222 research outputs found
I-Brane Inflow and Anomalous Couplings on D-Branes
We show that the anomalous couplings of -brane gauge and gravitational
fields to Ramond-Ramond tensor potentials can be deduced by a simple anomaly
inflow argument applied to intersecting -branes and use this to determine
the eight-form gravitational coupling.Comment: 8 pages, harvmac, no figure
Two-Flavor Staggered Fermion Thermodynamics at N_t = 12
We present results of an ongoing study of the nature of the high temperature
crossover in QCD with two light fermion flavors. These results are obtained
with the conventional staggered fermion action at the smallest lattice spacing
to date---approximately 0.1 fm. Of particular interest are a study of the
temperature of the crossover a determination of the induced baryon charge and
baryon susceptibility, the scalar susceptibility, and the chiral order
parameter, used to test models of critical behavior associated with chiral
symmetry restoration. From our new data and published results for N_t = 4, 6,
and 8, we determine the QCD magnetic equation of state from the chiral order
parameter using O(4) and mean field critical exponents and compare it with the
corresponding equation of state obtained from an O(4) spin model and mean field
theory. We also present a scaling analysis of the Polyakov loop, suggesting a
temperature dependent ``constituent quark free energy.''Comment: LaTeX 25 pages, 15 Postscript figure
On the Open-Closed B-Model
We study the coupling of the closed string to the open string in the
topological B-model. These couplings can be viewed as gauge invariant
observables in the open string field theory, or as deformations of the
differential graded algebra describing the OSFT. This is interpreted as an
intertwining map from the closed string sector to the deformation (Hochschild)
complex of the open string algebra. By an explicit calculation we show that
this map induces an isomorphism of Gerstenhaber algebras on the level of
cohomology. Reversely, this can be used to derive the closed string from the
open string. We shortly comment on generalizations to other models, such as the
A-model.Comment: LaTeX, 48 pages. Citation adde
Effect of thyroid hormone therapy on fatigability in older adults with subclinical hypothyroidism: a nested study within a randomized placebo-controlled trial
Background:
Fatigue often triggers screening for and treatment of subclinical hypothyroidism. However, data on the impact of levothyroxine on fatigue is limited and previous studies might not have captured all aspects of fatigue.
Method:
This study is nested within the randomized, placebo-controlled, multicenter TRUST trial, including community-dwelling participants aged â„65 and older, with persistent subclinical hypothyroidism (TSH 4.60â19.99 mIU/L, normal free thyroxine levels) from Switzerland and Ireland. Interventions consisted of daily levothyroxine starting with 50 ÎŒg (25 ÎŒg if weight <50 kg or known coronary heart diseases) together with dose adjustments to achieve a normal TSH and mock titration in the placebo group. Main outcome was the change in physical and mental fatigability using the Pittsburgh Fatigability Scale over 1 year, assessed through multivariable linear regression with adjustment for country, sex, and levothyroxine starting dose.
Results:
Among 230 participants, the mean ± standard deviation (SD) TSH was 6.2 ± 1.9 mIU/L at baseline and decreased to 3.1 ± 1.3 with LT4 (n = 119) versus 5.3 ± 2.3 with placebo (n = 111, p < .001) after 1 year. After adjustment we found no between-group difference at 1 year on perceived physical (0.2; 95% CI â1.8 to 2.1; p = .88), or mental fatigability (â1.0; 95% CI â2.8 to 0.8; p = .26). In participants with higher fatigability at baseline (â„15 points for the physical score [n = 88] or â„13 points for the mental score [n = 41]), the adjusted between-group differences at 1 year were 0.4 (95% CI â3.6 to 2.8, p = .79) and â2.2 (95% CI â8.8 to 4.5, p = .51).
Conclusions:
Levothyroxine in older adults with mild subclinical hypothyroidism provides no change in physical or mental fatigability
Spitzer Survey of the Large Magellanic Cloud, Surveying the Agents of a Galaxy's Evolution (SAGE) I: Overview and Initial Results
We are performing a uniform and unbiased, ~7x7 degrees imaging survey of the
Large Magellanic Cloud (LMC), using the IRAC and MIPS instruments on board the
Spitzer Space Telescope in order to survey the agents of a galaxy's evolution
(SAGE), the interstellar medium (ISM) and stars in the LMC. The detection of
diffuse ISM with column densities >1.2x10^21 H cm^-2 permits detailed studies
of dust processes in the ISM. SAGE's point source sensitivity enables a
complete census of newly formed stars with masses >3 solar masses that will
determine the current star formation rate in the LMC. SAGE's detection of
evolved stars with mass loss rates >1x10^-8 solar masses per year will quantify
the rate at which evolved stars inject mass into the ISM of the LMC. The
observing strategy includes two epochs in 2005, separated by three months, that
both mitigate instrumental artifacts and constrain source variability. The SAGE
data are non-proprietary. The data processing includes IRAC and MIPS pipelines
and a database for mining the point source catalogs, which will be released to
the community in support of Spitzer proposal cycles 4 and 5. We present initial
results on the epoch 1 data with a special focus on the N79 and N83 region. The
SAGE epoch 1 point source catalog has ~4 million sources. The point source
counts are highest for the IRAC 3.6 microns band and decrease dramatically
towards longer wavelengths consistent with the fact that stars dominate the
point source catalogs and that the dusty objects, e.g. young stellar objects
and dusty evolved stars that detected at the longer wavelengths, are rare in
comparison. We outline a strategy for identifying foreground MW stars, that may
comprise as much as 18% of the source list, and background galaxies, that may
comprise ~12% of the source list.Comment: Accepted by the Astronomical Journa
Spitzer survey of the Large Magellanic Cloud, surveying the agents of a galaxy's evolution (SAGE). IV. Dust properties in the interstellar medium
