Avaliação e características das quedas de pacientes durante a internação hospitalar

Objective: Evaluate and characterize the patients falls in a hospital in Southern Brazil. Method: Descriptive and retrospective study of 73 reports of falls in a hospital in Southern Brazil, from January 2016 to December 2019. Secondary data obtained by the institution's Patient Safety Center and the Morse Fall Scale were used, in a descriptive statistical analysis. Results: Most of the patients who suffered falls were male (60.3%), >61 years old (50.6%), clinical treatment (89.0%), patients with neoplasms (43.8%) in continuous medication use (91.8%). The falls occurred from their own same height (67.1%), in the bathroom (56.2%) and in the night shift (50.0%). In 50.7% of the falls there was damage to the patient, mild damage (62.2%), moderate damage (32.4%) and severe damage (5.4%). Conclusion: Improving the understanding of falls and their consequences can help health professionals in assessing risks and establishing preventive measures.Objetivo: Evaluar y caracterizar las caídas de pacientes en un hospital del sur de Brasil. Método: Estudio descriptivo y retrospectivo de 73 notificaciones de caídas en un hospital del sur de Brasil, de enero de 2016 a diciembre de 2019. Se utilizaron datos secundarios obtenidos por el Núcleo de Seguridad del Paciente de la institución y la Escala de Caídas Morse, con análisis estadístico descriptivo. Resultados: La mayoría de los pacientes que sufrieron caídas fueron hombres (60,3%), >61 años (50,6%), tratamiento clínico (89,0%), portadores de neoplasias (43,8%) en uso de medicación continua (91,8%). Las caídas ocurrieron desde la misma altura (67,1%), en el baño (56,2%) y en el turno de la noche (50,0%). En el 50,7% de las caídas hubo daño al paciente, considerados como: ligero (62,2%), moderado (32,4%) y grave (5,4%). Conclusión: Mejorar la comprensión de las caídas y sus consecuencias puede ayudar a los profesionales de la salud en la evaluación de los riesgos y en el establecimiento de medidas preventivas.Objetivo: Avaliar e caracterizar as quedas de pacientes em um hospital no sul do Brasil. Método: Estudo descritivo e retrospectivo de 73 notificações de quedas em um hospital no sul do Brasil, de janeiro 2016 a dezembro de 2019. Utilizou-se dados secundários obtidos pelo Núcleo de Segurança do Paciente da instituição e da Morse Fall Scale, sendo a análise estatística descritiva. Resultados: A maioria dos pacientes que sofreram quedas foi do sexo masculino (60,3%), >61 anos (50,6%), tratamento clínico (89,0%), portadores de neoplasias (43,8%) em uso contínuo de medicações (91,8%). As quedas ocorreram da própria altura (67,1%), no banheiro (56,2%) e no turno da noite (50,0%). Em 50,7% das quedas houve danos ao paciente, sendo os danos considerados como: leve (62,2%), moderado (32,4%) e grave (5,4%). Conclusão: Melhorar a compreensão das quedas e as suas consequências pode auxiliar os profissionais na avaliação dos riscos e no estabelecimento de medidas preventivas

Early motor development: risk factors for delay in a population study in Southern Brazil

OBJECTIVE: To assess risk factors associated with motor development delay at three months of age. METHODS: Cross-sectional study with mothers and their three-month-old babies in Southern Brazil. The Bayley-III Scale of Infant and Toddler Development (BSID-III) and the Alberta Infant Motor Scale (AIMS) were used to assess motor development. RESULTS: We evaluated 756 mothers and their three-month-old babies. The overall mean motor development assessed by the BSID-III and the AIMS was 104.7 (SD 13.5) and 55.4 (SD 25.4), respectively. When assessed by the BSID-III, the lowest motor development scores were among babies born by cesarean delivery (p = 0.002), prematurely (p < 0.001), and with low birth weight (p < 0.001). When assessed by the AIMS, babies born prematurely (p = 0.002) and with low birth weight (p=0.004) had the lowest motor development means. After a cluster analysis, we found that babies born by cesarean delivery, with low birth weight, and prematurely had more impaired motor development compared with children born without any risk factors. CONCLUSION: Identifying risk factors allows the implementation of early interventions to prevent motor development delay and, therefore, reduce the probability of other future problems

Can glutathione be a biomarker for suicide risk in women 18 months postpartum?

