581 research outputs found
Interaction of reed and acoustic resonator in clarinetlike systems
Sound emergence in clarinetlike instruments is investigated in terms of
instability of the static regime. Various models of reed-bore coupling are
considered, from the pioneering work of Wilson and Beavers ["Operating modes of
the clarinet", J. Acoust. Soc. Am. 56, 653--658 (1974)] to more recent modeling
including viscothermal bore losses and vena contracta at the reed inlet. The
pressure threshold above which these models may oscillate as well as the
frequency of oscillation at threshold are calculated. In addition to Wilson and
Beavers' previous conclusions concerning the role of the reed damping in the
selection of the register the instrument will play on, the influence of the
reed motion induced flow is also emphasized, particularly its effect on playing
frequencies, contributing to reduce discrepancies between Wilson and Beavers'
experimental results and theory, despite discrepancies still remain concerning
the pressure threshold. Finally, analytical approximations of the oscillating
solution based on Fourier series expansion are obtained in the vicinity of the
threshold of oscillation. This allows to emphasize the conditions which
determine the nature of the bifurcation (direct or inverse) through which the
note may emerge, with therefore important consequences on the musical playing
performances
Thermal noise in interferometric gravitational wave detectors due to dielectric optical coatings
We report on thermal noise from the internal friction of dielectric coatings
made from alternating layers of Ta2O5 and SiO2 deposited on fused silica
substrates. We present calculations of the thermal noise in gravitational wave
interferometers due to optical coatings, when the material properties of the
coating are different from those of the substrate and the mechanical loss angle
in the coating is anisotropic. The loss angle in the coatings for strains
parallel to the substrate surface was determined from ringdown experiments. We
measured the mechanical quality factor of three fused silica samples with
coatings deposited on them. The loss angle of the coating material for strains
parallel to the coated surface was found to be (4.2 +- 0.3)*10^(-4) for
coatings deposited on commercially polished slides and (1.0 +- 0.3)*10^{-4} for
a coating deposited on a superpolished disk. Using these numbers, we estimate
the effect of coatings on thermal noise in the initial LIGO and advanced LIGO
interferometers. We also find that the corresponding prediction for thermal
noise in the 40 m LIGO prototype at Caltech is consistent with the noise data.
These results are complemented by results for a different type of coating,
presented in a companion paper.Comment: Submitted to LSC (internal) review Sept. 20, 2001. To be submitted to
Phys. Lett.
Misconceptions and generalizations of the Den Hartog galloping criterion
Classical quasi-steady galloping analysis deals exclusively with cases of across-wind vibrations, leaving aside the more general situation where the wind and motion may not be normal. This can arise in many circumstances, such as in the motion of a power transmission cable about its equilibrium configuration that is swayed from the vertical plane as a result of the mean wind or in a tall slender structure in a skewed wind. Furthermore, the generalization to such situations, when this had been made, has only considered special issues. In this paper, the correct equations for the quasi-steady aerodynamic damping coefficients for a rotated system or wind are derived, and the differences from other variants are highlighted. Motion in two orthogonal structural planes is considered, potentially giving coupled translational galloping, for which previous analysis has often been limited or has even arrived at erroneous conclusions. For the two-degree-of-freedom case, the behavior is dependent on the structural as well as the aerodynamic parameters, in particular the orientation of the principal structural axes and the relative natural frequencies in the two planes. For the first time, the differences in the aerodynamic damping and zones of galloping instability are quantified between solutions from the correct perfectly tuned, well detuned, and classical Den Hartog equations (and also an incorrect generalization of the latter) for a variety of typical cross-sectional shapes. It is found that although the Den Hartog summation often gives a reasonable estimate for the actual aerodynamic damping, even in the rotated situation, in some circumstances the differences can be quite large
Terror from the Sky: Unconventional Linguistic Clues to the Negrito Past
