740 research outputs found
Liquid laser cavities
Liquid laser cavities have plenum chambers at the ends of the capillary cell which are terminated in transparent optical flats. By use of these cavities, several new europium chelates and a terbium chelate can provide laser action in solution at room temperature
Analyzing false memories in children with associative lists specific for their age
Two experiments attempted to resolve previous contradictory findings concerning developmental trends in false memories within the Deese-Roediger-McDermott (DRM) paradigm by using an improved methodology-constructing age-appropriate associative lists. The research also extended the DRM paradigm to preschoolers. Experiment 1 (N = 320) included children in three age groups (preschoolers of 3-4 years, second-graders of 7-8 years, and preadolescents of 11-12 years) and adults, and Experiment 2 (N = 64) examined preschoolers and preadolescents. Age-appropriate lists increased false recall. Although preschoolers had fewer false memories than the other age groups, they showed considerable levels of false recall when tested with age-appropriate materials. Results were discussed in terms of fuzzy-trace, source-monitoring, and activation frameworks
Gain without population inversion in V-type systems driven by a frequency-modulated field
We obtain gain of the probe field at multiple frequencies in a closed
three-level V-type system using frequency modulated pump field. There is no
associated population inversion among the atomic states of the probe
transition. We describe both the steady-state and transient dynamics of this
system. Under suitable conditions, the system exhibits large gain
simultaneously at series of frequencies far removed from resonance. Moreover,
the system can be tailored to exhibit multiple frequency regimes where the
probe experiences anomalous dispersion accompanied by negligible
gain-absorption over a large bandwidth, a desirable feature for obtaining
superluminal propagation of pulses with negligible distortion.Comment: 10 pages + 8 figures; To appear in Physical Review
Narrowband frequency tunable light source of continuous quadrature entanglement
We report the observation of non-classical quantum correlations of continuous
light variables from a novel type of source. It is a frequency non-degenerate
optical parametric oscillator below threshold, where signal and idler fields
are separated by 740MHz corresponding to two free spectrum ranges of the
parametric oscillator cavity. The degree of entanglement observed, - 3.8 dB, is
the highest to-date for a narrowband tunable source suitable for atomic quantum
memory and other applications in atomic physics. Finally we use the latter to
visualize the Einstein-Podolsky-Rosen paradox.Comment: 11 pages, 9 figures, LaTe
Improving Strategies via SMT Solving
We consider the problem of computing numerical invariants of programs by
abstract interpretation. Our method eschews two traditional sources of
imprecision: (i) the use of widening operators for enforcing convergence within
a finite number of iterations (ii) the use of merge operations (often, convex
hulls) at the merge points of the control flow graph. It instead computes the
least inductive invariant expressible in the domain at a restricted set of
program points, and analyzes the rest of the code en bloc. We emphasize that we
compute this inductive invariant precisely. For that we extend the strategy
improvement algorithm of [Gawlitza and Seidl, 2007]. If we applied their method
directly, we would have to solve an exponentially sized system of abstract
semantic equations, resulting in memory exhaustion. Instead, we keep the system
implicit and discover strategy improvements using SAT modulo real linear
arithmetic (SMT). For evaluating strategies we use linear programming. Our
algorithm has low polynomial space complexity and performs for contrived
examples in the worst case exponentially many strategy improvement steps; this
is unsurprising, since we show that the associated abstract reachability
problem is Pi-p-2-complete
Predicting sexual problems in women: The relevance of sexual excitation and sexual inhibition
This is the post-print version of the article. The official published version can be obtained from the link below.Data from a non-clinical sample of 540 heterosexual women were used to examine the relationships between scores on the Sexual Excitation/Sexual Inhibition Inventory for Women (SESII-W) and ratings of current sexual problems, lifetime arousal difficulty, lifetime orgasm difficulty, and lifetime problems with low sexual interest. Multiple regression analyses also included several demographic/background variables as predictors: age, full-time employment, completed college, children in household, married, health ratings, importance of sex, and whether the woman was in a sexual relationship. The strongest statistical predictors of both current and lifetime sexual problems were the SESII-W inhibition factors Arousal Contingency and Concerns about Sexual Function. Demographic factors did not feature largely in any of the models predicting sexual problems even when statistically significant relationships were found. If future research supports the predictive utility of the SESII-W in identifying women who are more likely to experience sexual difficulties, these scales may be used as prognostic factors in treatment studies.This study was funded, in part, by a grant from the Lilly Centre for Women's Health
Challenges and support needs of parents and children when a parent is at end of life: A systematic review
Background: Preparing children for the death of a parent is challenging. Parents are often uncertain if and how to communicate and support their children. Many parents feel it is protecting their children by not telling them about the prognosis. Children less prepared for parental death from a terminal illness are more susceptive to later adversities. To facilitate coping and moderate for such adversities, there is a need to gain insight and understand the experience and challenges confronted by families.
