250 research outputs found

    ‘The play’s the thing’: A creative collaboration to investigate lived experiences in an urban community garden

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    Presenting the backstage story of a non-traditional qualitative research project, I illustrate how a creative approach can stimulate participant dialogue and encourage researcher reflexivity. Working with an award-winning playwright and the staff and volunteers at a community garden, I explored the meanings of connections between people and nature, and how these connections impact well-being, through a collaborative performance ethnography. The aim of the study is to stimulate discourse around the role of community gardens in enacting social and environmental change for well-being. This article is an exploration of how the creative approach we adopted, incorporating arts-based inquiry and performance as method, contributed to every aspect of the research process. First, it facilitated relaxed communications with the members of the community organisation who participated. Their interest was immediately piqued by the idea of being involved in the development of a play, which led to relaxed, playful discussion. Second, the creative approach provided new perspectives on the collection and analysis of data. It expanded my thinking, in developing my methodological approach to the research and in working towards a radical reflexivity. I suggest that creative approaches are applicable to many areas of organisational research

    The Disciplined Writer: Two Steps to Creating Academically Legitimate Integration Papers

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    The academic vocation has two parts: teaching and scholarship. As a matter of practical spirituality, there are increasing calls for Christian business professors to do research, particularly faith-integration research. This paper outlines the process by which faith-integration scholarship can be mapped on the academic writing process. Specifically, the key issues of legitimacy - quality and rigor - are discussed. Finally, we offer two practical principles for the writer of academically legitimate integration papers: The Rule of Three, and The Rule of Ten Thousand and give examples of how to apply each

    Detection and reporting of ranavirus in amphibians:Evaluation of the roles of the world organisation for animal health and the published literature

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    Pathogens of wildlife can have direct impacts on human and livestock health as well as on biodiversity, as causative factors in population declines and extinctions. The World Organization for Animal Health (OIE) seeks to facilitate rapid sharing of information about animal diseases to enable up-to-date risk assessments of translocations of animals and animal products. The OIE also produces manuals of recommended methods to standardize diagnostic testing. Ranaviruses are important amphibian pathogens that may have spread through international trade, and infections became notifiable to OIE in 2009. We surveyed and reviewed published literature for data on sampling, diagnostic testing, and reporting of ranavirus during 2009–2014. We also investigated attitudes and awareness of the OIE and its recommendations for best practice. We found that sampling effort is uneven and concentrated in the northern hemisphere. We also identified citizen science projects that have the potential to improve the quantity and quality of data on the incidence of ranavirus infection and the circumstances surrounding disease outbreaks. We found reporting of infection to be inconsistent: reporting was split between the published literature (where it was subject to a 2-yr lag) and the OIE with little overlap, results of negative diagnostic tests were underreported, and scientific researchers lacked awareness of the role of the OIE. Approaches to diagnostic screening were poorly harmonized and heavily reliant on molecular methods. These flaws in the mechanisms of ranavirus detection and reporting hamper the construction of a comprehensive disease information database

    The Millennial Generation and Personal Accountability: Spiritual and Classroom Implications

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    A majority of students who currently populate university classrooms represent an age group that has been labeled “The Millennial Generation,” a generation widely believed to lack personal accountability. This paper discusses accountability in relation to Scripture and proposes that it is a personal quality that is important to an individual and to God. We then apply these ideas to characteristics of the Millennial Generation. Throughout the paper, we also introduce classroom techniques that are intended to teach accountability and are designed to appeal to Millennials

    A dominant mutation within the DNA-binding domain of the bZIP transcription factor Maf causes murine cataract and results in selective alteration in DNA binding