Within recorded history. most Southeast Asian peoples have been of southern Mongoloid physical type, whether they speak Austroasiatic, Tibeto-Burman, Austronesian, Tai-Kadai, or Hmong-Mien languages. However, population distributions suggest that this is a post-Pleistocene phenomenon and that for tens of millennia before the last glaciation ended Greater Mainland Southeast Asia, which included the currently insular world that rests on the Sunda Shelf, was peopled by short, dark-skinned, frizzy-haired foragers whose descendants in the Philippines came to be labeled by the sixteenth-century Spanish colonizers as negritos, a term that has since been extended to similar groups throughout the region. There are three areas in which these populations survived into the present so as to become part of written history: the Philippines, the Malay Peninsula, and the Andaman Islands. All Philippine negritos speak Austronesian languages, and all Malayan negritos speak languages in the nuclear Mon-Khmer branch of Austroasiatic, but the linguistic situation in the Andamans is a world apart. Given prehistoric language shifts among both Philippine and Malayan negritos, the prospects of determining whether disparate negrito populations were once a linguistically or culturally unified community would appear hopeless. Surprisingly, however, some clues to a common negrito past do survive in a most unexpected way
Tension pneumothorax in a newborn after Cesarean-section delivery -A case report-
Tension pneumothorax in newborns is a rare but life-threatening complication. We encountered a case of a full-term neonate with a breech presentation. An elective cesarean section was scheduled. Immediately after delivery, the newborn was found to be breathless with a heart rate <60/min. During intubation and cardiac massage, the patient's femoral artery and vein were accessed. The infantogram revealed a right side tension pneumothorax. A 22 gauge needle thoracentesis relieved the right side chest pressure and a closed thoracostomy was performed. The severe acidosis was corrected with sodium bicarbonate. The patient was managed in the neonatal intensive care unit, but died from uncorrectable acidosis. We report this case with a review of the relevant literature
Redesign of plates by large admissible perturbations
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76482/1/AIAA-12089-360.pd
Distribution Free Estimation of Spatial Autoregressive Binary Choice Panel Data Models
Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon
Identifying effective treatment combinations for MS patients failing standard therapy is an important goal. We report the results of a phase II open label baseline-to-treatment trial of a humanized monoclonal antibody against CD25 (daclizumab) in 10 multiple sclerosis patients with incomplete response to IFN-β therapy and high brain inflammatory and clinical disease activity. Daclizumab was very well tolerated and led to a 78% reduction in new contrast-enhancing lesions and to a significant improvement in several clinical outcome measures
Comparing phoneme frequency, age of acquisition, and loss in aphasia:Implications for phonological universals
Phonological complexity may be central to the nature of human language. It may shape the distribution of phonemes and phoneme sequences within languages, but also determine age of acquisition and susceptibility to loss in aphasia. We evaluated this claim using frequency statistics derived from a corpus of phonologically transcribed Italian words (phonitalia, available at phonitalia,org), rankings of phoneme age of acquisition (AoA) and rate of phoneme errors in patients with apraxia of speech (AoS) as an indication of articulatory complexity. These measures were related to cross-linguistically derived markedness rankings. We found strong correspondences. AoA, however, was predicted by both apraxic errors and frequency, suggesting independent contributions of these variables. Our results support the reality of universal principles of complexity. In addition they suggest that these complexity principles have articulatory underpinnings since they modulate the production of patients with AoS, but not the production of patients with more central phonological difficulties
A genome-wide association study for diabetic nephropathy genes in African Americans
A genome-wide association study was performed using the Affymetrix 6.0 chip to identify genes associated with diabetic nephropathy in African Americans. Association analysis was performed adjusting for admixture in 965 type 2 diabetic African American patients with end-stage renal disease (ESRD) and in 1029 African Americans without type 2 diabetes or kidney disease as controls. The top 724 single nucleotide polymorphisms (SNPs) with evidence of association to diabetic nephropathy were then genotyped in a replication sample of an additional 709 type 2 diabetes-ESRD patients and 690 controls. SNPs with evidence of association in both the original and replication studies were tested in additional African American cohorts consisting of 1246 patients with type 2 diabetes without kidney disease and 1216 with non-diabetic ESRD to differentiate candidate loci for type 2 diabetes-ESRD, type 2 diabetes, and/or all-cause ESRD. Twenty-five SNPs were significantly associated with type 2 diabetes-ESRD in the genome-wide association and initial replication. Although genome-wide significance with type 2 diabetes was not found for any of these 25 SNPs, several genes, including RPS12, LIMK2, and SFI1 are strong candidates for diabetic nephropathy. A combined analysis of all 2890 patients with ESRD showed significant association SNPs in LIMK2 and SFI1 suggesting that they also contribute to all-cause ESRD. Thus, our results suggest that multiple loci underlie susceptibility to kidney disease in African Americans with type 2 diabetes and some may also contribute to all-cause ESRD
- …