characterizes the quality of image data for shear measurement. The new method is tested with simulated image data. We discuss the correction for anisotropy of the PSF and propose a new technique involving measuring shapes from images which have been convolved with a re-circularizing PSF. We draw attention to a hitherto ignored noise related bias and show how this can be analyzed and corrected for. The analysis here draws heavily on the properties of real PSF's and we include as an appendix a brief review, highlighting those aspects which are relevant for weak lensing.Comment: 39 pages, 9 figure

On the Invariant Theory of Weingarten Surfaces in Euclidean Space

We prove that any strongly regular Weingarten surface in Euclidean space carries locally geometric principal parameters. The basic theorem states that any strongly regular Weingarten surface is determined up to a motion by its structural functions and the normal curvature function satisfying a geometric differential equation. We apply these results to the special Weingarten surfaces: minimal surfaces, surfaces of constant mean curvature and surfaces of constant Gauss curvature.Comment: 16 page