Sermon : predicado en la santa iglesia catedral de Malaga el dia 19 de agosto de 1893, aniversario de la Reconquista de dicha ciudad ...

Copia digital. realizada por la Biblioteca de Andalucí

La Catedral de Malaga [manuscrito]

Copia digital : Diputación de Málaga. Biblioteca Canovas del Castillo, 201

Al Ilustrissimo, y Supremo Tribunal de los Señores Iudicantes por la parte que denuncia en el processo de la Excelentissima Señora Marquesa de Cerrablo, y Excelentissimo Conde de Aranda.: Illmo Señor. La introduccion de este Tribunal Grande de V. S. I. costô mucho a este Reyno ... pues no lo pudo conseguir en unas Cortes, repitiendo las instancias en las siguientes, hasta que se consiguiô, como dizen nuestros historiadores ...

Precede al texto en p.1: "Iesus, Maria, Iosef"Copia digital : Diputación Provincial de Zaragoza. Servicio de Archivos y Bibliotecas, 2010Datos de tít. sacados de p.1, y mención de responsabilidad del final del textoSign.: A\p11\

Por los Ilustres SS. Dotores... Joseph Francisco Moles, y... Ivan Antonio Tena, y Bolea, Lugartenientes de la Corte del... Iusticia de Aragon. Respuesta al informe de... Fray Lorenço Galvan... en la denunciacion pendiente a su instancia en el Tribunal de los Ilustrissimos señores Iudicantes

Copia digital : Diputación Provincial de Zaragoza. Servicio de Archivos y Bibliotecas, 2010Precede al tít. "Iesus, Maria, Ioseph"Fecha tomada de p. 2 "Cargo primero que los señores lugartenientes inhibieron el processo de Aprehensionen... en los dias... del año 1681... y de 1682"[2] p. intercaladas entre las p. 12 y 13Sign.: A-B2, A, *2, D-E2Apostillas marginale

Real ordenanza adicional a la de reemplazos de tres de noviembre de mil setecientos y setenta, por la qual se sirve S.M. declarar varias esenciones y casos para la mas facil y exacta egecucion del alistamiento y sorteo, guardada equidad

Escut reial xil. a port. i caplletra ornada a l'inici del textLLoc i dta del text: " Dada en el pardo á diez y siete de Marzo de mil setecinetos setenta y tres" signat "el Conde de Ricla"Sign.: A10"Real Ordenanza adicional a la de reemplazos de tres de noviembre de mil setecientos y setenta, por la qual se sirve S.M. declarar varias esenciones y casos para la más fácil y exacta egecucion del alistamiento y sortéo, guardada equidad" --Catàleg manual de la Biblioteca Econòmica CarandellReial Ordenança addicional a la de remplaçaments del tres de novembre de mil set-cents seixanta, pel qual es serveix S.M. varies exempcions i casos per la més fàcil i exacta execució de l'allistament i sorteig, guardada l'equitat.

Comparison of Antibacterial Activity and Wound Healing in a Superficial Abrasion Mouse Model of Staphylococcus aureus Skin Infection Using Photodynamic Therapy Based on Methylene Blue or Mupirocin or Both

Background: Antibiotic resistance and impaired wound healing are major concerns in S. aureus superficial skin infections, and new therapies are needed. Antimicrobial photodynamic therapy (aPDT) is a new therapeutic approach for infections, but it also improves healing in many wound models. Objective: To compare the antimicrobial activity and the effects on wound healing of aPDT based on Methylene Blue (MB-aPDT) with mupirocin treatment, either alone or in combination, in superficial skin wounds of S. aureus-infected mice. Additionally, to evaluate the clinical, microbiological, and cosmetic effects on wound healing. Materials and Methods: A superficial skin infection model of S. aureus was established in SKH-1 mice. Infected wounds were treated with MB-aPDT, MB-aPDT with a daily topical mupirocin or only with mupirocin. No treatment was carried out in control animals. Daily clinical and microbiological examinations were performed until complete clinical wound healing. Histopathological studies and statistical analysis were performed at the end of the study. Results: MB-aPDT treatment induced the best wound healing compared to mupirocin alone or to mupirocin plus MB-aPDT. Superficial contraction at 24 h and a greater reduction in size at 48 h, quicker detachment of the crust, less scaling, and absence of scars were observed. Histopathological studies correlated with clinical and gross findings. By contrast, mupirocin showed the highest logaritmic reduction of S. aureus. Conclusions: MB-aPDT and mupirocin treatments are effective in a murine superficial skin infection model of S. aureus. One session of MB-aPDT was the best option for clinical wound healing and cosmetic results. The addition of mupirocin to MB-aPDT treatment improved antimicrobial activity; however, it did not enhance wound healing. No synergistic antibacterial effects were detected. © Copyright © 2021 Pérez, Robres, Moreno, Bolea, Verde, Pérez-Laguna, Aspiroz, Gilaberte and Rezusta

En la causa de denunciacion que pende a instancia de Fr. D. Lorenzo Lopez Galvan y Bayetola... contra... Ioseph Francisco Moles y... Iuan Antonio de Tena y Bolea... en el presente año 1682 por el denunciante

Copia digital : Diputación Provincial de Zaragoza. Servicio de Archivos y Bibliotecas, 2010Texto fechado "en Zaragoça 28. de Iunio de 1682

Ambrosio Funes de Villalpando, Abarca de Bolea, &c. Conde de Ricla, Señor de las Baronias del Valle de la Solana, y Murillo de Tou ... Por quanto hemos recibido una Pragmàtica-Sancion de su Magestad, su fecha en San Ildefonso á veinte de agosto proxîmo pasado, por la qual se declara tocar el conocimiento de las causas de falsificacion de moneda á las Justicias Ordinarias ...

Pragmática 17710820Sign.: [ ]2Título tomado del inicio del textoTexto con fecha de publicación en Barcelona el 5 de noviembre de 177

IP-10 Levels as an Accurate Screening Tool to Detect Acute HIV Infection in Resource-Limited Settings.

Acute HIV infection (AHI) is the period prior to seroconversion characterized by high viral replication, hyper-transmission potential and commonly, non-specific febrile illness. AHI detection requires HIV-RNA viral load (VL) determination, which has very limited access in low-income countries due to restrictive costs and implementation constraints. We sought to identify a biomarker that could enable AHI diagnosis in scarce-resource settings, and to evaluate the feasibility of its implementation. HIV-seronegative adults presenting at the Manhiça District Hospital, Mozambique, with reported-fever were tested for VL. Plasma levels of 49 inflammatory biomarkers from AHI (n = 61) and non-HIV infected outpatients (n = 65) were determined by Luminex and ELISA. IP-10 demonstrated the best predictive power for AHI detection (AUC = 0.88 [95%CI 0.80-0.96]). A cut-off value of IP-10 ≥ 161.6 pg/mL provided a sensitivity of 95.5% (95%CI 85.5-99.5) and a specificity of 76.5% (95%CI 62.5-87.2). The implementation of an IP-10 screening test could avert from 21 to 84 new infections and save from US$176,609 to US$533,467 to the health system per 1,000 tested patients. We conclude that IP-10 is an accurate biomarker to screen febrile HIV-seronegative individuals for subsequent AHI diagnosis with VL. Such an algorithm is a cost-effective strategy to prevent disease progression and a substantial number of further HIV infections