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    The murine autosomal dominant cataract mutants created in mutagenesis experiments have proven to be a powerful resource for modelling the biological processes involved in cataractogenesis. We report a mutant which in the heterozygous state exhibits mild pulverulent cataract named ‘opaque flecks in lens', symbol Ofl. By molecular mapping, followed by a candidate gene approach, the mutant was shown to be allelic with a knockout of the bZIP transcription factor, Maf. Homozygotes for Ofl and for Maf null mutations are similar but a new effect, renal tubular nephritis, was found in Ofl homozygotes surviving beyond 4 weeks, which may contribute to early lethality. Sequencing identified the mutation as a G→A change, leading to the amino-acid substitution mutation R291Q in the basic region of the DNA-binding domain. Since mice heterozygous for knockouts of Maf show no cataracts, this suggests that the Ofl R291Q mutant protein has a dominant effect. We have demonstrated that this mutation results in a selective alteration in DNA binding affinities to target oligonucleotides containing variations in the core CRE and TRE elements. This implies that arginine 291 is important for core element binding and suggests that the mutant protein may exert a differential downstream effect amongst its binding targets. The cataracts seen in Ofl heterozygotes and human MAF mutations are similar to one another, implying that Ofl may be a model of human pulverulent cortical cataract. Furthermore, when bred onto a different genetic background Ofl heterozygotes also show anterior segment abnormalities. The Ofl mutant therefore provides a valuable model system for the study of Maf, and its interacting factors, in normal and abnormal lens and anterior segment developmen

    Coping with methodological dilemmas; about establishing the effectiveness of interventions in routine medical practice

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    BACKGROUND: The aim of this paper is to show how researchers balance between scientific rigour and localisation in conducting pragmatic trial research. Our case is the Quattro Study, a pragmatic trial on the effectiveness of multidisciplinary patient care teams used in primary health care centres in deprived neighbourhoods of two major cities in the Netherlands for intensified secondary prevention of cardiovascular diseases. METHODS: For this study an ethnographic design was used. We observed and interviewed the researchers and the practice nurses. All gathered research documents, transcribed observations and interviews were analysed thematically. RESULTS: Conducting a pragmatic trial is a continuous balancing act between meeting methodological demands and implementing a complex intervention in routine primary health care. As an effect, the research design had to be adjusted pragmatically several times and the intervention that was meant to be tailor-made became a rather stringent procedure. CONCLUSION: A pragmatic trial research is a dynamic process that, in order to be able to assess the validity and reliability of any effects of interventions must also have a continuous process of methodological and practical reflection. Ethnographic analysis, as we show, is therefore of complementary value

    Early Maternal Time Investment and Early Child Outcomes

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    Using large longitudinal survey data from the UK Millennium Cohort Study, this article estimates the relationship between maternal time inputs and early child development. We find that maternal time is a quantitatively important determinant of skill formation and that its effect declines with child age. There is evidence of long‐term effects of early maternal time inputs on later outcomes, especially in the case of cognitive skill development. In the case of non‐cognitive development, the evidence of this long‐term impact disappears when we account for skill persistence

    Tailoring intervention procedures to routine primary health care practice; an ethnographic process evaluation

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    Background. Tailor-made approaches enable the uptake of interventions as they are seen as a way to overcome the incompatibility of general interventions with local knowledge about the organisation of routine medical practice and the relationship between the patients and the professionals in practice. Our case is the Quattro project which is a prevention programme for cardiovascular diseases in high-risk patients in primary health care centres in deprived neighbourhoods. This programme was implemented as a pragmatic trial and foresaw the importance of local knowledge in primary health care and internal, or locally made, guidelines. The aim of this paper is to show how this prevention programme, which could be tailored to routine care, was implemented in primary care. Methods. An ethnographic design was used for this study. We observed and interviewed the researchers and the practice nurses. All the research documents, observations and transcribed interviews were analysed thematically. Results. Our ethnographic process evaluation showed that the opportunity of tailoring intervention procedures to routine care in a pragmatic trial setting did not result in a well-organised and well-implemented prevention programme. In fact, the lack of standard protocols hindered the implementation of the intervention. Although it was not the purpose of this trial, a guideline was developed. Despite the fact that the developed guideline functioned as a tool, it did not result in the intervention being organised accordingly. However, the guideline did make tailoring the intervention possible. It provided the professionals with the key or the instructions needed to achieve organisational change and transform the existing interprofessional relations. Conclusion. As tailor-made approaches are developed to enable the uptake of interventions in routine practice, they are facilitated by the brokering of tools such as guidelines. In our study, guidelines facilitated organisational change and enabled the transformation of existing interprofessional relations, and thus made tailoring possible. The attractive flexibility of pragmatic trial design in taking account of local practice variations may often be overestimated
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