7 research outputs found
Can the quality of colonic surgery be improved by standardisation of surgical technique with complete mesorectal excision?
No full textNon-Microradical Resection Margin as a Predictor of Recurrence In Stage III Colon Cancer Patients Undergoing Complete Mesocolic Excision:A Prospective Cohort Study
No full textDisease-free survival after complete mesocolic excision compared with conventional colon cancer surgery:a retrospective, population-based study
No full text5-year outcome after complete mesocolic excision for right-sided colon cancer:a population-based cohort study
No full textImmunopathology of in situ seminoma
No full textIn this study of the seminomatous human testis the composition, activity and apoptosis of lymphocytes infiltrating the immune-privileged seminiferous tubules with in situ seminoma were studied by immunohistochemistry and DNA fragmentation detection. Likewise the lymphocytes infiltrating the invasive seminomas were studied. The study showed equal numbers of CD4+ and CD8+ T cells and B cells, about 30% of the cells. Very few T γ/δ and NK cells were present. The activity in terms of IL-2-R, FasL and perforin expression was low. Apoptosis of the lymphocytic cells was limited. No differences were observed between the lymphocytes in seminiferous tubules with in situ seminoma and the lymphocytes in invasive tumours. The study suggests that either specifically committed lymphocytes are not present or, if present, immune-suppressing mechanisms in addition to FasL may be working
