Spurious hypertriglyceridaemia in unconscious patient

Background: Routine biochemical investigation of one patient admitted with a diagnosis of CVA as mentioned in the requisition revealed high hypertriglyceridaemia in a non-lipemic serum for the first time. Later, after scrutiny of the case sheet in the ward, it was found that apart from other management, blood was drawn about 90 minutes after administration of 4th dose of oral glycerol through nasogastric tube and sent to the laboratory. This was suspected to be the probable cause. In order to find out the degree of interference in blood sample, a small amount of glycerol was brought from the ward to experiment.Methods: Glycerol was initially diluted to 1 in 100 in distilled water and then artificially mixed in various dilutions with pooled serum from indoor patients and pooled heparinized plasma from outdoor patients. These samples were subjected to triglycerides estimation while routine analyses were going on.Results: A concentration of about 13,50,500 mg/dl falsely measured triglycerides was found in glycerol solution. This needed a dilution of 1 in 1500 for distilled water, serum and plasma which had 0, 190 and 113 mg/dl triglycerides respectively to bring the level to near the highest range of linearity. The recovery of added glycerol in distilled water was almost 100% but there was some positive bias more with plasma than serum.Conclusions: The spurious hypertriglyceridaemia in serum resulted from positive interference due to temporary high glycerolaemia by the commonly employed GPO-PAP method for its measurement and would cause the same depending on glycerol level.

Intriguing haemorrhages: a review of last seven decades (1951-2021)

Bleeding as a cause of underlying psychological or psychiatric disorder is hardly ever thought of mainly due to unawareness and rarity. An overview will help to understand the real problem. A detailed literature survey of different types of bleeding from various parts of the body for which the reasons could not be diagnosed easily was made over last seven decades (1951-2021). These have been presented mainly in tabular form and also, in the text as briefly as possible to have a comprehensive overview only. The contents portray the nature, triggers and spectrum of settings in which haemorrhages occurred including the explanations which were available from the articles. In addition, some of my personal conjectures as possible causes have also been included. Unexplained bleeding might be psychological or psychiatric in origin. Awareness about this will enable to diagnose the case at the earliest and accordingly, the management can be started. Different types of such haemorrhage including particularly those due to idiopathic causes are potential areas of research.

Imidazolium Ionic Liquid-Supported Schiff Base and Its Transition Metal Complexes: Synthesis, Physicochemical Characterization and Exploration of Antimicrobial Activities

New Co(II), Ni(II) and Cu(II) metal complexes from an imidazolium ionic liquid supported Schiff base, 1-{2-(2-hydroxy-5-nitrobenzylideneamino)ethyl}-3-ethylimidazolium tetrafluoroborate were synthesized and characterized by different analytical and spectroscopic techniques such as elemental analysis (CHN analysis), UV-Visible, 1H NMR, 13C NMR, FT-IR, powder X-ray diffraction, mass-spectra, magnetic susceptibility measurements and molar conductance data. From these spectroscopic and analytical data, tetra coordinated 1:2 metal-ligand stoichiometry was suggested for the metal complexes. The molar conductance data of the complexes revealed their electrolytic nature (1:2). The synthesized complexes along with the ligand were screened for in vitro antibacterial applications against Gram-negative and Gram-positive bacteria to assess their inhibition potentials. The complexes were proved very effective against the tested organisms

Seiberg-Witten map and Galilean symmetry violation in a non-commutative planar system

An effective U(1) gauge invariant theory is constructed for a non-commutative Schrodinger field coupled to a background U(1)_{\star} gauge field in 2+1-dimensions using first order Seiberg-Witten map. We show that this effective theory can be cast in the form of usual Schrodinger action with interaction terms of noncommutative origin provided the gauge field is of ``background'' type with constant magnetic field. The Galilean symmetry is investigated and a violation is found in the boost sector. We also consider the problem of Hall conductivity in this framework.Comment: REVTeX, 4 pages, Title changed, Paper shortened, Appendix removed, A new section on Galilean symmetry adde

