Adaptive management in the context of barriers in European freshwater ecosystems

Many natural habitats have been modified to accommodate for the presence of humans and their needs. Infrastructures – such as hydroelectric dams, weirs, culverts and bridges – are now a common occurrence in streams and rivers across the world. As a result, freshwater ecosystems have been altered extensively, affecting both biological and geomorphological components of the habitats. Many fish species rely on these freshwater ecosystems to complete their lifecycles, and the presence of barriers has been shown to reduce their ability to migrate and sustain healthy populations. In the long run, barriers may have severe repercussions on population densities and dynamics of aquatic animal species. There is currently an urgent need to address these issues with adequate conservation approaches. Adaptive management provides a relevant approach to managing barriers in freshwater ecosystems as it addresses the uncertainties of dealing with natural systems, and accommodates for future unexpected events, though this approach may not be suitable in all instances. A literature search on this subject yielded virtually no output. Hence, we propose a step-by-step guide for implementing adaptive management, which could be used to manage freshwater barriers

Living with multiple sclerosis : women's experiences of sexuality and intimate relationships.

A literature review on the influences upon sexual adjustment following a chronic physical illness is reviewed. Results found that a variety of psychological, physical and social factors influence sexual adjustment. Research has explored the multiple factors, for example coping strategies and emotional adjustment. It was concluded that sexual adjustment is a complex process, which must be understood within a systemic context. The current study examined the impact of multiple sclerosis (MS) upon women’s sexuality and intimate relationships. Eleven women with MS were interviewed. Many factors affected sexuality and whether or not the women had positive intimate relationships. Among women with MS, sexual relationships needed to be understood within the wider context of their lives. Positive relationships with significant other people, such as their partners and wider society, were important to their sense of sexuality

An investigation of vegetation and other earth resource/feature parameters using LANDSAT and other remote sensing data. A: LANDSAT. B: Remote sensing of volcanic emissions

There are no author-identified significant results in this report

Mesothelial cells in tissue repair and fibrosis

Mesothelial cells are fundamental to the maintenance of serosal integrity and homeostasis and play a critical role in normal serosal repair following injury. However, when normal repair mechanisms breakdown, mesothelial cells take on a profibrotic role, secreting inflammatory, and profibrotic mediators, differentiating and migrating into the injured tissues where they contribute to fibrogenesis. The development of new molecular and cell tracking techniques has made it possible to examine the origin of fibrotic cells within damaged tissues and to elucidate the roles they play in inflammation and fibrosis. In addition to secreting proinflammatory mediators and contributing to both coagulation and fibrinolysis, mesothelial cells undergo mesothelial-to-mesenchymal transition, a process analogous to epithelial-to-mesenchymal transition, and become fibrogenic cells. Fibrogenic mesothelial cells have now been identified in tissues where they have not previously been thought to occur, such as within the parenchyma of the fibrotic lung. These findings show a direct role for mesothelial cells in fibrogenesis and open therapeutic strategies to prevent or reverse the fibrotic process

Natural variation in gestational cortisol is associated with patterns of growth in marmoset monkeys (Callithrix geoffroyi)

High levels of prenatal cortisol have been previously reported to retard fetal growth. Although cortisol plays a pivotal role in prenatal maturation, heightened exposure to cortisol can result in lower body weights at birth, which have been shown to be associated with adult diseases like hypertension and cardiovascular disease. This study examines the relationship between natural variation in gestational cortisol and fetal and postnatal growth in marmoset monkeys. Urinary samples obtained during the mother’s gestation were analyzed for cortisol. Marmoset body mass index (BMI) was measured from birth through 540 days in 30- or 60-day intervals. Multi-level modeling was used to test if marmoset growth over time was predicted by changes in gestational cortisol controlling for time, sex, litter, and litter size. The results show that offspring exposed to intra-uterine environments with elevated levels of cortisol had lower linear BMI rates of change shortly after birth than did offspring exposed to lower levels of cortisol, but exhibited a higher curvilinear growth rate during adolescence. Average daily change in gestational cortisol during the first trimester had a stronger relationship with postnatal growth than change during the third trimester. Higher exposure to cortisol during gestation does alter developmental trajectories, however there appears to be a catch-up period during later post-natal growth. These observations contribute to a larger discussion about the relationship of maternal glucocorticoids on offspring development and the possibility of an earlier vulnerable developmental window

The impact of national prenatal screening on the time of diagnosis and outcome of pregnancies affected with common trisomies, a cohort study in the Northern Netherlands

Background: To evaluate the impact of the introduction of prenatal screening on time of detection and pregnancy outcome for trisomy 21 (T21), trisomy 18 (T18) and trisomy 13 (T13). Methods: We performed a retrospective, population-based cohort study in the Northern Netherlands including 503 trisomy cases born between 2005 and 2012. Screening tests and invasive procedures, timing of diagnosis and pregnancy outcome were compared between the period before (2005-2006) and after introduction (2007-2012) using chi(2) tests. Results: There was an increase in proportion of women who had a prenatal screening and/or invasive test, from 62% in 2005-2006 to 84% in 2010-2012 (p 35 years (p <0.01). More T13/T18 cases were diagnosed <24 weeks after introduction (62% vs 84%; p <0.01). In T13/T18 intra-uterine death decreased (26% vs 15%), while terminations increased: 55% vs 72%. Conclusion: The introduction of prenatal screening had limited impact on the time of detection and outcome of the most common trisomies. The introduction of the 20-week anomaly scan has resulted in more trisomy cases diagnosed <24 weeks and a shift from fetal death to terminations

Oxidative stress and partial migration in brown trout (Salmo trutta)

During migration, animals are typically limited by their endogenous energetic resources that must be allocated to the physiological costs associated with locomotion, as well as avoiding and (or) compensating for oxidative stress. To date, there have been few attempts to understand the role of oxidative status in migration biology, particularly in fish. Semi-anadromous brown trout (Salmo trutta L., 1758) exhibit partial migration, where some individuals smoltify and migrate to sea, and others become stream residents, providing us with an excellent model to investigate the link between oxidative stress and migration. Using the brown trout, we obtained blood samples from juveniles from a coastal stream in Denmark in the fall prior to peak seaward migration that occurs in the spring, and assayed for antioxidant capacity (oxygen radical absorbance capacity) and oxidative stress levels (ratio of oxidized to reduced glutathione). We found that individuals that migrated had higher antioxidant capacity than residents and that future migration date was negatively correlated with both antioxidant capacity and body length in the fall. This study provides the first evidence that oxidative status is associated with migration strategy and timing, months in advance of the actual migration, and provides insight into the role of oxidative status in animal migration. </jats:p