Conformal Antenna Array for Millimeter-Wave Communications: Performance Evaluation

In this paper, we study the influence of the radius of a cylindrical supporting structure on radiation properties of a conformal millimeter-wave antenna array. Bent antenna array structures on cylindrical surfaces may have important applications in future mobile devices. Small radii may be needed if the antenna is printed on the edges of mobile devices and in items which human beings are wearing, such as wrist watches, bracelets and rings. The antenna under study consists of four linear series-fed arrays of four patch elements and is operating at 58.8 GHz with linear polarization. The antenna array is fabricated on polytetrafluoroethylene substrate with thickness of 0.127 mm due to its good plasticity properties and low losses. Results for both planar and conformal antenna arrays show rather good agreement between simulation and measurements. The results show that conformal antenna structures allow achieving large angular coverage and may allow beam-steering implementations if switches are used to select between different arrays around a cylindrical supporting structure.Comment: Keywords: conformal antenna, millimeter-wave communications, patch antenna array. 11 pages, 10 figures, 1 tabl

Analycity and smoothing effect for the coupled system of equations of Korteweg - de Vries type with a single point singularity

We study that a solution of the initial value problem associated for the coupled system of equations of Korteweg - de Vries type which appears as a model to describe the strong interaction of weakly nonlinear long waves, has analyticity in time and smoothing effect up to real analyticity if the initial data only has a single point singularity at $x=0.

Holographic quark matter with colour superconductivity and a stiff equation of state for compact stars

We present a holographic model of QCD with a first order chiral restoration phase transition with chemical potential, mu. The first order behaviour follows from allowing a discontinuity in the dual description as the quarks are integrated out below their constituent mass. The model predicts a deconfined yet massive quark phase at intermediate densities (350 MeV< mu <500 MeV), above the nuclear density phase, which has a very stiff equation of state and a speed of sound close to one. We also include a holographic description of a colour superconducting condensate in the chirally restored vacuum and study the resulting equation of state. They provides a well behaved first order transition from the deconfined massive quark phase at very high density (mu>500 MeV). We solve the Tolman-Oppenheimer-Volkoff equations with the resulting equations of state and find stable hybrid stars with quark cores. We compute the tidal deformability for these hybrid stars and show they are consistent with LIGO/Virgo data on a neutron star collision. Our holographic model shows that quark matter could be present at the core of such compact stars.Comment: 17 pages, 14 figure

Evaluation of trace calls by Xpert MTB/RIF ultra for clinical management in low TB burden settings

Background Clinical interpretation of trace results by Xpert MTB/RIF Ultra assay (Ultra) used as an initial diagnostic test for tuberculosis (TB) may be challenging. The aim of the study was to evaluate the frequency and epidemiology of trace readouts in routine clinical practice in a low TB prevalence setting and to propose guidance on how to manage patients with trace calls considering the data available (clinical, radiological, bacteriological etc.). Materials and methods A retrospective, observational, monocentric study was conducted at IRCCS Azienda Ospedaliero-Universitaria of Bologna, Italy between November 2017—December 2020. Presumptive TB patients with at least one Ultra trace result during diagnostic workup before treatment were included in the study. Patients with ongoing anti-TB treatment at the time of the trace call result or with no clinical data available were excluded from the study. Results Fifty-nine presumptive TB patients with Ultra trace readouts were included in the study (mean age 37.0 years, 61% males). Four patients had a history of TB in the last 2 years. Twenty-five (42.4%) of the 59 samples with trace results were respiratory material. 57/59 (96.6%) patients started anti-TB treatment soon after obtaining trace results, based on clinical, radiological or other information available, while for two patients with a recent history of TB the trace result did not lead to anti-TB treatment. Culture was positive for M. tuberculosis for 31/59 (52.5%) samples with trace calls: 13/25 (52.0%) were respiratory samples and 18/33 (54.5%) non-respiratory samples. The clinical and/or radiological findings of 47/57 (82.4%) patients given anti-TB therapy improved during treatment. Conclusion In low TB incidence settings, Ultra trace calls in presumptive TB patients should be considered as true-positive and treatment should be started promptly, except in cases of recent history of TB, where careful evaluation of other diagnostic criteria is necessary before starting anti-TB treatment. A decisional algorithm for clinical management is proposed

IGRA test for TB in COVID-19: role of corticosteroids

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Burrknots as food source for larval development of Grapholita molesta (Lepidoptera: Tortricidae) on apple trees.