The goal of this paper is to present the results of a preliminary analysis of the extended infrared (IR) emission by dust in the interstellar medium (ISM) of the Large Magellanic Cloud (LMC). We combine Spitzer Surveying the Agents of Galaxy Evolution (SAGE) and Infrared Astronomical Satellite (IRAS) data and correlate the infrared emission with gas tracers of H I, CO, and Hα. We present a global analysis of the infrared emission as well as detailed modeling of the spectral energy distribution (SED) of a few selected regions. Extended emission by dust associated with the neutral, molecular, and diffuse ionized phases of the ISM is detected at all IR bands from 3.6 ÎŒm to 160 ÎŒm. The relative abundance of the various dust species appears quite similar to that in the Milky Way (MW) in all the regions we have modeled. We construct maps of the temperature of large dust grains. The temperature map shows variations in the range 12.1-34.7 K, with a systematic gradient from the inner to outer regions, tracing the general distribution of massive stars and individual H II regions as well as showing warmer dust in the stellar bar. This map is used to derive the far-infrared (FIR) optical depth of large dust grains. We find two main departures in the LMC with respect to expectations based on the MW: (1) excess mid-infrared (MIR) emission near 70 ÎŒm, referred to as the 70 ÎŒm excess, and (2) departures from linear correlation between the FIR optical depth and the gas column density, which we refer to as FIR excess emission. The 70 ÎŒm excess increases gradually from the MW to the LMC to the Small Magellanic Cloud (SMC), suggesting evolution with decreasing metallicity. The excess is associated with the neutral and diffuse ionized gas, with the strongest excess region located in a loop structure next to 30 Dor. We show that the 70 ÎŒm excess can be explained by a modification of the size distribution of very small grains with respect to that in the MW, and a corresponding mass increase of â13% of the total dust mass in selected regions. The most likely explanation is that the 70 ÎŒm excess is due to the production of large very small grains (VSG) through erosion of larger grains in the diffuse medium. This FIR excess could be due to intrinsic variations of the dust/gas ratio, which would then vary from 4.6 to 2.3 times lower than the MW values across the LMC, but X_(CO) values derived from the IR emission would then be about three times lower than those derived from the Virial analysis of the CO data. We also investigate the possibility that the FIR excess is associated with an additional gas component undetected in the available gas tracers. Assuming a constant dust abundance in all ISM phases, the additional gas component would have twice the known H I mass. We show that it is plausible that the FIR excess is due to cold atomic gas that is optically thick in the 21 cm line, while the contribution by a pure H_2 phase with no CO emission remains a possible explanation
Orientifolds of K3 and Calabi-Yau Manifolds with Intersecting D-branes
We investigate orientifolds of type II string theory on K3 and Calabi-Yau
3-folds with intersecting D-branes wrapping special Lagrangian cycles. We
determine quite generically the chiral massless spectrum in terms of
topological invariants and discuss both orbifold examples and algebraic
realizations in detail. Intriguingly, the developed techniques provide an
elegant way to figure out the chiral sector of orientifold models without
computing any explicit string partition function. As a new example we derive a
non-supersymmetric Standard-like Model from an orientifold of type IIA on the
quintic Calabi-Yau 3-fold with wrapped D6-branes. In the case of supersymmetric
intersecting brane models on Calabi-Yau manifolds we discuss the D-term and
F-term potentials, the effective gauge couplings and the Green-Schwarz
mechanism. The mirror symmetric formulation of this construction is provided
within type IIB theory. We finally include a short discussion about the lift of
these models from type IIB on K3 to F-theory and from type IIA on Calabi-Yau
3-folds to M-theory on G_2 manifolds.Comment: 82 pages, harvmac, 5 figures. v2: references added. v3: T^6
orientifold corrected, JHEP versio
Circumstellar discs: What will be next?
This prospective chapter gives our view on the evolution of the study of
circumstellar discs within the next 20 years from both observational and
theoretical sides. We first present the expected improvements in our knowledge
of protoplanetary discs as for their masses, sizes, chemistry, the presence of
planets as well as the evolutionary processes shaping these discs. We then
explore the older debris disc stage and explain what will be learnt concerning
their birth, the intrinsic links between these discs and planets, the hot dust
and the gas detected around main sequence stars as well as discs around white
dwarfs.Comment: invited review; comments welcome (32 pages
Stable isotope food-web analysis and mercury biomagnification in polar bears ( Ursus maritimus )
Mercury (Hg) biomagnification occurs in many ecosystems, resulting in a greater potential for toxicological effects in higher-level trophic feeders. However, Hg transport pathways through different food-web channels are not well known, particularly in high-latitude systems affected by the atmospheric Hg deposition associated with snow and ice. Here, we report on stable carbon and nitrogen isotope ratios, and Hg concentrations, determined for 26, late 19th and early 20th century, polar bear ( Ursus maritimus ) hair specimens, collected from catalogued museum collections. These data elucidate relationships between the high-latitude marine food-web structure and Hg concentrations in polar bears. The carbon isotope compositions of polar bear hairs suggest that polar bears derive nutrition from coupled food-web channels, based in pelagic and sympagic primary producers, whereas the nitrogen isotope compositions indicate that polar bears occupy > fourth-level trophic positions. Our results show a positive correlation between polar bear hair Hg concentrations and ÎŽ 15 N. Interpretation of the stable isotope data in combination with Hg concentrations tentatively suggests that polar bears participating in predominantly pelagic food webs exhibit higher mercury concentrations than polar bears participating in predominantly sympagic food webs.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73930/1/j.1751-8369.2009.00114.x.pd
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