Whole genome analysis of a schistosomiasis-transmitting freshwater snail

Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis

Laser Doppler Interferometer based on a solid Fabry-Perot Etalon for measurement of surface velocity in shock experiments

WOSInternational audienceThis study presents an original optical system designed for measuring the free surface velocity for shock wave diagnostics. The system is based on a solid Fabry–Perot etalon interferometer coupled to a tunable, single frequency laser. The setup assembled for this purpose can measure velocities up to 200 m s−1 and has a resolution time of about 1 ns. This system was validated in shock experiments performed on thin aluminum samples. The shock waves were generated by a pulsed laser on a water confinement configuration and the surface velocity was measured on the opposite side of the sample. The signals obtained are in good agreement with numerical simulation and results found in the literature. This system presents an interesting alternative to the velocity interferometer system for any reflectors (VISAR) commonly used in shock experiments

Recent developments of the laser ultrasonic technology and of its applications

Peer reviewed: YesNRC publication: Ye

High frequency ultrasound generation using a femtosecond laser

We present measurements of high frequency ultrasound generated by a femtosecond laser pulse. Focussed on thin aluminum foils (8 - 80 mum), the measured ultrasonic spectrum extends up to a detection limit of 800 MHz. The high frequency ultrasonic echoes allow measurements of foil thickness down to 8 mum, the minimum foil thickness used in this set of experiments.Peer reviewed: YesNRC publication: Ye

Laser Shock Adhesion Test (LASAT) of composite materials for aerospace industry

International audienc