Grapholita molesta (Busck) is one of the main pests of apple trees, and lives on their shoots and fruits. In southern Brazil, the insect is also found on old branches and structures similar to aerial roots, so-called burrknots. This study evaluated the development and population growth potential of G. molesta fed on burrknots, compared with apple fruit cultivar. Fuji and a corn-based artiÞcial diet. The study was carried out in the laboratory under controlled temperature (25 1C), relative humidity (7010%), and photophase (16 h). The biological parameters of the immature and adult stages were determined, and a fertility life table was constructed. Insects fed on burrknots showed a longer duration and a lower survival for the egg-to-adult period (29.3 d and 22.5%) compared with those that fed on apples (25.1 d and 30.0%) and artiÞcial diet (23.9 d and 54.8%). Insects reared on aerial roots had a lower pupal weight (10.0 mg) compared with those reared on either artiÞcial diet (13.7 mg) or apple cultivar. Fuji (12.4 mg). The fecundity and longevity of males and females did not signiÞcantly differ for the three foods. Based on the fertility life table, insects reared on burrknots had the lowest net reproductive rate (Ro), intrinsic rate of population growth (rm) and finite rate of increase, compared with insects reared on artiÞcial diet and apple fruit. Burrknots support the development of the complete cycle of G. molesta, which allows populations of this pest to increase in orchards

Investigating the Origin of Mycobacterium chimaera Contamination in Heater-Cooler Units: Integrated Analysis with Fourier Transform Infrared Spectroscopy and Whole-Genome Sequencing

Mycobacterium chimaera is ubiquitously spread in the environment, including factory and hospital water systems. Invasive cases of M. chimaera infection have been associated with aerosols produced by the use of heater-cooler units (HCU) during cardiac surgery. The aim of this study was to evaluate for the first time the performance of IR-Biotyper system on a large number of M. chimaera isolates collected from longitudinal environmental HCUs samples and water sources from hospitals located in three Italian provinces. In addition, IR-Biotyper results were compared with whole-genome sequencing (WGS) analysis, the reference method for molecular epidemiology, to investigate the origin of M. chimaera contamination of HCUs. From November 2018 to May 2021, 417 water samples from 52 HCUs (Stockert 3T, n = 41 and HCU40, n = 11) and 23 hospital taps (used to fill the HCU tanks) were concentrated, decontaminated, and cultured for M. chimaera. Positive cultures (n = 53) were purified by agar plate subcultures and analyzed by IR-Biotyper platform and Ion Torrent sequencing system. IR-Biotyper spectra results were analyzed using a statistical approach of dimensionality reduction by linear discriminant analysis (LDA), generating three separate clusters of M. chimaera, ascribable to each hospital. Furthermore, the only M. chimaera-positive sample from tap water clustered with the isolates from the HCUs of the same hospital, confirming that the plumbing system could represent the source of HCU contamination and, potentially, of patient infection. According to the genome-based phylogenies and following the classification proposed by van Ingen and collaborators in 2017, three distinct M. chimaera groups appear to have contaminated the HCU water systems: subgroups 1.1, 2.1, and branch 2. Most of the strains isolated from HCUs at the same hospital share a highly similar genetic profile. The nonrandom distribution obtained with WGS and IR-Biotyper leads to the hypothesis that M. chimaera subtypes circulating in the local plumbing colonize HCUs through the absolute filter, in addition with the current hypothesis that contamination occurs at the HCU production site. This opens the possibility that other medical equipment, such as endoscope reprocessing device or hemodialysis systems, could be contaminated by M. chimaera. IMPORTANCE Our manuscript focuses on interventions to reduce waterborne disease transmission, improve sanitation, and control infection. Sanitary water can be contaminated by nontuberculous Mycobacteria, including M. chimaera, a causative agent of invasive infections in immunocompromised patients. We found highly similar genetic and phenotypic profiles of M. chimaera isolated from heater-cooler units (HCU) used during surgery to thermo-regulate patients' body temperature, and from the same hospital tap water. These results lead to the hypothesis that M. chimaera subtypes circulating in the local plumbing colonize HCUs through the absolute filter, adding to the current hypothesis that contamination occurs at the HCU production site. In addition, this opens the possibility that other medical equipment using sanitized water, such as endoscope reprocessing devices or hemodialysis systems, could be contaminated by nontuberculous Mycobacteria, suggesting the need for environmental surveillance and associated control measures