How Far Can I Trust You? The Impact of Distance and Cultural Values on Leaders’ Trustworthiness

Employees\u27 level of trust in leaders has long been deemed an important key to successful organizational dynamics and performance. Utilizing survey data, the current study investigates differences in levels of trust between one\u27s immediate manager and the organization\u27s top leadership, the impact of individualism/collectivism on these levels of trust, and the influence of leader-follower distance on leadership trust. Results revealed higher levels of trust for direct leaders than organizational leaders among the U.S. sample. While individualism/collectivism was not found to significantly affect levels of leadership trust, perceptions of less leadership distance had a positive impact on levels of leadership trust

When a leader job resource can be ambivalent or even destructive: Independence at work as a double-edged sword

<div><p>Independence at work is commonly considered a job resource which fosters motivation and employee well-being. Somewhat paradoxically, it is embedded in a relationship, and employees’ independence also hinges on their leaders’ willingness to grant it. Analyzing this resource as part of the leader-follower relationship can be useful in exploring its beneficial, ambivalent, or detrimental reciprocal effects. We present two Actor-Partner Interdependence Models (APIM) which analyze leaders’ and followers’ independence as antecedents, and work engagement and emotional exhaustion as outcomes. We test our models on 112 pairs of UK workers, finding a significant partner effect between leaders’ independence and followers’ exhaustion. Our findings confirm the utility of a dyadic perspective for investigating leadership and well-being at work, and suggest improvements for leadership training and measures fostering job well-being.</p></div

Theranostic Fibers for Simultaneous Imaging and Drug Delivery

New methods for creating theranostic systems with simultaneous encapsulation of therapeutic, diagnostic, and targeting agents are much sought after. This work reports for the first time the use of coaxial electrospinning to prepare such systems in the form of core–shell fibers. Eudragit S100 was used to form the shell of the fibers, while the core comprised poly(ethylene oxide) loaded with the magnetic resonance contrast agent Gd(DTPA) (Gd(III) diethylenetriaminepentaacetate hydrate) and indomethacin as a model therapeutic agent. The fibers had linear cylindrical morphologies with clear core–shell structures, as demonstrated by electron microscopy. X-ray diffraction and differential scanning calorimetry proved that both indomethacin and Gd(DTPA) were present in the fibers in the amorphous physical form. This is thought to be a result of intermolecular interactions between the different components, the presence of which was suggested by infrared spectroscopy. In vitro dissolution tests indicated that the fibers could provide targeted release of the active ingredients through a combined mechanism of erosion and diffusion. The proton relaxivities for Gd(DTPA) released from the fibers into tris buffer increased (r1 = 4.79–9.75 s–1 mM–1; r2 = 7.98–14.22 s–1 mM–1) compared with fresh Gd(DTPA) (r1 = 4.13 s–1 mM–1 and r2 = 4.40 s–1 mM–1), which proved that electrospinning has not diminished the contrast properties of the complex. The new systems reported herein thus offer a new platform for delivering therapeutic and imaging agents simultaneously to the colon

An inquiry-based learning approach to teaching information retrieval

The study of information retrieval (IR) has increased in interest and importance with the explosive growth of online information in recent years. Learning about IR within formal courses of study enables users of search engines to use them more knowledgeably and effectively, while providing the starting point for the explorations of new researchers into novel search technologies. Although IR can be taught in a traditional manner of formal classroom instruction with students being led through the details of the subject and expected to reproduce this in assessment, the nature of IR as a topic makes it an ideal subject for inquiry-based learning approaches to teaching. In an inquiry-based learning approach students are introduced to the principles of a subject and then encouraged to develop their understanding by solving structured or open problems. Working through solutions in subsequent class discussions enables students to appreciate the availability of alternative solutions as proposed by their classmates. Following this approach students not only learn the details of IR techniques, but significantly, naturally learn to apply them in solution of problems. In doing this they not only gain an appreciation of alternative solutions to a problem, but also how to assess their relative strengths and weaknesses. Developing confidence and skills in problem solving enables student assessment to be structured around solution of problems. Thus students can be assessed on the basis of their understanding and ability to apply techniques, rather simply their skill at reciting facts. This has the additional benefit of encouraging general problem solving skills which can be of benefit in other subjects. This approach to teaching IR was successfully implemented in an undergraduate module where students were assessed in a written examination exploring their knowledge and understanding of the principles of IR and their ability to apply them to solving problems, and a written assignment based on developing an individual research proposal

Higher biomass accumulation by increasing phosphoribosylpyrophosphate synthetase activity in Arabidopsis thaliana and Nicotiana tabacum

Plants are able to produce all the organic compounds required for development and growth. As developmental processes and metabolic pathways use a common resource pool, the tight regulation of the distribution of metabolites between growth, production of defence compounds and storage products can be assumed. A transgenic approach was used to investigate the importance of supplying the key intermediate phosphoribosylpyrophosphate (PRPP) for plant growth and biomass accumulation in the model plant Arabidopsis thaliana and in Nicotiana tabacum. For this purpose, the Ashbya gossypii genes coding for either PRPP synthetase (PRS) or a mutated variant of the same gene were over-expressed under the control of a constitutive promoter. It was shown that increased PRS activity in A. thaliana or N. tabacum leads to a substantial increase in biomass accumulation under different standardized growth conditions. Growth enhancement was accompanied by significant changes in the amount of sugars and other metabolites. This study provides evidence that the supply of PRPP co-limits growth rates, and has obvious implications for biotechnological strategies aiming to increase plant biomass as an alternative renewable energy source