Producing Linked Open Dataset from Bibliographic Data with Integration of External Data Sources for Academic Libraries

This paper has focused on transformation of bibliographic data to linked open data (LOD) as RDF(Resource Description Framework) triple model with integration of external resources. Library & Information centres and knowledge centres deal with various types of databases like bibliographic databases, full text databases, archival databases, statistical databases, CD/DVD ROM databases and more. Presently, web technology changes storing, processing, and disseminating services rapidly. The semantic web technology is an advance technology of web platform which provides structured data on web for describing and retrieving by the organization or institutions. It may provide more information from other external resources to the users. The main objective of this paper is transformation of library bibliographic data, based on MARC21, to RDF triple format as LOD with enrichment of external LOD dataset. External resources like OpenLibrary, VIAF, Wikidata, DBpedia, GeoNames etc. We have proposed a Workflow model (Figure-1) to visualize details steps, activities, components for transforming bibliographic data to LOD dataset. The methodology of this work includes the various methods and steps for conducting such research work. Here we have used an open source tool OpenRefine (version 3.2), formally it is known as GoogleRefine. The OpenRefine tool is used for managing and organizing the messy data with different attribute like row-column manipulation, reconciliation manipulation, different format manipulation like XML, JSON, N-Triple, RDF etc. The OpenRefine tool has played the various roles for the research work such as insertion of URI column, link generation, reconciliation data for external sources, conversion of source format to RDF format etc. After conversion of whole bibliographic data into RDF triple format as considerable LOD dataset. At the production page we may find a RDF file of bibliographic data. This LOD dataset may further be used by the organizations or institutions for their advanced bibliographic service

Synthesis, physico-chemical characterization and antibacterial studies of new Fe(III) and Cr(III) complexes with an ionic liquid-supported Schiff base ligand

155-161An ionic liquid-supported Schiff base 1-{2-(2-hydroxy-5-bromobenzylamine)ethyl}-3-ethylimidazolium tetrafluoroborate and its Fe(III) and Cr(III) complexes has been prepared and characterized by various analytical and spectroscopic methods such as elemental analysis, UV-visible, FTIR, 1H NMR, mass spectra, TGA/DTG, molar conductance and magnetic susceptibility measurements. Based on these spectral studies octahedral geometry has been proposed for both complexes. Molar conductance of the complexes is showing their electrolytic nature. The Schiff base ligand and its complexes have tested for in vitro antibacterial activities against gram positive and gram negative bacteria to assess their inhibition potentials. Cr(III) complex has shown higher activity than the Fe(III) complex against the tested bacteria S. aureus and E. coli.</em

A comparative study between large deformation finite element and limit equilibrium methods of slope stability analysis

Limit equilibrium (LE) methods are widely used to analyze the stability of earthen slopes. In the LE methods, resistance along the critical failure plane is compared against the sum of the driving forces resulted from different sources such as gravity and earthquake. The ratio between the resistance and driving force is expressed as factor of safety (Fs). The Fs does not provide any information about deformation behaviour although it could be a design criteria. The mechanism of failure and deformation behaviour can be better modeled using recently advanced numerical techniques such as finite element (FE) methods. Although FE modeling techniques have been improved significantly over the last few decades, most of the current FE methods have been developed for small strain analysis in Lagrangian framework. However, in large-scale landslides, significant shear displacement occurs along the failure plane that cannot be modeled using the conventional Lagrangian-based FE techniques because of numerical issues resulting from significant mesh distortion. In the present study, the Coupled Eulerian-Lagrangian (CEL) approach in Abaqus is used to simulate large deformation behaviour of slope failure. Analyses are also performed using the limit equilibrium methods in SLOPE/W software. The present study focuses on two critical factors: earthquake loading and retrogression in sensitive clay slopes. Comparison of different methods of analysis shows that Abaqus CEL can successfully simulate the failure process from small- to large-deformation levels. Based on a comprehensive parametric study, different types of failure as reported in the literature from post-failure investigations could be simulated, which cannot be done using the LE method or Lagrangian-based FE technique