Aim: This review synthesised evidence on the experiences of parents and children when a parent is at end of life to discern their challenges, support needs and factors that facilitated good practice.
Design: Mixed-methods systematic review.
Data sources: Four electronic databases (CINAHL, PubMed, PsycINFO and Ovid MEDLINE) using MeSH terms and word searches in October 2018. Studies were not limited by year of publication, language or country. Grey literature searches were also completed on Google Scholar and OpenGrey.
Results: In all, 7829 records were identified; 27 qualitative and 0 quantitative studies met the inclusion criteria. Eight descriptive themes were identified, further categorised into two broad themes: (1) barriers and facilitators in sharing the news that a parent is dying and (2) strategies to manage the changing situation.
Conclusion: Lack of understanding in relation to the parent’s prognosis, denial and feeling ill-equipped were suggested as barriers for parents to share the news with their children. Engagement with social networks, including extended family relatives and peers, and maintaining routines such as attending school were suggested supportive by parents and children. Findings are limited primarily to White, middle-class two-parent families. A number of areas for future research are identified.</p
Quantum noise in the position measurement of a cavity mirror undergoing Brownian motion
We perform a quantum theoretical calculation of the noise power spectrum for
a phase measurement of the light output from a coherently driven optical cavity
with a freely moving rear mirror. We examine how the noise resulting from the
quantum back action appears among the various contributions from other noise
sources. We do not assume an ideal (homodyne) phase measurement, but rather
consider phase modulation detection, which we show has a different shot noise
level. We also take into account the effects of thermal damping of the mirror,
losses within the cavity, and classical laser noise. We relate our theoretical
results to experimental parameters, so as to make direct comparisons with
current experiments simple. We also show that in this situation, the standard
Brownian motion master equation is inadequate for describing the thermal
damping of the mirror, as it produces a spurious term in the steady-state phase
fluctuation spectrum. The corrected Brownian motion master equation [L. Diosi,
Europhys. Lett. {\bf 22}, 1 (1993)] rectifies this inadequacy.Comment: 12 pages revtex, 2 figure
SPATIOTEMPORAL REORGANIZATION OF GROWTH RATES IN THE EVOLUTION OF ONTOGENY
Heterochrony, evolutionary changes in rate or timing of development producing parallelism between ontogeny and phylogeny, is viewed as the most common type of evolutionary change in development. Alternative hypotheses such as heterotopy, evolutionary change in the spatial patterning of development, are rarely entertained. We examine the evidence for heterochrony and heterotopy in the evolution of body shape in two clades of piranhas. One of these is the sole case of heterochrony previously reported in the group; the others were previously interpreted as cases of heterotopy. To compare ontogenies of shape, we computed ontogenetic trajectories of shape by multivariate regression of geometric shape variables (i.e., partial warp scores and shape coordinates) on centroid size. Rates of development relative to developmental age and angles between the trajectories were compared statistically. We found a significant difference in developmental rate between species of Serrasalmus , suggesting that heterochrony is a partial explanation for the evolution of body shape, but we also found a significant difference between their ontogenetic transformations; the direction of the difference between them suggests that heterotopy also plays a role in this group. In Pygocentrus we found no difference in developmental rate among species, but we did find a difference in the ontogenies, suggesting that heterotopy, but not heterochrony, is the developmental basis for shape diversification in this group. The prevalence of heterotopy as a source of evolutionary novelty remains largely unexplored and will not become clear until the search for developmental explanations looks beyond heterochrony.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72102/1/j.0014-3820.2000.tb00568.x.pd
Upregulation of the Wnt Co-Receptor LRP6 Promotes Hepatocarcinogenesis and Enhances Cell Invasion
Background: Activation of the Wnt/b-catenin signaling pathway plays a crucial role in hepatocellular carcinoma (HCC). Lowdensity lipoprotein (LDL) receptor-related protein-6 (LRP6) is one of the co-receptors of the Wnt/b-catenin pathway and forms a signaling complex with Wnt ligand and Frizzled receptor to activate downstream signaling. However, the role of LRP6 in hepatocarcinogenesis is unclear. In this study, we examined its expression and roles in human HCC. Methodology/Principal Findings: Using real-time quantitative RT-PCR, we found that LRP6 was frequently (45%) overexpressed in human HCCs (P = 0.003). In vitro studies showed that ectopic expression of LRP6 increased the protein level of b-catenin. Moreover, overexpression of the full-length and constitutively active LRP6, respectively, activated the WNT/b-catenin signaling pathway, as shown by the TCF/b-catenin reporter assay. With regard to the effects of LRP6 overexpression in HCC cells, stable overexpression of the constitutively active LRP6 in BEL-7402 HCC cells enhanced cell proliferation, cell migration, and invasion in vitro as well as tumorigenicity in nude mice. Conclusions/Significance: Our findings indicate that overexpression of LRP6 contributes to the hyperactivation of the Wnt
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