Leadership in “Confucian Asia”: a three-country study of justice, trust, and transformational leadership

Increasing globalization and the economic uncertainty inherent in the recent financial crisis have strained the already tenuous commitment of many employees, making followers’ perceptions of justice and trust more critical now than ever before in retaining a loyal workforce. A model of leadership, organizational justice, trust, and work outcomes such as commitment and satisfaction, similar to the one tested in the US, was extended to three countries in the so-called “Confucian Asian Cluster” in the Global Leadership and Organizational Behavior Effectiveness (GLOBE) study. Data were collected from executives in: Mainland China (N¼131), Singapore (N¼246), and Taiwan (N¼99). Results indicate that transformational leaders in the Mainland build trust through procedural justice and distributive justice; trust in the leader is, in turn, related to job satisfaction and commitment. Transformational leaders in Singapore work indirectly through both distributive and procedural justice mechanisms to build trust and work outcomes, and also directly through trust to influence satisfaction and commitment. Finally, leaders in Taiwan use transformational leadership to influence procedural justice, trust, commitment, and satisfaction. Implications are discussed for leaders attempting to foster committed and satisfied workers in light of challenging economic circumstances

Underwater Spectroscopic Techniques for In-situ Nuclear Waste Characterisation

Decommissioning legacy spent fuel ponds within nuclear facilities can be a complicated process, largely in part due to the unknown state of materials deposited into such storage ponds during the operational lifetime of the facility. Materials may have corroded, and their condition deteriorated. Due to the nature of the materials deposited in such storage sites, minimising disturbance is desirable, and as such non-destructive techniques such as optical analysis methods are preferred over destructive techniques. In this work, we demonstrate three such optical techniques (Raman spectroscopy, photogrammetry, and hyperspectral imaging) capable of ascertaining useful characteristics of objects such as material type, surface corrosion, degradation, and 3D structure. A pool environment was used to capture data and demonstrate the techniques suitability for use in nuclear waste characterization in active spent fuel ponds. The optical techniques used enabled material characteristics to be obtained

Electrospun pH-sensitive core-shell polymer nanocomposites fabricated using a tri-axial process

A modified tri-axial electrospinning process was developed for the generation of a new type of pH-sensitive polymer/lipid nanocomposite. The systems produced are able to promote both dissolution and permeation of a model poorly water-soluble drug. First, we show that it is possible to run a tri-axial procress with only one of the three fluids being electrospinnable. Using an electrospinnable middle fluid of Eudragit S100 (ES100) with pure ethanol as the outer solvent and an unspinnable lecithin-diclofenac sodium (PL-DS) core solution, nanofibers with linear morphology and clear core/shell structures can be fabricated continuously and smoothly. X-ray diffraction proved that these nanofibers are structural nanocomposites with the drug present in an amorphous state. In vitro dissolution tests demonstrated that the formulations could preclude release in acidic conditions, and that the drug was released from the fibers in two successive steps at neutral pH. The first step is the dissolution of the shell ES100 and the conversion of the core PL-DS into sub-micron sized particles. This frees some DS into solution, and later the remaining DS is gradually released from the PL-DS particles through diffusion. Ex vivo permeation results showed that the composite nanofibers give a more than two-fold uplift in the amount of DS passing through the colonic membrane as compared to pure DS; 74% of the transmitted drug was in the form of PL-DS particles. The new tri-axial electrospinning process developed in this work provides a platform to fabricate structural nanomaterials, and the core-shell polymer-PL nanocomposites we have produced have significant potential applications for oral colon-targeted drug delivery. STATEMENT OF SIGNIFICANCE: A modified tri-axial electrospinning is demonstrated to create a new type of core-shell pH-sensitive polymer/lipid nanocomposites, in which an electrospinnable middle fluid is exploited to support the un-spinnable outer and inner fluids. The structural nanocomposites are able to provide a colon-targeted sustained release and an enhanced permeation performance of diclofenac sodium. The developed tri-axial process can provide a platform for fabricating new structural nanomaterials with high quality. The strategy of a combined usage of polymeric excipients and phosphilipid in a core-shell format should provide new possibilities of developing novel drug delivery systems for efficacious oral administration of poorly-water soluble drugs

Charismatic and Affective Rhetoric in a Presidential Campaign

Although prior research demonstrates that charisma and rhetoric are two determinants of voting behavior, few studies have examined the effects of charismatic rhetoric and affect as they pertain to the outcomes of presidential elections. Using DICTION software for content analysis, 432 pre-convention speeches from the 2008 presidential election were analyzed to explore the effects that charismatic rhetoric and affect have on presidential candidates’ success. Results indicate that there were more similarities than differences in the charismatic and affect-laden rhetoric of successful and unsuccessful presidential candidates in both the Republican and Democratic parties. Overall, the results demonstrate that both successful and unsuccessful presidential candidates used charismatic rhetoric and emotional language to motivate their followers in the 2008 presidential election