Background: Suicide risk is prominent among the problems affecting populations, mainly due to the broad family, psychosocial and economic impact. Most individuals at suicidal risk have some mental disorder. There is considerable evidence that psychiatric disorders are accompanied by the activation of neuro-immune and neuro-oxidative pathways. The aim of the study is to evaluate the serum levels of oxidative stress biomarkers in women at risk of suicide after 18 months of postpartum. Methods: This is a case-control study, nested within a cohort study. From this cohort, 45 women [15 without mood disorders and 30 with mood disorders (Major depression and Bipolar disorder)] were selected at 18 months postpartum, the depression and suicide risk were assessed using the MiniInternational Neuropsychiatric Interview Plus (MINI-Plus) instrument, module A and C, respectively. Blood was collected and stored for later analysis of the reactive species (DCFH), superoxide dismutase (SOD), and glutathione reduced (GSH). For data analysis, the SPSS program was used. To compare the nominal covariates with the outcome GSH levels, the Student’s t-test or analysis of variance (ANOVA) was used. Spearman’s correlation was performed for analysis between the quantitative covariates and the outcome. To analyze the interaction between the factors, multiple linear regression was performed. Bonferroni analysis was used as an additional/secondary result to visualize differences in glutathione levels according to risk severity. After the adjusted analysis, p-values < 0.05 were considered statistically significant. Results: The percentage of suicide risk observed in our sample of women at 18 months postpartum was 24.4% (n = 11). After adjusting for the independent variables, only the presence of suicide risk remained associated with the outcome (β = 0.173; p = 0.007), low levels of GSH at 18 months after postpartum. Likewise, we verified the difference in GSH levels according to the degree of suicide risk, observing a significant association between the differences in glutathione means in the group of women with moderate to high risk compared to the reference group (no suicide risk) (p = 0.009). Conclusion: Our findings suggest that GSH may be a potential biomarker or etiologic factor in women at moderate to high risk of suicide

Maternal-Fetal Attachment and Social-Emotional Development in Infants at 3 Months of Age: A Population-Based Study in Southern Brazil

Studies relate Maternal-Fetal Attachment (MFA) to delays in child development, however, the relationship with the social-emotional development is still unclear. Thus, the aim of this study was to investigate the association between MFA and social-emotional development in infants at 3 months old, in a population-based sample in southern Brazil. This was a follow-up study corresponding to second and third wave of a population-based cohort study with pregnant women who were living in Pelotas (Southern Brazil). Social-emotional development was assessed using the Bayley Scales of Infant Development - Third Edition (BSID-III) and MFA was measured with the Maternal-Fetal Attachment Scale (MFAS). The sample consisted of 702 mother-infant dyads. In the adjusted analysis, MFA was a predictor of social-emotional development, even when controlled for sociodemographic, maternal mental health and infant characteristics. Thus, with each increase to one point in the MFA score, there was an increase of β = 0.14, 95% CI [0.05, 0.23] in the social-emotional development score. These findings highlight the importance of MFA in early child development. Thus, infants with positive experiences of affection since the gestational period will be able to develop positive social and emotional health

Major depressive disorder during teenage pregnancy: socio-demographic, obstetric and psychosocial correlates

OBJECTIVES: To describe the prevalence of Major Depressive Disorder (MDD) during pregnancy in teenage mothers and to assess its association with socio-demographic characteristics, obstetric history and psychosocial variables. METHODS: A cross-sectional study was conducted with a sample of pregnant teenagers enrolled in the national public health system in the urban area of Pelotas, southern Brazil. MDD was assessed with the Mini International Neuropsychiatric Interview, the Abuse Assessment Screen was used to identify physical abuse within the last 12 months and during pregnancy, and social support was assessed with the Medical Outcomes Survey Social Support Scale. RESULTS: Forty-three (4.94%) potential subjects refused to participate, resulting in 828 total participants. The prevalence of MDD was 17.8%, 9.2% reported they had been subjected to violence within the last 12 months, while 5.8% had suffered violence during pregnancy, and the mean (SD) overall social support score was 87.40 (11.75). After adjustment, we found the highest incidence of MDD in adolescents with less than 8 years of education, followed by those with previous episodes of MDD and those with lower overall social support. CONCLUSIONS: MDD is a relatively common condition in pregnant teenagers and appears to be more prevalent in young mothers who are both socioeconomically and psychosocially underprivileged