6,437 research outputs found
Experimental tests of solar collectors prototypes systems
Solar thermal collectors represent one of the most widely used technologies for heat production from renewable energy sources. To increase efficiency and to not increase too much cost different type of solar collectors, and in particular of evacuated tube collectors have been realized. In order to compare performance, tests at different conditions and in different configurations have to be performed. The aim of this paper is to establish the performance of a new prototype via an experimental evaluation of the performance in different conditions and configurations of three collectors. The prototype is particular owing to his new head configuration that permits an innovative parallel configuration way. Therefore, parallel and series configurations have been analyzed applying the UNI-EN 12975, in a steady-state regime. The efficiencies of the two configurations have been tested for different flow rates and different inflow water temperatures. The experimental results show that, with the same input flow rate to the single collector, the parallel configuration has higher performance than the series one, reaching 15% higher level of efficiency. Thus, it seems that these prototypes in optimized configuration can lead to a systems improvement, thereby increasing the overall energy production or giving the same energy production with smaller collector area. © 2015 Published by Elsevier Ltd
Pharmacogenetic labyrinth of neovascular age-related macular degeneration therapy: how to escape and move forward?
Heterogeneous reconstruction of tracks and primary vertices with the CMS pixel tracker
The High-Luminosity upgrade of the LHC will see the accelerator reach an
instantaneous luminosity of with an average
pileup of proton-proton collisions. These conditions will pose an
unprecedented challenge to the online and offline reconstruction software
developed by the experiments. The computational complexity will exceed by far
the expected increase in processing power for conventional CPUs, demanding an
alternative approach. Industry and High-Performance Computing (HPC) centres are
successfully using heterogeneous computing platforms to achieve higher
throughput and better energy efficiency by matching each job to the most
appropriate architecture. In this paper we will describe the results of a
heterogeneous implementation of pixel tracks and vertices reconstruction chain
on Graphics Processing Units (GPUs). The framework has been designed and
developed to be integrated in the CMS reconstruction software, CMSSW. The speed
up achieved by leveraging GPUs allows for more complex algorithms to be
executed, obtaining better physics output and a higher throughput
Iatrogenic Rhabdomyolisis and Guillain-Barre’ Syndrome: a Dangerous Association.
Guillan-Barré Syndrome (GBS) is an acute, symmetrical polyneuropathy with a clinical manifestation of flaccid
paralysis with areflexia and variable sensory disturbance. GBS has an incidence of 1-2 cases/100.000 inhabitants
for year. The pathological spectrum of GBS includes Acute Inflammatory Demyelinating Polyneuropathy (AIDP),
Acute Motor Axonal Neuropathy (AMAN) and Acute Motor Sensory Axonal Neuropathy (AMSAN). We report a case
of an 81-year-old man with GBS (subtype AMSAN), secondary to a previous Micoplasma Pneumoniae infection, who
presented with an elevation of Creatin Kinase (CK) serum levels, and worsened by a co-administration of statins
and clarithromycin. By our knowledge there are few cases in the literature in which the association of these drugs
contributed to worsening GBS
Unilateral Application of Cathodal tDCS Reduces Transcallosal Inhibition and Improves Visual Acuity in Amblyopic Patients
Objective: Amblyopia is a neurodevelopmental disorder characterized by visual acuity and contrast sensitivity loss, refractory to pharmacological and optical treatments in adulthood. In animals, the corpus callosum (CC) contributes to suppression of visual responses of the amblyopic eye. To investigate the role of interhemispheric pathways in amblyopic patients, we studied the response of the visual cortex to transcranial Direct Current Stimulation (tDCS) applied over the primary visual area (V1) contralateral to the "lazy eye." Methods: Visual acuity (logMAR) was assessed before (T0), immediately after (T1) and 60' following the application of cathodal tDCS (2.0 mA, 20') in 12 amblyopic patients. At each time point, Visual Evoked Potentials (VEPs) triggered by grating stimuli of different contrasts (K90%, K20%) were recorded in both hemispheres and compared to those obtained in healthy volunteers. Results: Cathodal tDCS improved visual acuity respect to baseline (p < 0.0001), whereas sham polarization had no significant effect. At T1, tDCS induced an inhibitory effect on VEPs amplitudes at all contrasts in the targeted side and a facilitation of responses in the hemisphere ipsilateral to the amblyopic eye; compared with controls, the facilitation persisted at T2 for high contrasts (K90%; Holm-Sidak post hoc method, p < 0.001), while the stimulated hemisphere recovered more quickly from inhibition (Holm-Sidak post hoc method, p < 0.001). Conclusions: tDCS is a promising treatment for amblyopia in adults. The rapid recovery of excitability and the concurrent transcallosal disinhibition following perturbation of cortical activity may support a critical role of interhemispheric balance in the pathophysiology of amblyopia
Peri-lead edema and local field potential correlation in post-surgery subthalamic nucleus deep brain stimulation patients
Implanting deep brain stimulation (DBS) electrodes in patients with Parkinson's disease often results in the appearance of a non-infectious, delayed-onset edema that disappears over time. However, the time window between the DBS electrode and DBS stimulating device implant is often used to record local field potentials (LFPs) which are used both to better understand basal ganglia pathophysiology and to improve DBS therapy. In this work, we investigated whether the presence of post-surgery edema correlates with the quality of LFP recordings in eight patients with advanced Parkinson's disease implanted with subthalamic DBS electrodes. The magnetic resonance scans of the brain after 8.5 +/- 1.5 days from the implantation surgery were segmented and the peri-electrode edema volume was calculated for both brain hemispheres. We found a correlation (rho = -0.81, p < 0.0218, Spearman's correlation coefficient) between left side local field potentials of the low beta band (11-20 Hz) and the edema volume of the same side. No other significant differences between the hemispheres were found. Despite the limited sample size, our results suggest that the effect on LFPs may be related to the edema localization, thus indicating a mechanism involving brain networks instead of a simple change in the electrode-tissue interface
- …