The effect of COVID-19 pandemic on daily oncology clinical practice

COvid 19 pandemic created several problems in the organisation of oncological clinics, but some of these changes might actually be beneficia

Experimental evidence of self-localized and propagating spin wave modes in obliquely magnetized current-driven nanocontacts

Through detailed experimental studies of the angular dependence of spin wave excitations in nanocontact-based spin-torque oscillators, we demonstrate that two distinct spin wave modes can be excited, with different frequency, threshold currents and frequency tuneability. Using analytical theory and micromagnetic simulations we identify one mode as an exchange-dominated propagating spin wave, and the other as a self-localized nonlinear spin wave bullet. Wavelet-based analysis of the simulations indicates that the apparent simultaneous excitation of both modes results from rapid mode hopping induced by the Oersted field.Comment: 5 pages, 3 figure

An efficient tool for the assisted design of SAR ADCs capacitive DACs

The optimal design of SAR ADCs requires the accurate estimate of nonlinearity and parasitic capacitance effects in the feedback charge redistribution DAC. Since both contributions depend on the specific array topology, complex calculations, custom modeling and heavy simulations in common circuit design environments are often required. This paper presents a MATLAB-based numerical environment to assist the design of the charge redistribution DACs adopted in SAR ADCs. The tool performs both parametric and statistical simulations taking into account capacitive mismatch and parasitic capacitances computing both differential and integral nonlinearity (DNL, INL). An excellent agreement is obtained with the results of circuit simulators (e.g. Cadence Spectre) featuring up to 10^4 shorter simulation time, allowing statistical simulations that would be otherwise impracticable. The switching energy and SNDR degradation due to static nonlinear effects are also estimated. Simulations and measurements on three designed and two fabricated prototypes confirm that the proposed tool can be used as a valid instrument to assist the design of a charge redistribution SAR ADC and to predict its static and dynamic metrics

Treatment of Fournier's Gangrene with Combination of Vacuum-Assisted Closure Therapy, Hyperbaric Oxygen Therapy, and Protective Colostomy

Fournier's gangrene is a rare process which affects soft tissue in the genital and perirectal area. It can also progress to all different stages of sepsis, and abdominal compartment syndrome can be one of its complications. Two patients in septic shock due to Fournier gangrene were admitted to the Intensive Care Unit of Emergency Department. In both cases, infection started from the scrotum and the necrosis quickly involved genitals, perineal, and inguinal regions. Patients were treated with surgical debridement, protective colostomy, hyperbaric oxygen therapy, and broad-spectrum antibacterial chemotherapy. Vacuum-assisted closure (VAC) therapy was applied to the wound with the aim to clean, decontaminate, and avoid abdominal compartmental syndrome development. Both patients survived and were discharged from Intensive Care Unit after hyperbaric oxygen therapy cycles and abdominal closure

Advanced European Re-Entry System Based on Inflatable Heat Shields: Detailed Design (EFESTO project)

The European Union H2020 EFESTO project is coordinated by DEIMOS Space with the end goals of improving the European TRL of Inflatable Heat Shields for re-entry vehicles (from 3 to 4/5) and paving the way towards further improvements (TRL 6 with a future In-Orbit Demonstrator, IOD). This paper presents the project objectives and the initial results of the detailed design of atmospheric entry missions based on the applications of advanced thermal protection systems implementing inflatable heat shields (flexible TPS and inflatable structures), according to aerothermodynamics constraints for future in-orbit demonstration. Placing the future IOD mission in the context of ongoing and future efforts in the European context is also one of the project goals. Two key applications, Mars Robotic Exploration and Reusable Small Launchers Upper Stages, have been identified. For the Mars Application, the robotic exploration mission class resulted in a 10 m diameter Hypersonic Inflatable Aerodynamic Decelerator (HIAD) class, combined with Supersonic Retro-Propulsion (SRP, activated about Mach 2.3) to deliver about 2800 kg of payload at MOLA +2 km. For the Earth Application, the VEGA upper stage (AVUM) has been selected as baseline case study. The current mission foresees a deorbiting from SSO orbit, a controlled entry phase (BC of about 30 kg/m2) and combines the use of a HIAD (4.5m diameter class) with parachutes and parafoil for Mid-Air-Capturing (MAR) with a helicopter. Beyond feasibility of the entry mission phase and system design with an inflated IAD, integration aspects have a key impact in the specific design solutions adopted, due to the nature of an inflatable heatshield. For both considered application cases feasible architectures are developed responding to the challenge of integrating the HIAD into the system in compliance with geometric and functional requirements. While the HIAD in folded state prior to inflation must fit in the available volume, it has limitations with respect to the density imposing a minimum cross section of the stowage volume. Simultaneously requirements with respect to the centre of gravity position during re-entry with an inflated HIAD must be respected for stability and controllability reasons. Other architectural considerations such as payload integration for the application on a launcher upper stage must be considered. Finally, heat loads constraints are considered for the trajectory and TPS deign choices due to important fluid-structure interactions. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 821801

Elongated styloid process evaluation on digital panoramic radiograph in a North Italian population

The aim of this study is to evaluate the prevalence of elongated styloid process in digital panoramic radiographs in a North Italian population in relation to age, gender and side. This study was performed as a retrospective analysis on digital panoramic radiographs of 600 (271 males and 329 females) Italian patients between 6 and 87 years old. The styloid process length were measured using the measuring tool of Sidexis Software. It was measured from the point where it left the temporal bone plate to its tip. Styloid processes measuring more than 30 mm were considered elongated. Chi-squared and Fisher tests were used and the test is considered significant if the p-value is lower or equal to 0.05. Thirty-three per cent of the patients showed an elongated styloid process. Seventeen per cent were elongated on both right and left side, fifteen point nine per cent were elongated only in one side. The prevalence of elongated styloid process was high and a progressive increase of the elongation prevalence was found in older groups